PSPN (persephin) - Rat Genome Database

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Keyword

Gene: PSPN (persephin) Homo sapiens

Symbol:

PSPN

Name:

persephin

Description:

The protein encoded by this gene is a neurotrophic factor, belonging to the GDNF family. Neurotrophic factors are important for the proper development and maintenance of the nervous system. These factors promote neuronal survival and can prevent the neuronal degeneration associated with injury, toxin exposure, or neurodegenerative disease. The encoded protein has amino acid similarity to its other family members, glial cell line-derived neurotrophic factor and neurturin. This gene product promotes the survival of ventral midbrain dopaminergic neurons in culture and prevents their degeneration after 6-hydroxydopamine treatment in vivo. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

OTTHUMP00000237858; persephin; PSP

Orthologs:

Mus musculus : Pspn (persephin) MGI
Rattus norvegicus : Pspn (persephin)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	19	6,299,395 - 6,299,950	-	NCBI
Human Genome Assembly HuRef	19	6,135,450 - 6,136,005	-	NCBI
Human Genome Assembly GRCh37	19	6,375,305 - 6,375,860	-	NCBI
Human Celera Assembly	19	6,314,092 - 6,314,647	-	NCBI
Human Genome Assembly Build 36	19	6,326,305 - 6,326,860	-	NCBI
Human Cytogenetic Map	19	p13.3		NCBI
Human Genome Assembly	19	6,326,304 - 6,326,860		NCBI