Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (+)-schisandrin B | multiple interactions | ISO | Neu2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NEU2 mRNA] | CTD | PMID:31150632 | 1,1-dichloroethene | decreases expression | ISO | Neu2 (Mus musculus) | 6480464 | vinylidene chloride results in decreased expression of NEU2 mRNA | CTD | PMID:26682919 | 1,2,4-trimethylbenzene | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | pseudocumene results in increased expression of NEU2 protein | CTD | PMID:17337753 | 1,2-dichloroethane | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | ethylene dichloride results in increased expression of NEU2 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | decreases expression | ISO | Neu2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of NEU2 mRNA | CTD | PMID:22206623 | 17alpha-ethynylestradiol | multiple interactions | ISO | Neu2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NEU2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Neu2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of NEU2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Neu2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NEU2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of NEU2 mRNA | CTD | PMID:21215274 | 2,4,6-trinitrotoluene | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Trinitrotoluene affects the expression of NEU2 mRNA | CTD | PMID:21346803 | 2,4-dinitrotoluene | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | 2 and 4-dinitrotoluene affects the expression of NEU2 mRNA | CTD | PMID:21346803 | 2-hydroxypropanoic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of NEU2 mRNA | CTD | PMID:30851411 | 3H-1,2-dithiole-3-thione | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | 1 and 2-dithiol-3-thione results in decreased expression of NEU2 mRNA | CTD | PMID:19162173 | 4,4'-diaminodiphenylmethane | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of NEU2 mRNA | CTD | PMID:18648102 | 4-hydroxyphenyl retinamide | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | Fenretinide results in increased expression of NEU2 mRNA | CTD | PMID:28973697 | 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of NEU2 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Propylthiouracil affects the expression of NEU2 mRNA | CTD | PMID:19483382 | 6-propyl-2-thiouracil | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of NEU2 mRNA | CTD | PMID:24780913 | amiodarone | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Amiodarone affects the expression of NEU2 mRNA | CTD | PMID:19483382 | ammonium chloride | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of NEU2 mRNA | CTD | PMID:16483693 | benzbromarone | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Benzbromarone affects the expression of NEU2 mRNA | CTD | PMID:19483382 | benzo[a]pyrene | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in decreased expression of NEU2 mRNA | CTD | PMID:21839799 | benzo[a]pyrene | multiple interactions | ISO | Neu2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of NEU2 mRNA | CTD | PMID:27858113 | benzo[a]pyrene | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NEU2 mRNA | CTD | PMID:22228805 | benzo[b]fluoranthene | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of NEU2 mRNA | CTD | PMID:26377693 | benzo[b]fluoranthene | multiple interactions | ISO | Neu2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of NEU2 mRNA | CTD | PMID:27858113 | bisphenol A | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of NEU2 mRNA | CTD | PMID:30816183 and PMID:32528016 | carbon nanotube | decreases expression | ISO | Neu2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to NEU2 gene] | CTD | PMID:28238834 | chrysene | multiple interactions | ISO | Neu2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of NEU2 mRNA | CTD | PMID:27858113 | clofibrate | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Clofibrate affects the expression of NEU2 mRNA | CTD | PMID:19483382 | cobalt dichloride | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | cobaltous chloride results in decreased expression of NEU2 mRNA | CTD | PMID:24386269 | dexamethasone | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Dexamethasone results in decreased expression of NEU2 mRNA | CTD | PMID:20032058 | dexamethasone | multiple interactions | ISO | Neu2 (Rattus norvegicus) | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of NEU2 mRNA] | CTD | PMID:20032058 | ethanol | affects expression | ISO | Neu2 (Mus musculus) | 6480464 | Ethanol affects the expression of NEU2 mRNA | CTD | PMID:30319688 | furan | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | furan results in increased expression of NEU2 mRNA | CTD | PMID:26194646 | graphite | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Graphite affects the expression of NEU2 mRNA | CTD | PMID:29933104 | L-ethionine | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Ethionine affects the expression of NEU2 mRNA | CTD | PMID:19483382 | omeprazole | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Omeprazole affects the expression of NEU2 mRNA | CTD | PMID:19483382 | ozone | multiple interactions | ISO | Neu2 (Mus musculus) | 6480464 | [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of NEU2 mRNA and [Air Pollutants results in increased abundance of Ozone] which results in increased expression of NEU2 mRNA | CTD | PMID:34911549 | p-toluidine | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | 4-toluidine results in increased expression of NEU2 mRNA | CTD | PMID:27638505 | paracetamol | affects expression | ISO | Neu2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of NEU2 mRNA | CTD | PMID:17562736 | pirinixic acid | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | pirinixic acid results in increased expression of NEU2 mRNA | CTD | PMID:19162173 | pirinixic acid | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | pirinixic acid affects the expression of NEU2 mRNA | CTD | PMID:19483382 | pregnenolone 16alpha-carbonitrile | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Pregnenolone Carbonitrile results in increased expression of NEU2 mRNA | CTD | PMID:19162173 | rac-lactic acid | decreases expression | EXP | | 6480464 | Lactic Acid results in decreased expression of NEU2 mRNA | CTD | PMID:30851411 | silver atom | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | Silver results in increased expression of NEU2 mRNA | CTD | PMID:27131904 | silver(0) | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | Silver results in increased expression of NEU2 mRNA | CTD | PMID:27131904 | streptozocin | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Streptozocin results in increased expression of NEU2 mRNA | CTD | PMID:25905778 | tamoxifen | decreases expression | ISO | Neu2 (Mus musculus) | 6480464 | Tamoxifen results in decreased expression of NEU2 mRNA | CTD | PMID:25123088 | tamoxifen | affects expression | ISO | Neu2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of NEU2 mRNA | CTD | PMID:20937368 | testosterone | multiple interactions | ISO | Neu2 (Rattus norvegicus) | 6480464 | Testosterone inhibits the reaction [Dexamethasone results in decreased expression of NEU2 mRNA] | CTD | PMID:20032058 | tetrachloromethane | decreases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Carbon Tetrachloride results in decreased expression of NEU2 mRNA | CTD | PMID:31150632 | tetrachloromethane | multiple interactions | ISO | Neu2 (Rattus norvegicus) | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in decreased expression of NEU2 mRNA] | CTD | PMID:31150632 | tetraphene | multiple interactions | ISO | Neu2 (Mus musculus) | 6480464 | [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of NEU2 mRNA | CTD | PMID:27858113 | thioacetamide | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Thioacetamide affects the expression of NEU2 mRNA | CTD | PMID:19483382 | thioacetamide | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Thioacetamide results in increased expression of NEU2 mRNA | CTD | PMID:23411599 | trichloroethene | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of NEU2 mRNA | CTD | PMID:33387578 | triphenyl phosphate | affects expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | triphenyl phosphate affects the expression of NEU2 mRNA | CTD | PMID:30589522 | triptonide | increases expression | ISO | Neu2 (Mus musculus) | 6480464 | triptonide results in increased expression of NEU2 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of NEU2 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | Neu2 (Rattus norvegicus) | 6480464 | Valproic Acid results in increased expression of NEU2 mRNA | CTD | PMID:23665938 | |