Gene: GRIK3 (glutamate receptor, ionotropic, kainate 3)  Homo sapiens

Symbol: GRIK3
Name: glutamate receptor, ionotropic, kainate 3
Description: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. It is not certain if the subunit encoded by this gene is subject to RNA editing as the other 2 family members (GRIK1 and GRIK2). A Ser310Ala polymorphism has been associated with schizophrenia, and there are conflicting reports of its association with the pathogenesis of delirium tremens in alcoholics. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dJ1090M5.1 (glutamate receptor, ionotropic, kainate 3 (GLUR7)); EAA5; excitatory amino acid receptor 5; GLR7; GluK3; gluR-7; GLUR7; GluR7a; glutamate receptor 7; glutamate receptor ionotropic, kainate 3; glutamate receptor, ionotropic kainate 3; OTTHUMP00000004360; OTTHUMP00000004361
Orthologs: Mus musculus : Grik3 (glutamate receptor, ionotropic, kainate 3)  MGI
Rattus norvegicus : Grik3 (glutamate receptor, ionotropic, kainate 3)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_1137,342,021 - 37,580,677-NCBI
Human Genome Assembly HuRef135,378,101 - 35,617,482-NCBI
Human Genome Assembly GRCh37137,261,128 - 37,499,844-NCBI
Human Genome Assembly Build 36137,039,201 - 37,272,431-NCBI
Human Cytogenetic Map1p34.3 NCBI
Human Genome Assembly136,935,706 - 37,168,937 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
 
More on GRIK3
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 735713
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE