ADD2 (adducin 2) - Rat Genome Database

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Gene: ADD2 (adducin 2) Homo sapiens
Analyze
Symbol: ADD2
Name: adducin 2
RGD ID: 736575
HGNC Page HGNC:244
Description: Enables cytoskeletal protein binding activity; protein dimerization activity; and protein kinase binding activity. Involved in several processes, including actin filament bundle assembly; barbed-end actin filament capping; and leukocyte tethering or rolling. Located in cytoplasmic vesicle and plasma membrane raft. Part of F-actin capping protein complex. Implicated in IgA glomerulonephritis and hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: ADDB; adducin 2 (beta); adducin 2, beta; beta adducin; beta-adducin; erythrocyte adducin subunit beta
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38270,656,784 - 70,768,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl270,607,618 - 70,768,225 (-)EnsemblGRCh38hg38GRCh38
GRCh37270,883,916 - 70,995,332 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36270,742,770 - 70,848,837 (-)NCBINCBI36Build 36hg18NCBI36
Build 34270,800,919 - 70,906,984NCBI
Celera270,739,895 - 70,846,052 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef270,626,283 - 70,732,257 (-)NCBIHuRef
CHM1_1270,818,535 - 70,924,705 (-)NCBICHM1_1
T2T-CHM13v2.0270,667,847 - 70,779,251 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. The genetic association database. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
2. alpha- and beta-Adducin polymorphisms affect podocyte proteins and proteinuria in rodents and decline of renal function in human IgA nephropathy. Ferrandi M, etal., J Mol Med (Berl). 2010 Feb;88(2):203-17. Epub 2009 Oct 17.
3. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
4. Primary structure and domain organization of human alpha and beta adducin. Joshi R, etal., J Cell Biol 1991 Nov;115(3):665-75.
5. Polymorphisms in four candidate genes in young patients with essential hypertension. Marcun Varda N, etal., Acta Paediatr. 2006 Mar;95(3):353-8.
6. Mild spherocytic hereditary elliptocytosis and altered levels of alpha- and gamma-adducins in beta-adducin-deficient mice. Muro AF, etal., Blood 2000 Jun 15;95(12):3978-85.
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. [Association and interaction of AGT, AGTR1, ACE, ADRB2, DRD1, ADD1, ADD2, ATP2B1, TBXA2R and PTGS2 genes on the risk of hypertension in Antioquian population]. Valencia DM, etal., Biomedica. 2013 Oct-Dec;33(4):598-614.
Additional References at PubMed
PMID:3693401   PMID:7490111   PMID:7642559   PMID:7707875   PMID:7999065   PMID:8563174   PMID:8566798   PMID:8619474   PMID:8626479   PMID:8810272   PMID:8889549   PMID:9110174  
PMID:9244430   PMID:9679146   PMID:10485892   PMID:11526103   PMID:12427140   PMID:12477932   PMID:12653680   PMID:12951058   PMID:14517477   PMID:14553963   PMID:15146197   PMID:15345747  
PMID:15489334   PMID:15528469   PMID:15716695   PMID:15815621   PMID:15834281   PMID:15963851   PMID:16105548   PMID:16116087   PMID:16344560   PMID:17301826   PMID:17854487   PMID:18003638  
PMID:18347014   PMID:18667944   PMID:18787518   PMID:18959617   PMID:19460752   PMID:19913121   PMID:20379614   PMID:20628086   PMID:21606488   PMID:21697133   PMID:21832049   PMID:21873635  
PMID:24129186   PMID:24927181   PMID:25425738   PMID:26045217   PMID:26186194   PMID:26723519   PMID:27493446   PMID:27880917   PMID:28514442   PMID:29568061   PMID:29778605   PMID:29901076  
PMID:30196744   PMID:30442766   PMID:30463901   PMID:30639242   PMID:31586073   PMID:31871319   PMID:32707033   PMID:33957083   PMID:33961781   PMID:34079125   PMID:35256949   PMID:35271311  
PMID:35337019   PMID:35384245   PMID:35446349   PMID:36215168   PMID:37827155  


Genomics

Comparative Map Data
ADD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38270,656,784 - 70,768,200 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl270,607,618 - 70,768,225 (-)EnsemblGRCh38hg38GRCh38
GRCh37270,883,916 - 70,995,332 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36270,742,770 - 70,848,837 (-)NCBINCBI36Build 36hg18NCBI36
Build 34270,800,919 - 70,906,984NCBI
Celera270,739,895 - 70,846,052 (-)NCBICelera
