Adcy5 (adenylate cyclase 5) - Rat Genome Database

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Gene: Adcy5 (adenylate cyclase 5) Mus musculus
Analyze
Symbol: Adcy5
Name: adenylate cyclase 5
RGD ID: 736883
MGI Page MGI
Description: Enables adenylate cyclase activity; adenylate cyclase binding activity; and scaffold protein binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway; locomotory behavior; and neuromuscular process controlling balance. Located in cilium and plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study Parkinson's disease. Orthologous to human ADCY5 (adenylate cyclase 5).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AC; Ac5; adenylate cyclase type 5; adenylate cyclase type V; adenylyl cyclase 5; ATP pyrophosphate-lyase 5; AW121902
RGD Orthologs
Human
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391634,974,933 - 35,126,108 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1634,975,247 - 35,126,108 (+)EnsemblGRCm39 Ensembl
GRCm381635,154,494 - 35,305,743 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,154,877 - 35,305,738 (+)EnsemblGRCm38mm10GRCm38
MGSCv371635,155,722 - 35,304,635 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,074,624 - 35,225,482 (+)NCBIMGSCv36mm8
Celera1635,623,764 - 35,773,605 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1624.71NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,4-methylenedioxymethamphetamine  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-hydroxyphenyl retinamide  (EXP)
6-propyl-2-thiouracil  (ISO)
7,12-dimethyltetraphene  (ISO)
acetamide  (ISO)
acetylcholine  (EXP)
acrylamide  (ISO)
aflatoxin B1  (ISO)
Aflatoxin B2 alpha  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenite(3-)  (EXP)
atrazine  (ISO)
atropine  (EXP)
benzo[a]pyrene  (ISO)
benzo[b]fluoranthene  (EXP)
benzo[e]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calcium atom  (EXP,ISO)
calcium(0)  (EXP,ISO)
cannabidiol  (EXP)
cannabigerol  (EXP)
cantharidin  (EXP)
carbachol  (EXP)
carbon nanotube  (EXP)
CGS-21680  (EXP)
chlordecone  (EXP)
clozapine  (EXP)
colforsin daropate hydrochloride  (EXP)
crocidolite asbestos  (EXP)
decabromodiphenyl ether  (ISO)
dibutyl phthalate  (EXP)
dichlorine  (ISO)
endosulfan  (ISO)
ethanol  (EXP,ISO)
folic acid  (EXP)
formaldehyde  (ISO)
fulvestrant  (ISO)
genistein  (EXP,ISO)
haloperidol  (EXP)
isoprenaline  (EXP)
lipopolysaccharide  (EXP)
magnesium atom  (ISO)
methapyrilene  (ISO)
monosodium L-glutamate  (ISO)
nitrofen  (ISO)
O-methyleugenol  (ISO)
ozone  (ISO)
paraquat  (ISO)
phenylephrine  (EXP)
PhIP  (ISO)
pioglitazone  (EXP)
progesterone  (ISO)
quinpirole  (EXP)
SCH 23390  (EXP)
silicon dioxide  (ISO)
SKF 38393  (EXP)
sodium arsenite  (ISO)
sulpiride  (EXP)
sunitinib  (ISO)
triclosan  (ISO)
tropan-3alpha-yl 3-hydroxy-2-phenylpropanoate  (EXP)
valproic acid  (ISO)
XL147  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell projection  (IEA)
cilium  (IDA)
endosome  (ISO)
membrane  (IDA,ISO)
plasma membrane  (IBA,IDA,TAS)
sarcolemma  (ISO)

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Effect of beta-adrenoceptor antagonist and angiotensin-converting enzyme inhibitor on hypertension-associated changes in adenylyl cyclase type V messenger RNA expression in spontaneously hypertensive rats. Fujino T, etal., J Cardiovasc Pharmacol. 2003 May;41(5):720-5.
2. Cellular localization of type 5 and type 6 ACs in collecting duct and regulation of cAMP synthesis. Helies-Toussaint C, etal., Am J Physiol Renal Physiol. 2000 Jul;279(1):F185-94.
3. KEGG: Kyoto Encyclopedia of Genes and Genomes KEGG
4. Glucagon-mediated internalization of serine-phosphorylated glucagon receptor and Gsalpha in rat liver. Merlen C, etal., FEBS Lett. 2006 Oct 16;580(24):5697-704. Epub 2006 Sep 20.
5. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
6. MGDs mouse GO annotations MGD data from the GO Consortium
7. MGD IEA MGD IEA
8. Sensing Positive versus Negative Reward Signals through Adenylyl Cyclase-Coupled GPCRs in Direct and Indirect Pathway Striatal Medium Spiny Neurons. Nair AG, etal., J Neurosci. 2015 Oct 14;35(41):14017-30. doi: 10.1523/JNEUROSCI.0730-15.2015.
9. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
10. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
11. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
12. Increased expression of adenylyl cyclase isoforms in the adrenal gland of diabetic Goto-Kakizaki rat. Portela-Gomes GM, etal., Appl Immunohistochem Mol Morphol. 2002 Dec;10(4):387-92.
13. Two members of a widely expressed subfamily of hormone-stimulated adenylyl cyclases. Premont RT, etal., Proc Natl Acad Sci U S A 1992 Oct 15;89(20):9809-13.
14. Mouse MP Annotation Import Pipeline RGD automated import pipeline
15. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
16. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
17. Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies. Sadana R and Dessauer CW, Neurosignals. 2009;17(1):5-22. Epub 2008 Oct 24.
Additional References at PubMed
PMID:7766992   PMID:8889548   PMID:9611134   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12223546   PMID:12297500   PMID:12466851   PMID:12477932   PMID:12613887  
PMID:12665504   PMID:12869393   PMID:12904575   PMID:14681479   PMID:15094058   PMID:15262973   PMID:15489334   PMID:16141072   PMID:16141073   PMID:16537460   PMID:16615126   PMID:17068292  
PMID:17110384   PMID:17114649   PMID:17190869   PMID:17229090   PMID:17410641   PMID:17557924   PMID:17567809   PMID:17593019   PMID:17662940   PMID:17893275   PMID:18164588   PMID:18450980  
PMID:18673448   PMID:18971482   PMID:19106458   PMID:19307450   PMID:19405150   PMID:19574217   PMID:19734365   PMID:19793969   PMID:19889965   PMID:20189959   PMID:20431059   PMID:20443853  
PMID:20709863   PMID:21193983   PMID:21282557   PMID:21670265   PMID:21677750   PMID:21873635   PMID:22250198   PMID:23020244   PMID:23063718   PMID:23104867   PMID:23536361   PMID:23609114  
PMID:23840883   PMID:23957304   PMID:24944202   PMID:25164669   PMID:25193472   PMID:25378213   PMID:25485900   PMID:25677623   PMID:25732192   PMID:25793868   PMID:26023182   PMID:26424149  
PMID:26613416   PMID:26930384   PMID:27117748   PMID:27826057   PMID:27878759   PMID:28887652   PMID:29042084   PMID:29694437   PMID:29800555   PMID:30562941   PMID:31009605   PMID:31162142  
PMID:31173603   PMID:32212159   PMID:32229518   PMID:32325033   PMID:32488198   PMID:32702291   PMID:32957635   PMID:33082339   PMID:33919448   PMID:36539102  


Genomics

Comparative Map Data
Adcy5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391634,974,933 - 35,126,108 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1634,975,247 - 35,126,108 (+)EnsemblGRCm39 Ensembl
GRCm381635,154,494 - 35,305,743 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1635,154,877 - 35,305,738 (+)EnsemblGRCm38mm10GRCm38
MGSCv371635,155,722 - 35,304,635 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361635,074,624 - 35,225,482 (+)NCBIMGSCv36mm8
Celera1635,623,764 - 35,773,605 (+)NCBICelera
Cytogenetic Map16B3NCBI
cM Map1624.71NCBI
ADCY5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383123,282,296 - 123,449,090 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl3123,282,296 - 123,449,090 (-)EnsemblGRCh38hg38GRCh38
GRCh373123,001,143 - 123,167,937 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363124,486,089 - 124,650,082 (-)NCBINCBI36Build 36hg18NCBI36
Build 343124,486,088 - 124,650,082NCBI
Celera3121,410,492 - 121,574,947 (-)NCBICelera
Cytogenetic Map3q21.1ENTREZGENE
HuRef3120,374,350 - 120,540,687 (-)NCBIHuRef
CHM1_13122,964,827 - 123,131,019 (-)NCBICHM1_1
T2T-CHM13v2.03126,002,377 - 126,169,667 (-)NCBIT2T-CHM13v2.0
Adcy5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81178,976,861 - 79,123,343 (-)NCBIGRCr8
mRatBN7.21165,471,612 - 65,618,877 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1165,471,612 - 65,618,974 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1174,293,894 - 74,441,081 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01166,956,169 - 67,103,380 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01165,987,453 - 66,134,656 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01168,695,839 - 68,842,452 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1168,695,839 - 68,842,320 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01171,787,104 - 71,933,971 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41167,290,968 - 67,437,468 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11167,348,556 - 67,495,057 (-)NCBI
Celera1164,930,432 - 65,076,790 (-)NCBICelera
Cytogenetic Map11q22NCBI
ADCY5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22121,235,483 - 121,402,587 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan13121,241,907 - 121,407,362 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v03120,380,094 - 120,545,725 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.13127,281,603 - 127,446,504 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3127,283,921 - 127,446,508 (-)Ensemblpanpan1.1panPan2
ADCY5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13326,345,617 - 26,490,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3326,345,617 - 26,504,616 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3326,367,988 - 26,513,164 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03326,577,319 - 26,724,145 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3326,578,830 - 26,724,145 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13326,374,397 - 26,519,530 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03326,418,883 - 26,564,205 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03326,977,815 - 27,020,671 (-)NCBIUU_Cfam_GSD_1.0
Adcy5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602127,842,824 - 127,989,489 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367251,751,266 - 1,897,946 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367251,751,272 - 1,897,937 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADCY5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13136,972,801 - 137,135,347 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113136,965,746 - 137,133,795 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213146,590,223 - 146,680,465 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADCY5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12257,427,711 - 57,589,440 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041108,759,225 - 108,922,808 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Adcy5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249121,632,107 - 1,768,462 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249121,632,469 - 1,767,885 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Adcy5
4055 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:984
Count of miRNA genes:532
Interacting mature miRNAs:660
Transcripts:ENSMUST00000114913
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
27095908Scvln7_msacral vertebrae length 2, 5 week (mouse)16331786439820362Mouse
27226768Tibl9_mtibia length 9, 5 week (mouse)16331786451420363Mouse
27226785Feml12_mfemur length 12, 5 week (mouse)16331786464620363Mouse
26884432Zlq7_mzygomatic length QTL 7, 10 week (mouse)16381786464620363Mouse
38501069Tip4_mtuberculosis immunophenotype 4, IFN-g level (mouse)16431786444520363Mouse
1301443Mopkd2_mmodifier of polycystic kidney disease progression 2 (mouse)Not determined16464631438646414Mouse
1300656Bgeq15_mbody growth early QTL 15 (mouse)Not determined16577525239775440Mouse
1301945Skl7_mskeletal size (tail length) 7 (mouse)Not determined16577525239775440Mouse
1300943Skts9_mskin tumor susceptibility 9 (mouse)Not determined16577525239775440Mouse
1300987Skull23_mskull morphology 23 (mouse)Not determined16577525239775440Mouse
4141010Bbq1_mbrain and behavior QTL 1 (mouse)Not determined16647700935021216Mouse
1357763Lp1_mlymphocyte proliferation 1 (mouse)Not determined16654297965466552Mouse
11251724Ewc6_methanol withdrawal and consumption 6 (mouse)16822605242226052Mouse
26884376Skwq4_mskull length QTL 4, 5 week (mouse)16841786490896888Mouse
10043978Obq35_mobesity QTL 35 (mouse)Not determined16988163143881631Mouse
1301086Lprm5_mlymphoproliferation modifier 5 (mouse)Not determined161184882445848923Mouse
1301841Lrnx9_mlearning-contextual 9 (mouse)Not determined161222536046225471Mouse
10045614Rapop6_mradiation-induced apoptosis 6 (mouse)Not determined161480292148803032Mouse
4142236Pstc4_mperiosteal circumference 4 (mouse)Not determined161552290949523112Mouse
1357517Bwtn1_mbody weight at necropsy 1 (mouse)Not determined162001932985600826Mouse
1300534Bmd15_mbone mineral density 15 (mouse)Not determined162193838355938574Mouse
4141179Ipng3_mimprinted postnatal growth 3 (mouse)Not determined2277525257594076Mouse
15092062Egrme4_mearly growth rate, maternal effect 4 (mouse)162521866444220250Mouse
11059559Lmr12a_mleishmaniasis resistance 12a (mouse)162879281362792952Mouse
11059560Lmr12b_mleishmaniasis resistance 12b (mouse)162879281362792952Mouse
11049571Lmr12c_mleishmaniasis resistance 12c (mouse)162879281362792952Mouse
1300915Lmr12_mleishmaniasis resistance 12 (mouse)Not determined162879281362792952Mouse
25671380Hrsq2_mhost response to SARS QTL 2, titer (mouse)163140250136540273Mouse
1301070Cypr1_mcytokine production 1 (mouse)Not determined163231279566312933Mouse
4142187Arrd3_mage-related retinal degeneration 3 (mouse)Not determined3252290965466552Mouse

Markers in Region
AW121902  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381635,305,481 - 35,305,627UniSTSGRCm38
MGSCv371635,305,567 - 35,305,713UniSTSGRCm37
Celera1635,774,537 - 35,774,683UniSTS
Cytogenetic Map16B-5UniSTS
Whitehead/MRC_RH16336.85UniSTS
D16Mit167  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381635,200,724 - 35,200,846UniSTSGRCm38
MGSCv371635,200,810 - 35,200,932UniSTSGRCm37
Celera1635,669,027 - 35,669,149UniSTS
Cytogenetic Map16B-5UniSTS
cM Map1626.5UniSTS
Whitehead Genetic1625.1UniSTS
Whitehead_YAC16 UniSTS
Adcy5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381635,304,192 - 35,304,339UniSTSGRCm38
MGSCv371635,304,278 - 35,304,425UniSTSGRCm37
Celera1635,773,248 - 35,773,395UniSTS
Cytogenetic Map16B-5UniSTS
cM Map16 UniSTS


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000114913   ⟹   ENSMUSP00000110563
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1634,975,247 - 35,126,108 (+)Ensembl
GRCm38.p6 Ensembl1635,154,877 - 35,305,738 (+)Ensembl
RefSeq Acc Id: ENSMUST00000232470
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1635,091,032 - 35,092,487 (+)Ensembl
GRCm38.p6 Ensembl1635,270,662 - 35,272,117 (+)Ensembl
RefSeq Acc Id: NM_001012765   ⟹   NP_001012783
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391634,975,251 - 35,126,108 (+)NCBI
GRCm381635,154,864 - 35,305,743 (+)NCBI
MGSCv371635,155,722 - 35,304,635 (+)RGD
Celera1635,623,764 - 35,773,605 (+)RGD
cM Map16 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001417055   ⟹   NP_001403984
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391634,974,933 - 35,126,108 (+)NCBI
RefSeq Acc Id: NM_001417056   ⟹   NP_001403985
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391634,975,251 - 35,126,108 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_001012783   ⟸   NM_001012765
- Peptide Label: isoform 1
- UniProtKB: Q3UH09 (UniProtKB/Swiss-Prot),   Q3TU67 (UniProtKB/Swiss-Prot),   Q5BL06 (UniProtKB/Swiss-Prot),   P84309 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000110563   ⟸   ENSMUST00000114913
RefSeq Acc Id: NP_001403984   ⟸   NM_001417055
- Peptide Label: isoform 2
RefSeq Acc Id: NP_001403985   ⟸   NM_001417056
- Peptide Label: isoform 3
Protein Domains
Guanylate cyclase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P84309-F1-model_v2 AlphaFold P84309 1-1262 view protein structure

Promoters
RGD ID:6826749
Promoter ID:MM_KWN:20865
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Spleen
Transcripts:ENSMUST00000023549,   ENSMUST00000114913
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361635,154,596 - 35,157,027 (+)MPROMDB
RGD ID:8686070
Promoter ID:EPDNEW_M21066
Type:multiple initiation site
Name:Adcy5_1
Description:Mus musculus adenylate cyclase 5 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381635,155,539 - 35,155,599EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99673 AgrOrtholog
Ensembl Genes ENSMUSG00000022840 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000114913 ENTREZGENE
  ENSMUST00000114913.3 UniProtKB/Swiss-Prot
Gene3D-CATH 3.30.70.1230 UniProtKB/Swiss-Prot
InterPro A/G_cyclase UniProtKB/Swiss-Prot
  A/G_cyclase_CS UniProtKB/Swiss-Prot
  AC_N UniProtKB/Swiss-Prot
  Adcy UniProtKB/Swiss-Prot
  Adcy_conserved_dom UniProtKB/Swiss-Prot
  Nucleotide_cyclase UniProtKB/Swiss-Prot
KEGG Report mmu:224129 UniProtKB/Swiss-Prot
MGD MGI:99673 ENTREZGENE
NCBI Gene 224129 ENTREZGENE
PANTHER ADENYLATE CYCLASE TYPE 1 UniProtKB/Swiss-Prot
  ADENYLATE CYCLASE TYPE 5 UniProtKB/Swiss-Prot
Pfam AC_N UniProtKB/Swiss-Prot
  DUF1053 UniProtKB/Swiss-Prot
  Guanylate_cyc UniProtKB/Swiss-Prot
PhenoGen Adcy5 PhenoGen
PIRSF Ade_cyc UniProtKB/Swiss-Prot
PROSITE GUANYLATE_CYCLASE_1 UniProtKB/Swiss-Prot
  GUANYLATE_CYCLASE_2 UniProtKB/Swiss-Prot
SMART CYCc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF55073 UniProtKB/Swiss-Prot
UniProt ADCY5_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TQH8_MOUSE UniProtKB/TrEMBL
  Q3TU67 ENTREZGENE
  Q3UH09 ENTREZGENE
  Q5BL06 ENTREZGENE
UniProt Secondary Q3TU67 UniProtKB/Swiss-Prot
  Q3UH09 UniProtKB/Swiss-Prot
  Q5BL06 UniProtKB/Swiss-Prot