Adh4 (alcohol dehydrogenase 4 (class II), pi polypeptide) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Adh4 (alcohol dehydrogenase 4 (class II), pi polypeptide) Mus musculus
Analyze
Symbol: Adh4
Name: alcohol dehydrogenase 4 (class II), pi polypeptide
RGD ID: 735490
MGI Page MGI
Description: Enables NADPH:quinone reductase activity; alcohol dehydrogenase activity, zinc-dependent; and alditol:NADP+ 1-oxidoreductase activity. Involved in fatty acid omega-oxidation. Acts upstream of or within several processes, including alcohol catabolic process; ethanol metabolic process; and quinone metabolic process. Predicted to be located in nucleoplasm. Predicted to be active in cytosol. Is expressed in several structures, including adrenal cortex; genitourinary system; integumental system; limb; and nervous system. Human ortholog(s) of this gene implicated in alcohol dependence. Orthologous to human ADH4 (alcohol dehydrogenase 4 (class II), pi polypeptide).
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Adh; Adh2; alcohol dehydrogenase 2; alcohol dehydrogenase 4; alcohol dehydrogenase class II; alcohol dehydrogenase II; all-trans-retinol dehydrogenase [NAD(+)] ADH4; class II type ADH
RGD Orthologs
Human
Rat
Bonobo
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393138,121,217 - 138,138,444 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3138,121,227 - 138,136,653 (+)EnsemblGRCm39 Ensembl
GRCm383138,415,456 - 138,432,683 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,415,466 - 138,430,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv373138,078,461 - 138,093,856 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,352,896 - 138,368,279 (+)NCBIMGSCv36mm8
Celera3144,836,181 - 144,853,583 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map364.24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(1->4)-beta-D-glucan  (EXP)
(2,4,5-trichlorophenoxy)acetic acid  (EXP)
17beta-estradiol  (ISO)
1H-pyrazole  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-palmitoylglycerol  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetaldehyde  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
aldrin  (EXP)
all-trans-retinal  (ISO)
all-trans-retinoic acid  (EXP)
amiodarone  (ISO)
ammonium chloride  (ISO)
atazanavir sulfate  (ISO)
benzbromarone  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (EXP)
bexarotene  (ISO)
bisphenol A  (ISO)
bosentan  (ISO)
buta-1,3-diene  (EXP)
cadmium dichloride  (ISO)
CGP 52608  (ISO)
chenodeoxycholic acid  (ISO)
chloroethene  (EXP)
cimetidine  (ISO)
clofibrate  (ISO)
copper(II) sulfate  (EXP,ISO)
cyclosporin A  (ISO)
cyhalothrin  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (ISO)
dibenzofurans  (EXP)
dicrotophos  (ISO)
endosulfan  (ISO)
epoxiconazole  (EXP)
ethanol  (EXP,ISO)
ethylene glycol  (ISO)
fenofibrate  (ISO)
fipronil  (ISO)
flutamide  (ISO)
fomepizole  (ISO)
formaldehyde  (ISO)
furan  (ISO)
gentamycin  (ISO)
glafenine  (ISO)
glycochenodeoxycholic acid  (ISO)
glycocholic acid  (ISO)
glycodeoxycholic acid  (ISO)
indometacin  (ISO)
L-ethionine  (ISO)
Lasiocarpine  (ISO)
lead(0)  (ISO)
metformin  (ISO)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
N-Nitrosopyrrolidine  (ISO)
nefazodone  (ISO)
niclosamide  (ISO)
O-methyleugenol  (ISO)
omeprazole  (ISO)
orphenadrine  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorononanoic acid  (ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenformin  (ISO)
phenobarbital  (EXP,ISO)
pirinixic acid  (EXP,ISO)
potassium dichromate  (EXP)
pregnenolone 16alpha-carbonitrile  (EXP)
prochloraz  (ISO)
procymidone  (ISO)
propan-2-ol  (ISO)
propiconazole  (EXP)
quercetin  (ISO)
quinolin-8-ol  (ISO)
rotenone  (ISO)
silicon dioxide  (EXP,ISO)
sodium arsenite  (ISO)
sodium dichromate  (ISO)
Sunset Yellow FCF  (ISO)
tartrazine  (ISO)
tebuconazole  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (ISO)
triadimefon  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (ISO)
troglitazone  (ISO)
urethane  (ISO)
valproic acid  (EXP,ISO)
zinc atom  (EXP)
zinc(0)  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IEA)
cytosol  (IBA,ISO)
nucleoplasm  (ISO)

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Gender differences in the genetic risk for alcohol dependence--the results of a pharmacogenetic study in Korean alcoholics. Kim SG, Nihon Arukoru Yakubutsu Igakkai Zasshi. 2009 Dec;44(6):680-5.
2. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
3. MGDs mouse GO annotations MGD data from the GO Consortium
4. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. A rodent model of low- to moderate-dose ethanol consumption during pregnancy: patterns of ethanol consumption and effects on fetal and offspring growth. Probyn ME, etal., Reprod Fertil Dev. 2012;24(6):859-70. doi: 10.1071/RD11200.
7. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
8. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
9. Ethanol concentration-dependent alterations in gene expression during acute binge drinking in the HIV-1 transgenic rat. Sarkar S and Chang SL, Alcohol Clin Exp Res. 2013 Jul;37(7):1082-90. doi: 10.1111/acer.12077. Epub 2013 Feb 15.
10. Molecular analysis of cluster headache. Zarrilli F, etal., Clin J Pain. 2015 Jan;31(1):52-7. doi: 10.1097/AJP.0000000000000075.
Additional References at PubMed
PMID:518534   PMID:10349636   PMID:10514444   PMID:10753524   PMID:10970744   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11747070   PMID:11784316   PMID:11836246   PMID:12027900  
PMID:12477932   PMID:12631290   PMID:14681479   PMID:14756569   PMID:16047160   PMID:16081420   PMID:16121213   PMID:16141072   PMID:16141073   PMID:17257171   PMID:17270348   PMID:17279314  
PMID:21075145   PMID:21106844   PMID:21267068   PMID:21677750   PMID:21873635   PMID:22079585   PMID:22496890  


Genomics

Comparative Map Data
Adh4
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393138,121,217 - 138,138,444 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3138,121,227 - 138,136,653 (+)EnsemblGRCm39 Ensembl
GRCm383138,415,456 - 138,432,683 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3138,415,466 - 138,430,892 (+)EnsemblGRCm38mm10GRCm38
MGSCv373138,078,461 - 138,093,856 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363138,352,896 - 138,368,279 (+)NCBIMGSCv36mm8
Celera3144,836,181 - 144,853,583 (+)NCBICelera
Cytogenetic Map3G3NCBI
cM Map364.24NCBI
ADH4
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38499,123,658 - 99,144,297 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl499,123,657 - 99,157,792 (-)EnsemblGRCh38hg38GRCh38
GRCh374100,044,809 - 100,065,448 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364100,263,855 - 100,284,472 (-)NCBINCBI36Build 36hg18NCBI36
Build 344100,401,812 - 100,423,028NCBI
Celera497,342,359 - 97,362,981 (-)NCBICelera
Cytogenetic Map4q23NCBI
HuRef495,782,906 - 95,803,527 (-)NCBIHuRef
CHM1_14100,021,522 - 100,042,141 (-)NCBICHM1_1
T2T-CHM13v2.04102,438,693 - 102,459,340 (-)NCBIT2T-CHM13v2.0
Adh4
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82229,622,092 - 229,640,120 (+)NCBIGRCr8
mRatBN7.22226,948,717 - 226,966,747 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2226,947,466 - 226,987,591 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2234,697,253 - 234,715,474 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02232,596,984 - 232,615,201 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02227,461,666 - 227,479,885 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02243,702,035 - 243,720,063 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2243,700,784 - 243,740,899 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02262,237,059 - 262,254,499 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42235,952,313 - 235,970,671 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12235,939,028 - 235,957,343 (+)NCBI
Celera2219,105,553 - 219,122,791 (+)NCBICelera
Cytogenetic Map2q44NCBI
ADH4
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2397,188,649 - 97,209,293 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1497,464,601 - 97,485,231 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0491,522,444 - 91,543,086 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.14102,186,670 - 102,206,923 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4102,183,956 - 102,206,923 (-)Ensemblpanpan1.1panPan2
ADH4
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13221,282,526 - 21,299,387 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3221,282,890 - 21,299,328 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3220,631,099 - 20,647,963 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03221,468,468 - 21,485,373 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3221,468,474 - 21,485,323 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13221,433,849 - 21,450,220 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03221,260,783 - 21,277,661 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03218,617,963 - 18,634,846 (+)NCBIUU_Cfam_GSD_1.0
ADH4
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8121,225,656 - 121,261,746 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18121,225,485 - 121,259,262 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X98,582,002 - 98,583,002 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28130,409,996 - 130,434,606 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADH4
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1747,226,787 - 47,248,518 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl747,226,191 - 47,248,234 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603725,658,415 - 25,678,570 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Adh4
685 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:333
Count of miRNA genes:279
Interacting mature miRNAs:294
Transcripts:ENSMUST00000013458, ENSMUST00000161312, ENSMUST00000162260
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107376936147304689Mouse
1300619Cdcs1_mcytokine deficiency colitis susceptibility 1 (mouse)Not determined3109834882143835005Mouse
1301381Bomb1_mbone marrow pre-B 1 (mouse)Not determined3111133243145133417Mouse
1301100Bdt2_mbone density traits 2 (mouse)Not determined3114736617148736784Mouse
10043919Afpq8_mabdominal fat percent QTL 8 (mouse)Not determined3119057332153057456Mouse
1558868Ses9_msalmonella enteritidis susceptibility 9 (mouse)Not determined3119057332153057456Mouse
4141935Tgq15_mtriglyceride QTL 15 (mouse)Not determined119318586153318586Mouse
4142449Tgq14_mtriglyceride QTL 14 (mouse)Not determined119318586153318586Mouse
1302151Lprm2_mlymphoproliferation modifier 2 (mouse)Not determined3119778857153779044Mouse
10412240Alpq6_malcohol preference QTL 6 (mouse)Not determined3120772078154772078Mouse
4142245Pstc1_mperiosteal circumference 1 (mouse)Not determined3126270248159745316Mouse
1301218Letohc1_mlow ethanol consumption 1 (mouse)Not determined3126352986159745316Mouse
1301347Fpli_mfasting plasma insulin (mouse)Not determined3126460514159745316Mouse
1301563Alcp3_malcohol preference locus 3 (mouse)Not determined3130736935159745316Mouse
11039523Tbbr1_mTrypanosoma brucei brucei response 1 (mouse)3130849375159745316Mouse
1300753Eae10_msusceptibility to experimental allergic encephalomyelitis 10 (mouse)Not determined3131736617148451178Mouse
10412120Ccs3_mcolon cancer susceptibility 3 (mouse)Not determined3131754536146017669Mouse
1301528Loco1_mlocomotor activity 1 (mouse)Not determined3133461893159745316Mouse

