Gene: RHD (Rh blood group, D antigen)  Homo sapiens

Symbol: RHD
Name: Rh blood group, D antigen
Description: The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: blood group Rh(D) polypeptide; CD240D; D antigen (DCS); DIIIc; MGC165007; OTTHUMP00000003536; OTTHUMP00000211878; RH; Rh blood group antigen Evans; Rh blood group, D anitgen; RH polypeptide 2; RH30; Rh4; RHCED; RhDCw; RHDel; RHDVA(TT); rhesus blood group; Rhesus blood group D antigen allele DIII type 7; rhesus D antigen; Rhesus system D polypeptide; RhII; RhK562-II; RhPI; RHPII; RHXIII
Orthologs: Mus musculus : Rhd (Rh blood group, D antigen)  MGI
Rattus norvegicus : Rhd (Rh blood group, D antigen)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1125,811,919 - 25,869,963+NCBI
Human Genome Assembly HuRef123,853,045 - 23,910,998+NCBI
Human Genome Assembly GRCh37125,598,981 - 25,656,936+NCBI
Human Genome Assembly Build 36125,471,568 - 25,529,523+NCBI
Human Cytogenetic Map1p36.11 NCBI
Human Genome Assembly125,344,320 - 25,402,252 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on RHD
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 736735
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-04-02
Status: ACTIVE