Gene: ADRA1A (adrenoceptor alpha 1A)  Homo sapiens

Symbol: ADRA1A
Name: adrenoceptor alpha 1A
Description: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ADRA1C; ADRA1L1; adrenergic receptor, alpha 1a; adrenergic, alpha -1A-, receptor; adrenergic, alpha-1A-, receptor variant 1; adrenergic, alpha-1A-, receptor variant 3; adrenergic, alpha-1A-, receptor variant 5; adrenergic, alpha-1A-, receptor variant 8; adrenergic, alpha-1C-, receptor; alpha-1A adrenergic receptor; alpha-1A adrenoceptor; alpha-1A adrenoreceptor; alpha-1C adrenergic receptor; alpha-adrenergic receptor 1c; ALPHA1AAR; G protein coupled receptor; OTTHUMP00000125310; OTTHUMP00000125311; OTTHUMP00000125312; OTTHUMP00000125313
Orthologs: Mus musculus : Adra1a (adrenergic receptor, alpha 1a)  MGI
Rattus norvegicus : Adra1a (adrenoceptor alpha 1A)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1826,842,338 - 26,959,595-NCBI
Human Genome Assembly HuRef825,150,527 - 25,267,740-NCBI
Human Genome Assembly GRCh37826,605,667 - 26,722,922-NCBI
Human Genome Assembly Build 36826,661,584 - 26,778,839-NCBI
Human Cytogenetic Map8p21.2 NCBI
Human Genome Assembly826,679,287 - 26,778,603 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on ADRA1A
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
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Vista
Vista + UCSC

RGD Object Information
RGD ID: 736081
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE