Gene: SCN3A (sodium voltage-gated channel alpha subunit 3) Homo sapiens
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Symbol: SCN3A
Name: sodium voltage-gated channel alpha subunit 3
Description: Voltage-gated sodium channels are transmembrane glycoprotein complexes composed of a large alpha subunit with 24 transmembrane domains and one or more regulatory beta subunits. They are responsible for the generation and propagation of action potentials in neurons and muscle. This gene encodes one member of the sodium channel alpha subunit gene family, and is found in a cluster of five alpha subunit genes on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: brain III voltage-gated sodium channel; KIAA1356; NAC3; Nav1.3; OTTHUMP00000041047; OTTHUMP00000041048; OTTHUMP00000204827; sodium channel protein brain III subunit alpha; sodium channel protein type 3 subunit alpha; sodium channel protein type III subunit alpha; sodium channel, voltage gated, type III alpha subunit; sodium channel, voltage-gated, type III, alpha polypeptide; sodium channel, voltage-gated, type III, alpha subunit; voltage-gated sodium channel subtype III; voltage-gated sodium channel subunit alpha Nav1.3
Orthologs:
Mus musculus (house mouse) : Scn3a (sodium channel, voltage-gated, type III, alpha)  MGI
Rattus norvegicus (Norway rat) : Scn3a (sodium voltage-gated channel alpha subunit 3)
Chinchilla lanigera (long-tailed chinchilla) : Scn3a (sodium voltage-gated channel alpha subunit 3)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN3A (sodium voltage-gated channel alpha subunit 3)
Canis lupus familiaris (dog) : SCN3A (sodium voltage-gated channel alpha subunit 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn3a (sodium voltage-gated channel alpha subunit 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382165,087,520 - 165,204,295 (-)NCBIGRCh38hg38GRCh38
GRCh372165,944,030 - 166,060,577 (-)NCBIGRCh37hg19GRCh37
Build 362165,652,276 - 165,768,823 (-)NCBINCBI36hg18NCBI36
Build 342165,769,546 - 165,886,060NCBI
Celera2159,554,632 - 159,671,179 (-)NCBI
Cytogenetic Map2q24.3NCBImapview
HuRef2157,826,522 - 157,942,999 (-)NCBI
CHM1_12165,949,962 - 166,066,539 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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Genomics

Comparative Map Data
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miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
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Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on SCN3A
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
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RGD Object Information
RGD ID: 736601
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2017-09-05
Status: ACTIVE