Gene: Scn1a (sodium channel, voltage-gated, type I, alpha) Mus musculus
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Symbol: Scn1a
Name: sodium channel, voltage-gated, type I, alpha
Description: ENCODES a protein that exhibits voltage-gated sodium channel activity; sodium ion binding (ortholog); INVOLVED IN action potential; adult walking behavior; detection of mechanical stimulus involved in sensory perception of pain; ASSOCIATED WITH abnormal action potential; abnormal brain wave pattern; abnormal cardiovascular system physiology; ASSOCIATED WITH Abnormalities, Multiple (ortholog); adolescence-adult electroclinical syndrome (ortholog); Autism Spectrum Disorder (ortholog); FOUND IN axon; axon initial segment; intercalated disc; INTERACTS WITH 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl; 3,4-methylenedioxymethamphetamine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: B230332M13; Nav1.1; OTTMUSP00000014085; OTTMUSP00000014086; OTTMUSP00000014087; sodium channel protein brain I subunit alpha; sodium channel protein type 1 subunit alpha; sodium channel protein type I subunit alpha; voltage-gated sodium channel subunit alpha Nav1.1
Orthologs:
Homo sapiens (human) : SCN1A (sodium voltage-gated channel alpha subunit 1)  HGNC
Rattus norvegicus (Norway rat) : Scn1a (sodium voltage-gated channel alpha subunit 1)
Chinchilla lanigera (long-tailed chinchilla) : Scn1a (sodium voltage-gated channel alpha subunit 1)
Pan paniscus (bonobo/pygmy chimpanzee) : SCN1A (sodium voltage-gated channel alpha subunit 1)
Canis lupus familiaris (dog) : SCN1A (sodium voltage-gated channel alpha subunit 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Scn1a (sodium voltage-gated channel alpha subunit 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38266,270,782 - 66,440,837 (-)NCBIGRCm38mm10GRCm38
MGSCv37266,108,839 - 66,278,894 (-)NCBIGRCm37mm9NCBIm37
MGSCv36266,071,621 - 66,241,676 (-)NCBImm8
Celera267,950,131 - 68,119,920 (-)NCBI
Cytogenetic Map2 C1.3NCBImapview
cM Map239.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Scn1a
NCBI Gene
Ensembl Gene
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MGI Report
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RGD Object Information
RGD ID: 735778
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2017-09-05
Status: ACTIVE