Markers in Region
Adh4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3H2UniSTS
cM Map371.2UniSTS
cM Map3 UniSTS
cM MapUN UniSTS
Adh4  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3H2UniSTS
Cytogenetic Map3G3UniSTS
cM MapUN UniSTS
cM Map3 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_011996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030252627 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC079845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ245750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK132994 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100736 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466532 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571071 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571073 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571074 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571075 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571077 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571078 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571080 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571082 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571089 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571090 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571092 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571093 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571099 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HM571100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000013458   ⟹   ENSMUSP00000013458
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3138,121,256 - 138,136,653 (+)Ensembl
GRCm38.p6 Ensembl3138,415,495 - 138,430,892 (+)Ensembl
RefSeq Acc Id: ENSMUST00000161312   ⟹   ENSMUSP00000124163
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3138,121,248 - 138,129,789 (+)Ensembl
GRCm38.p6 Ensembl3138,415,487 - 138,424,028 (+)Ensembl
RefSeq Acc Id: ENSMUST00000162260
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3138,121,227 - 138,124,539 (+)Ensembl
GRCm38.p6 Ensembl3138,415,466 - 138,418,778 (+)Ensembl
RefSeq Acc Id: NM_011996   ⟹   NP_036126
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393138,121,258 - 138,136,653 (+)NCBI
GRCm383138,415,497 - 138,430,892 (+)ENTREZGENE
MGSCv373138,078,461 - 138,093,856 (+)RGD
Celera3144,836,181 - 144,853,583 (+)RGD
cM Map3 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030252627   ⟹   XP_030108487
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393138,121,217 - 138,138,444 (+)NCBI
GRCm383138,415,456 - 138,432,683 (+)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_036126   ⟸   NM_011996
- UniProtKB: Q3V0P5 (UniProtKB/Swiss-Prot),   Q9QYY9 (UniProtKB/Swiss-Prot),   Q496S1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030108487   ⟸   XM_030252627
- Peptide Label: isoform X1
- UniProtKB: Q496S1 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000013458   ⟸   ENSMUST00000013458
RefSeq Acc Id: ENSMUSP00000124163   ⟸   ENSMUST00000161312
Protein Domains
Alcohol dehydrogenase-like C-terminal   Alcohol dehydrogenase-like N-terminal

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9QYY9-F1-model_v2 AlphaFold Q9QYY9 1-377 view protein structure

Promoters
RGD ID:6833352
Promoter ID:MM_KWN:36237
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Liver
Transcripts:OTTMUST00000075538,   OTTMUST00000075539,   OTTMUST00000075540
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363138,078,226 - 138,078,726 (+)MPROMDB
RGD ID:6882488
Promoter ID:EPDNEW_M4695
Type:initiation region
Name:Adh4_1
Description:Mus musculus alcohol dehydrogenase 4 , pi polypeptide , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383138,415,463 - 138,415,523EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1349472 AgrOrtholog
Ensembl Genes ENSMUSG00000037797 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000013458 ENTREZGENE
  ENSMUST00000013458.9 UniProtKB/Swiss-Prot
  ENSMUST00000161312.8 UniProtKB/TrEMBL
Gene3D-CATH Medium-chain alcohol dehydrogenases, catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADH_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_Zn_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GroES-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:26876 UniProtKB/Swiss-Prot
MGD MGI:1349472 ENTREZGENE
NCBI Gene 26876 ENTREZGENE
PANTHER ALCOHOL DEHYDROGENASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR43880:SF14 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ADH_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ADH_zinc_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB ADH4 RGD
PhenoGen Adh4 PhenoGen
PROSITE ADH_ZINC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50129 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt ADH4_MOUSE UniProtKB/Swiss-Prot
  E0CYI4_MOUSE UniProtKB/TrEMBL
  Q3V0P5 ENTREZGENE
  Q496S1 ENTREZGENE, UniProtKB/TrEMBL
  Q9QYY9 ENTREZGENE
UniProt Secondary Q3V0P5 UniProtKB/Swiss-Prot