Cytogenetic Map2p13.3NCBI
HuRef270,626,283 - 70,732,257 (-)NCBIHuRef
CHM1_1270,818,535 - 70,924,705 (-)NCBICHM1_1
T2T-CHM13v2.0270,667,847 - 70,779,251 (-)NCBIT2T-CHM13v2.0
Add2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39686,005,663 - 86,101,391 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl686,005,663 - 86,101,391 (+)EnsemblGRCm39 Ensembl
GRCm38686,028,681 - 86,124,409 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl686,028,681 - 86,124,409 (+)EnsemblGRCm38mm10GRCm38
MGSCv37686,028,078 - 86,069,549 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36686,043,718 - 86,085,189 (+)NCBIMGSCv36mm8
Celera688,013,744 - 88,055,678 (+)NCBICelera
Cytogenetic Map6C3- D1NCBI
cM Map637.55NCBI
Add2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84120,001,977 - 120,101,090 (+)NCBIGRCr8
mRatBN7.24118,444,594 - 118,538,505 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4118,497,416 - 118,538,505 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4123,971,536 - 124,012,678 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04119,746,277 - 119,787,417 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04118,370,290 - 118,411,423 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04117,691,294 - 117,887,556 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4117,743,710 - 117,882,464 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04182,417,932 - 182,454,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44120,221,140 - 120,275,351 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14120,465,620 - 120,510,931 (+)NCBI
Celera4107,471,489 - 107,504,523 (+)NCBICelera
Cytogenetic Map4q34NCBI
Add2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542414,411,124 - 14,517,813 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542414,411,279 - 14,517,813 (+)NCBIChiLan1.0ChiLan1.0
ADD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21255,621,219 - 55,732,515 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A55,625,166 - 55,736,459 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A70,724,454 - 70,831,248 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A71,839,470 - 71,944,537 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A71,839,470 - 71,895,106 (-)Ensemblpanpan1.1panPan2
ADD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11069,056,367 - 69,098,775 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1069,057,267 - 69,098,521 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1068,939,411 - 69,031,911 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01070,074,115 - 70,166,872 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1070,077,064 - 70,166,770 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11069,792,050 - 69,885,391 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01070,054,471 - 70,147,033 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01070,356,179 - 70,411,965 (-)NCBIUU_Cfam_GSD_1.0
Add2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629213,599,879 - 13,714,530 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649114,862,531 - 14,971,329 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649114,856,764 - 14,971,161 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl371,730,003 - 71,840,861 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1371,729,882 - 71,845,761 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2375,131,802 - 75,191,268 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11436,343,978 - 36,450,685 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1436,344,022 - 36,449,315 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604575,565,751 - 75,677,689 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Add2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247622,674,620 - 2,726,587 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247622,619,371 - 2,726,586 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ADD2
27 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001617.3(ADD2):c.1881G>A (p.Lys627=) single nucleotide variant Malignant melanoma [RCV000065654] Chr2:70663725 [GRCh38]
Chr2:70890857 [GRCh37]
Chr2:70744365 [NCBI36]
Chr2:2p13.3		 not provided
NM_001617.3(ADD2):c.7G>A (p.Glu3Lys) single nucleotide variant Malignant melanoma [RCV000065655] Chr2:70706402 [GRCh38]
Chr2:70933534 [GRCh37]
Chr2:70787042 [NCBI36]
Chr2:2p13.3		 not provided
GRCh38/hg38 2p13.3-13.2(chr2:70709155-72346899)x3 copy number gain See cases [RCV000133956] Chr2:70709155..72346899 [GRCh38]
Chr2:70936287..72574028 [GRCh37]
Chr2:70789795..72427536 [NCBI36]
Chr2:2p13.3-13.2		 uncertain significance
GRCh38/hg38 2p16.1-11.2(chr2:58279519-83586962)x3 copy number gain See cases [RCV000136053] Chr2:58279519..83586962 [GRCh38]
Chr2:58506654..83814086 [GRCh37]
Chr2:58360158..83667597 [NCBI36]
Chr2:2p16.1-11.2		 pathogenic
GRCh38/hg38 2p16.3-11.2(chr2:47620388-86702722)x3 copy number gain See cases [RCV000137586] Chr2:47620388..86702722 [GRCh38]
Chr2:47847527..86929845 [GRCh37]
Chr2:47701031..86783356 [NCBI36]
Chr2:2p16.3-11.2		 uncertain significance
GRCh38/hg38 2p25.1-11.2(chr2:7495123-87705899)x3 copy number gain See cases [RCV000141494] Chr2:7495123..87705899 [GRCh38]
Chr2:7635254..88005418 [GRCh37]
Chr2:7552705..87786533 [NCBI36]
Chr2:2p25.1-11.2		 benign
GRCh37/hg19 2p25.3-q37.3(chr2:14238-243048760)x3 copy number gain not provided [RCV000752802] Chr2:14238..243048760 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p15-11.2(chr2:62245236-86978895)x3 copy number gain See cases [RCV000448688] Chr2:62245236..86978895 [GRCh37]
Chr2:2p15-11.2		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384) copy number gain See cases [RCV000512056] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:12771-242783384)x3 copy number gain See cases [RCV000511212] Chr2:12771..242783384 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NM_001617.4(ADD2):c.325G>A (p.Val109Ile) single nucleotide variant Inborn genetic diseases [RCV003249921] Chr2:70696394 [GRCh38]
Chr2:70923526 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1063A>C (p.Met355Leu) single nucleotide variant Inborn genetic diseases [RCV003274726] Chr2:70683653 [GRCh38]
Chr2:70910785 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.193G>C (p.Glu65Gln) single nucleotide variant Inborn genetic diseases [RCV003295149] Chr2:70704450 [GRCh38]
Chr2:70931582 [GRCh37]
Chr2:2p13.3		 uncertain significance
Single allele duplication not provided [RCV000677942] Chr2:63671346..85698002 [GRCh37]
Chr2:2p15-11.2		 pathogenic
Single allele deletion not provided [RCV000714264] Chr2:40608411..146900718 [GRCh37]
Chr2:2p22.1-q22.3		 likely pathogenic
GRCh37/hg19 2p25.3-q37.3(chr2:15672-243101834)x3 copy number gain not provided [RCV000752804] Chr2:15672..243101834 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NM_001617.4(ADD2):c.50G>A (p.Gly17Glu) single nucleotide variant not provided [RCV000881979] Chr2:70706359 [GRCh38]
Chr2:70933491 [GRCh37]
Chr2:2p13.3		 benign
NM_001617.4(ADD2):c.82G>A (p.Asp28Asn) single nucleotide variant not provided [RCV000965604] Chr2:70706327 [GRCh38]
Chr2:70933459 [GRCh37]
Chr2:2p13.3		 benign
NM_001617.4(ADD2):c.1005G>T (p.Glu335Asp) single nucleotide variant not provided [RCV000964863] Chr2:70683711 [GRCh38]
Chr2:70910843 [GRCh37]
Chr2:2p13.3		 benign
GRCh37/hg19 2p25.3-q37.3(chr2:1-243199373) copy number gain Mosaic trisomy 2 [RCV002280628] Chr2:1..243199373 [GRCh37]
Chr2:2p25.3-q37.3		 pathogenic
NC_000002.11:g.(?_69240632)_(74779761_?)dup duplication not provided [RCV003122858] Chr2:69240632..74779761 [GRCh37]
Chr2:2p13.3-13.1		 uncertain significance
Single allele duplication not specified [RCV002286373] Chr2:69512973..71153026 [GRCh38]
Chr2:2p13.3		 uncertain significance
GRCh37/hg19 2p25.1-q13(chr2:11504318-111365996)x1 copy number loss See cases [RCV002287563] Chr2:11504318..111365996 [GRCh37]
Chr2:2p25.1-q13		 pathogenic
NM_001617.4(ADD2):c.425G>A (p.Arg142Gln) single nucleotide variant Inborn genetic diseases [RCV002685247] Chr2:70696294 [GRCh38]
Chr2:70923426 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1931C>T (p.Pro644Leu) single nucleotide variant Inborn genetic diseases [RCV002683672] Chr2:70663675 [GRCh38]
Chr2:70890807 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.736G>A (p.Val246Ile) single nucleotide variant Inborn genetic diseases [RCV002946834] Chr2:70690899 [GRCh38]
Chr2:70918031 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.2080C>G (p.Pro694Ala) single nucleotide variant Inborn genetic diseases [RCV002912098] Chr2:70663526 [GRCh38]
Chr2:70890658 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.449C>T (p.Ala150Val) single nucleotide variant Inborn genetic diseases [RCV002892431] Chr2:70696270 [GRCh38]
Chr2:70923402 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1256T>G (p.Leu419Arg) single nucleotide variant Inborn genetic diseases [RCV002803396] Chr2:70678831 [GRCh38]
Chr2:70905963 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.338C>T (p.Thr113Met) single nucleotide variant Inborn genetic diseases [RCV002941826] Chr2:70696381 [GRCh38]
Chr2:70923513 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1244C>T (p.Pro415Leu) single nucleotide variant Inborn genetic diseases [RCV002714362] Chr2:70678843 [GRCh38]
Chr2:70905975 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1399G>A (p.Glu467Lys) single nucleotide variant Inborn genetic diseases [RCV002813192] Chr2:70677862 [GRCh38]
Chr2:70904994 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1903G>A (p.Ala635Thr) single nucleotide variant Inborn genetic diseases [RCV002675261] Chr2:70663703 [GRCh38]
Chr2:70890835 [GRCh37]
Chr2:2p13.3		 likely benign
NM_001617.4(ADD2):c.1534T>A (p.Ser512Thr) single nucleotide variant Inborn genetic diseases [RCV003181312] Chr2:70676855 [GRCh38]
Chr2:70903987 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.55C>T (p.Pro19Ser) single nucleotide variant Inborn genetic diseases [RCV003211564] Chr2:70706354 [GRCh38]
Chr2:70933486 [GRCh37]
Chr2:2p13.3		 uncertain significance
GRCh37/hg19 2p14-13.3(chr2:65296579-71305638)x1 copy number loss not provided [RCV003223077] Chr2:65296579..71305638 [GRCh37]
Chr2:2p14-13.3		 uncertain significance
NM_001617.4(ADD2):c.1033G>C (p.Val345Leu) single nucleotide variant Inborn genetic diseases [RCV003304523] Chr2:70683683 [GRCh38]
Chr2:70910815 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.661G>A (p.Asp221Asn) single nucleotide variant Inborn genetic diseases [RCV003265984] Chr2:70692447 [GRCh38]
Chr2:70919579 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1686C>G (p.Asp562Glu) single nucleotide variant Inborn genetic diseases [RCV003342542] Chr2:70674733 [GRCh38]
Chr2:70901865 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.695C>G (p.Ala232Gly) single nucleotide variant Inborn genetic diseases [RCV003373698] Chr2:70692413 [GRCh38]
Chr2:70919545 [GRCh37]
Chr2:2p13.3		 uncertain significance
NM_001617.4(ADD2):c.1896C>T (p.Ser632=) single nucleotide variant not provided [RCV003427006] Chr2:70663710 [GRCh38]
Chr2:70890842 [GRCh37]
Chr2:2p13.3		 likely benign
NM_001617.4(ADD2):c.1627G>A (p.Glu543Lys) single nucleotide variant not provided [RCV003427007] Chr2:70674792 [GRCh38]
Chr2:70901924 [GRCh37]
Chr2:2p13.3		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:7650
Count of miRNA genes:1461
Interacting mature miRNAs:2014
Transcripts:ENST00000264436, ENST00000355733, ENST00000403045, ENST00000407644, ENST00000413157, ENST00000415348, ENST00000425976, ENST00000430656, ENST00000447731, ENST00000456320, ENST00000473232, ENST00000481675, ENST00000496178, ENST00000522886
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
WI-4105  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,978,539 - 70,978,795UniSTSGRCh37
Build 36270,832,047 - 70,832,303RGDNCBI36
Celera270,829,218 - 70,829,474RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,715,607 - 70,715,863UniSTS
Whitehead-RH Map2292.9UniSTS
WI-13671  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,902,230 - 70,902,358UniSTSGRCh37
Build 36270,755,738 - 70,755,866RGDNCBI36
Celera270,752,904 - 70,753,032RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,639,294 - 70,639,422UniSTS
GeneMap99-GB4 RH Map2222.59UniSTS
Whitehead-RH Map2293.0UniSTS
SHGC-142110  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,977,992 - 70,978,315UniSTSGRCh37
Build 36270,831,500 - 70,831,823RGDNCBI36
Celera270,828,671 - 70,828,994RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,715,060 - 70,715,383UniSTS
TNG Radiation Hybrid Map245429.0UniSTS
IB387  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,889,424 - 70,889,575UniSTSGRCh37
Build 36270,742,932 - 70,743,083RGDNCBI36
Celera270,740,103 - 70,740,254RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,626,491 - 70,626,642UniSTS
GeneMap99-GB4 RH Map2224.46UniSTS
Whitehead-RH Map2290.7UniSTS
RH12820  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,889,291 - 70,889,413UniSTSGRCh37
Build 36270,742,799 - 70,742,921RGDNCBI36
Celera270,739,970 - 70,740,092RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,626,358 - 70,626,480UniSTS
GeneMap99-GB4 RH Map2220.18UniSTS
SHGC-30541  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,918,759 - 70,918,885UniSTSGRCh37
Build 36270,772,267 - 70,772,393RGDNCBI36
Celera270,769,433 - 70,769,559RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,655,827 - 70,655,953UniSTS
GeneMap99-G3 RH Map22972.0UniSTS
WI-11693  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,895,642 - 70,895,791UniSTSGRCh37
Build 36270,749,150 - 70,749,299RGDNCBI36
Celera270,746,316 - 70,746,465RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,632,706 - 70,632,855UniSTS
GeneMap99-GB4 RH Map2220.28UniSTS
Whitehead-RH Map2297.2UniSTS
A004B15  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37270,890,164 - 70,890,295UniSTSGRCh37
Build 36270,743,672 - 70,743,803RGDNCBI36
Celera270,740,843 - 70,740,974RGD
Cytogenetic Map2p13.3UniSTS
HuRef270,627,231 - 70,627,362UniSTS
GeneMap99-GB4 RH Map2220.18UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 7 16 28 15 84 16 195 27 1757 20 81 129 5 1 2
Low 1576 892 640 31 1040 16 1302 881 1892 82 927 768 16 862 796 1 1
Below cutoff 788 2082 978 500 681 356 2846 1284 84 259 441 701 152 340 1991 4

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001185054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001185055 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_017482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_017488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011532502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054340427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB593080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC005234 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC007395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF001597 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF038185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF486420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF486421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF486422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF486423 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007372 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK297250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK309773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY660004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC008709 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC010237 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC011416 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC027876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC041666 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC051882 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC056881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC065525 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX119247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471053 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CN428088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068276 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA501584 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  N53078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U43959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000264436   ⟹   ENSP00000264436
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,656,784 - 70,768,200 (-)Ensembl
RefSeq Acc Id: ENST00000355733   ⟹   ENSP00000347972
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,663,483 - 70,768,177 (-)Ensembl
RefSeq Acc Id: ENST00000403045   ⟹   ENSP00000384303
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,607,618 - 70,768,198 (-)Ensembl
RefSeq Acc Id: ENST00000407644   ⟹   ENSP00000384677
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,662,130 - 70,767,715 (-)Ensembl
RefSeq Acc Id: ENST00000413157   ⟹   ENSP00000388072
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,675,093 - 70,768,212 (-)Ensembl
RefSeq Acc Id: ENST00000415348   ⟹   ENSP00000412357
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,692,428 - 70,717,778 (-)Ensembl
RefSeq Acc Id: ENST00000425976   ⟹   ENSP00000412681
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,696,291 - 70,767,469 (-)Ensembl
RefSeq Acc Id: ENST00000430656   ⟹   ENSP00000398112
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,676,403 - 70,768,197 (-)Ensembl
RefSeq Acc Id: ENST00000447731   ⟹   ENSP00000403722
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,706,357 - 70,768,196 (-)Ensembl
RefSeq Acc Id: ENST00000456320   ⟹   ENSP00000414546
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,674,678 - 70,706,408 (-)Ensembl
RefSeq Acc Id: ENST00000473232
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,706,413 - 70,768,200 (-)Ensembl
RefSeq Acc Id: ENST00000481675
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,663,498 - 70,673,348 (-)Ensembl
RefSeq Acc Id: ENST00000496178
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,713,070 - 70,768,225 (-)Ensembl
RefSeq Acc Id: ENST00000522886   ⟹   ENSP00000430243
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl270,673,311 - 70,706,443 (-)Ensembl
RefSeq Acc Id: NM_001185054   ⟹   NP_001171983
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38270,656,784 - 70,767,715 (-)NCBI
GRCh37270,888,334 - 70,995,375 (-)NCBI
HuRef270,626,283 - 70,732,257 (-)ENTREZGENE
CHM1_1270,818,535 - 70,924,177 (-)NCBI
T2T-CHM13v2.0270,667,847 - 70,778,766 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001185055   ⟹   NP_001171984
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38270,675,091 - 70,768,200 (-)NCBI
GRCh37270,888,334 - 70,995,375 (-)NCBI
HuRef270,626,283 - 70,732,257 (-)ENTREZGENE
CHM1_1270,831,534 - 70,924,705 (-)NCBI
T2T-CHM13v2.0270,686,153 - 70,779,251 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001617   ⟹   NP_001608
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38270,656,784 - 70,768,200 (-)NCBI
GRCh37270,888,334 - 70,995,375 (-)NCBI
Build 36270,742,770 - 70,848,837 (-)NCBI Archive
HuRef270,626,283 - 70,732,257 (-)ENTREZGENE
CHM1_1270,818,535 - 70,924,705 (-)NCBI
T2T-CHM13v2.0270,667,847 - 70,779,251 (-)NCBI
Sequence:
RefSeq Acc Id: NM_017482   ⟹   NP_059516
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38270,675,091 - 70,768,200 (-)NCBI
GRCh37270,888,334 - 70,995,375 (-)NCBI
Build 36270,755,731 - 70,848,837 (-)NCBI Archive
HuRef270,626,283 - 70,732,257 (-)ENTREZGENE
CHM1_1270,831,534 - 70,924,705 (-)NCBI
T2T-CHM13v2.0270,686,153 - 70,779,251 (-)NCBI
Sequence:
RefSeq Acc Id: NM_017488   ⟹   NP_059522
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38270,656,784 - 70,768,200 (-)NCBI
GRCh37270,888,334 - 70,995,375 (-)NCBI
Build 36270,742,770 - 70,848,837 (-)NCBI Archive
HuRef270,626,283 - 70,732,257 (-)ENTREZGENE
CHM1_1270,818,535 - 70,924,705 (-)NCBI
T2T-CHM13v2.0270,667,847 - 70,779,251 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011532502   ⟹   XP_011530804
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38270,656,784 - 70,717,748 (-)NCBI
Sequence:
RefSeq Acc Id: XM_054340427   ⟹   XP_054196402
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.0270,667,847 - 70,728,833 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001171983 (Get FASTA)   NCBI Sequence Viewer  
  NP_001171984 (Get FASTA)   NCBI Sequence Viewer  
  NP_001608 (Get FASTA)   NCBI Sequence Viewer  
  NP_059516 (Get FASTA)   NCBI Sequence Viewer  
  NP_059522 (Get FASTA)   NCBI Sequence Viewer  
  XP_011530804 (Get FASTA)   NCBI Sequence Viewer  
  XP_054196402 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA86421 (Get FASTA)   NCBI Sequence Viewer  
  AAD12715 (Get FASTA)   NCBI Sequence Viewer  
  AAD14349 (Get FASTA)   NCBI Sequence Viewer  
  AAH08709 (Get FASTA)   NCBI Sequence Viewer  
  AAH10237 (Get FASTA)   NCBI Sequence Viewer  
  AAH41666 (Get FASTA)   NCBI Sequence Viewer  
  AAH51882 (Get FASTA)   NCBI Sequence Viewer  
  AAH56881 (Get FASTA)   NCBI Sequence Viewer  
  AAH65525 (Get FASTA)   NCBI Sequence Viewer  
  AAP71863 (Get FASTA)   NCBI Sequence Viewer  
  AAP71864 (Get FASTA)   NCBI Sequence Viewer  
  AAP71865 (Get FASTA)   NCBI Sequence Viewer  
  AAP71866 (Get FASTA)   NCBI Sequence Viewer  
  BAD92464 (Get FASTA)   NCBI Sequence Viewer  
  BAF83696 (Get FASTA)   NCBI Sequence Viewer  
  BAG59729 (Get FASTA)   NCBI Sequence Viewer  
  BAJ84020 (Get FASTA)   NCBI Sequence Viewer  
  EAW99798 (Get FASTA)   NCBI Sequence Viewer  
  EAW99799 (Get FASTA)   NCBI Sequence Viewer  
  EAW99800 (Get FASTA)   NCBI Sequence Viewer  
  EAW99801 (Get FASTA)   NCBI Sequence Viewer  
  EAW99802 (Get FASTA)   NCBI Sequence Viewer  
  EAW99803 (Get FASTA)   NCBI Sequence Viewer  
  EAW99804 (Get FASTA)   NCBI Sequence Viewer  
  EAW99805 (Get FASTA)   NCBI Sequence Viewer  
  EAW99806 (Get FASTA)   NCBI Sequence Viewer  
  EAW99807 (Get FASTA)   NCBI Sequence Viewer  
  EAW99808 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000264436
  ENSP00000264436.3
  ENSP00000347972
  ENSP00000347972.3
  ENSP00000384303.2
  ENSP00000384677
  ENSP00000384677.2
  ENSP00000388072
  ENSP00000388072.2
  ENSP00000398112
  ENSP00000398112.1
  ENSP00000403722.1
  ENSP00000412357.1
  ENSP00000412681.1
  ENSP00000414546.3
  ENSP00000430243.1
GenBank Protein P35612 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001608   ⟸   NM_001617
- Peptide Label: isoform a
- UniProtKB: Q7Z690 (UniProtKB/Swiss-Prot),   Q7Z689 (UniProtKB/Swiss-Prot),   Q7Z688 (UniProtKB/Swiss-Prot),   Q6PGQ4 (UniProtKB/Swiss-Prot),   Q6P0P2 (UniProtKB/Swiss-Prot),   Q5U5P4 (UniProtKB/Swiss-Prot),   Q59G82 (UniProtKB/Swiss-Prot),   Q16412 (UniProtKB/Swiss-Prot),   Q13482 (UniProtKB/Swiss-Prot),   D6W5G8 (UniProtKB/Swiss-Prot),   D6W5G7 (UniProtKB/Swiss-Prot),   B4DM17 (UniProtKB/Swiss-Prot),   A8K4P2 (UniProtKB/Swiss-Prot),   Q7Z691 (UniProtKB/Swiss-Prot),   P35612 (UniProtKB/Swiss-Prot),   Q05DK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_059522   ⟸   NM_017488
- Peptide Label: isoform e
- UniProtKB: Q05DK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001171983   ⟸   NM_001185054
- Peptide Label: isoform a
- UniProtKB: Q7Z690 (UniProtKB/Swiss-Prot),   Q7Z689 (UniProtKB/Swiss-Prot),   Q7Z688 (UniProtKB/Swiss-Prot),   Q6PGQ4 (UniProtKB/Swiss-Prot),   Q6P0P2 (UniProtKB/Swiss-Prot),   Q5U5P4 (UniProtKB/Swiss-Prot),   Q59G82 (UniProtKB/Swiss-Prot),   Q16412 (UniProtKB/Swiss-Prot),   Q13482 (UniProtKB/Swiss-Prot),   D6W5G8 (UniProtKB/Swiss-Prot),   D6W5G7 (UniProtKB/Swiss-Prot),   B4DM17 (UniProtKB/Swiss-Prot),   A8K4P2 (UniProtKB/Swiss-Prot),   Q7Z691 (UniProtKB/Swiss-Prot),   P35612 (UniProtKB/Swiss-Prot),   Q05DK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001171984   ⟸   NM_001185055
- Peptide Label: isoform f
- UniProtKB: P35612 (UniProtKB/Swiss-Prot),   Q05DK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_059516   ⟸   NM_017482
- Peptide Label: isoform b
- UniProtKB: P35612 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011530804   ⟸   XM_011532502
- Peptide Label: isoform X1
- UniProtKB: Q7Z690 (UniProtKB/Swiss-Prot),   Q7Z689 (UniProtKB/Swiss-Prot),   Q7Z688 (UniProtKB/Swiss-Prot),   Q6PGQ4 (UniProtKB/Swiss-Prot),   Q6P0P2 (UniProtKB/Swiss-Prot),   Q5U5P4 (UniProtKB/Swiss-Prot),   Q59G82 (UniProtKB/Swiss-Prot),   Q16412 (UniProtKB/Swiss-Prot),   Q13482 (UniProtKB/Swiss-Prot),   D6W5G8 (UniProtKB/Swiss-Prot),   D6W5G7 (UniProtKB/Swiss-Prot),   B4DM17 (UniProtKB/Swiss-Prot),   A8K4P2 (UniProtKB/Swiss-Prot),   Q7Z691 (UniProtKB/Swiss-Prot),   P35612 (UniProtKB/Swiss-Prot),   Q05DK5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000412681   ⟸   ENST00000425976
RefSeq Acc Id: ENSP00000388072   ⟸   ENST00000413157
RefSeq Acc Id: ENSP00000412357   ⟸   ENST00000415348
RefSeq Acc Id: ENSP00000414546   ⟸   ENST00000456320
RefSeq Acc Id: ENSP00000384303   ⟸   ENST00000403045
RefSeq Acc Id: ENSP00000430243   ⟸   ENST00000522886
RefSeq Acc Id: ENSP00000398112   ⟸   ENST00000430656
RefSeq Acc Id: ENSP00000384677   ⟸   ENST00000407644
RefSeq Acc Id: ENSP00000403722   ⟸   ENST00000447731
RefSeq Acc Id: ENSP00000347972   ⟸   ENST00000355733
RefSeq Acc Id: ENSP00000264436   ⟸   ENST00000264436
RefSeq Acc Id: XP_054196402   ⟸   XM_054340427
- Peptide Label: isoform X1
- UniProtKB: Q7Z690 (UniProtKB/Swiss-Prot),   Q7Z689 (UniProtKB/Swiss-Prot),   Q7Z688 (UniProtKB/Swiss-Prot),   Q6PGQ4 (UniProtKB/Swiss-Prot),   Q6P0P2 (UniProtKB/Swiss-Prot),   Q5U5P4 (UniProtKB/Swiss-Prot),   Q59G82 (UniProtKB/Swiss-Prot),   Q16412 (UniProtKB/Swiss-Prot),   Q13482 (UniProtKB/Swiss-Prot),   P35612 (UniProtKB/Swiss-Prot),   D6W5G8 (UniProtKB/Swiss-Prot),   D6W5G7 (UniProtKB/Swiss-Prot),   B4DM17 (UniProtKB/Swiss-Prot),   A8K4P2 (UniProtKB/Swiss-Prot),   Q7Z691 (UniProtKB/Swiss-Prot),   Q05DK5 (UniProtKB/TrEMBL)
Protein Domains
Class II aldolase/adducin N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P35612-F1-model_v2 AlphaFold P35612 1-726 view protein structure

Promoters
RGD ID:6860604
Promoter ID:EPDNEW_H3467
Type:initiation region
Name:ADD2_1
Description:adducin 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38270,768,197 - 70,768,257EPDNEW
RGD ID:6796746
Promoter ID:HG_KWN:33146
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:OTTHUMT00000331313
Position:
Human AssemblyChrPosition (strand)Source
Build 36270,798,186 - 70,798,686 (-)MPROMDB
RGD ID:6797169
Promoter ID:HG_KWN:33147
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   NB4
Transcripts:ENST00000264439,   NM_001185054,   NM_001185055,   NM_017482,   NM_017483,   NM_017484,   NM_017488,   OTTHUMT00000251918,   OTTHUMT00000330123,   OTTHUMT00000331213,   OTTHUMT00000331240,   OTTHUMT00000331241,   OTTHUMT00000331242,   UC002SHA.1,   UC002SHD.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36270,848,176 - 70,848,827 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:244 AgrOrtholog
COSMIC ADD2 COSMIC
Ensembl Genes ENSG00000075340 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000264436 ENTREZGENE
  ENST00000264436.9 UniProtKB/Swiss-Prot
  ENST00000355733 ENTREZGENE
  ENST00000355733.7 UniProtKB/Swiss-Prot
  ENST00000403045.6 UniProtKB/Swiss-Prot
  ENST00000407644 ENTREZGENE
  ENST00000407644.6 UniProtKB/Swiss-Prot
  ENST00000413157 ENTREZGENE
  ENST00000413157.6 UniProtKB/Swiss-Prot
  ENST00000415348.5 UniProtKB/TrEMBL
  ENST00000425976.5 UniProtKB/TrEMBL
  ENST00000430656 ENTREZGENE
  ENST00000430656.5 UniProtKB/Swiss-Prot
  ENST00000447731.6 UniProtKB/TrEMBL
  ENST00000456320.7 UniProtKB/TrEMBL
  ENST00000522886.5 UniProtKB/TrEMBL
Gene3D-CATH 3.40.225.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000075340 GTEx
HGNC ID HGNC:244 ENTREZGENE
Human Proteome Map ADD2 Human Proteome Map
InterPro Aldolase_II/adducin_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Aldolase_II/adducin_N_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:119 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 119 ENTREZGENE
OMIM 102681 OMIM
PANTHER ADDUCIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10672:SF6 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Aldolase_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA24566 PharmGKB
SMART Aldolase_II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF53639 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1C7CYY0_HUMAN UniProtKB/TrEMBL
  A8K4P2 ENTREZGENE
  ADDB_HUMAN UniProtKB/Swiss-Prot
  B4DM17 ENTREZGENE
  C9J080_HUMAN UniProtKB/TrEMBL
  C9J299_HUMAN UniProtKB/TrEMBL
  C9JJK3_HUMAN UniProtKB/TrEMBL
  C9JTM0_HUMAN UniProtKB/TrEMBL
  D6W5G7 ENTREZGENE
  D6W5G8 ENTREZGENE
  P35612 ENTREZGENE
  Q05DK5 ENTREZGENE, UniProtKB/TrEMBL
  Q13482 ENTREZGENE
  Q16412 ENTREZGENE
  Q59G82 ENTREZGENE
  Q5U5P4 ENTREZGENE
  Q6P0P2 ENTREZGENE
  Q6PGQ4 ENTREZGENE
  Q7Z688 ENTREZGENE
  Q7Z689 ENTREZGENE
  Q7Z690 ENTREZGENE
  Q7Z691 ENTREZGENE
UniProt Secondary A8K4P2 UniProtKB/Swiss-Prot
  B4DM17 UniProtKB/Swiss-Prot
  D6W5G7 UniProtKB/Swiss-Prot
  D6W5G8 UniProtKB/Swiss-Prot
  Q13482 UniProtKB/Swiss-Prot
  Q16412 UniProtKB/Swiss-Prot
  Q59G82 UniProtKB/Swiss-Prot
  Q5U5P4 UniProtKB/Swiss-Prot
  Q6P0P2 UniProtKB/Swiss-Prot
  Q6PGQ4 UniProtKB/Swiss-Prot
  Q7Z688 UniProtKB/Swiss-Prot
  Q7Z689 UniProtKB/Swiss-Prot
  Q7Z690 UniProtKB/Swiss-Prot
  Q7Z691 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-01 ADD2  adducin 2    adducin 2 (beta)  Symbol and/or name change 5135510 APPROVED