Bmpr2 (bone morphogenetic protein receptor, type II (serine/threonine kinase))

Help | FTP Download | Citing RGD | Contact Us

Keyword

Gene: Bmpr2 (bone morphogenetic protein receptor, type II (serine/threonine kinase)) Mus musculus

Symbol:

Bmpr2

Name:

bone morphogenetic protein receptor, type II (serine/threonine kinase)

Description:

This gene encodes a serine/threonine kinase that functions as a receptor for bone morphogenetic proteins (BMPs). The encoded protein is a type II receptor that binds extracellular BMPs and forms a complex of two type II and two type I receptors at the cell membrane. This complex signals downstream to activate SMAD transcriptional regulators. This signaling is important during embryonic development. Mutations in this gene can cause pulmonary hypertension. [provided by RefSeq, Mar 2013]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

2610024H22Rik; AL117858; AW546137; BB189135; BMP type II receptor; BMP type-2 receptor; BMP-2; BMPR-2; BMPR-2; BMPR-II; BMPRII; bone morphogenetic protein receptor type II; bone morphogenetic protein receptor type-2; bone morphogenic protein receptor, type II (serine/threonine kinase); BRK-3; BRK-3; Gm20272

Orthologs:

Homo sapiens : BMPR2 (bone morphogenetic protein receptor, type II (serine/threonine kinase)) HGNC
Rattus norvegicus : Bmpr2 (bone morphogenetic protein receptor, type II (serine/threonine kinase))

Latest Assembly:

Mouse Genome Assembly Build 37

Position:

Map	Chr	Position	Strand	Source
Mouse Genome Assembly GRCm38	1	59,764,637 - 59,870,859	+	NCBI
Mouse cM Map	1		+	NCBI
Mouse Celera Assembly	1	60,279,442 - 60,385,822	+	NCBI
Mouse Genome Assembly Build 37	1	59,821,481 - 59,927,703	+	NCBI
Mouse Genome Assembly Build 36.1	1	59,821,481 - 59,927,703	+	NCBI
Mouse Cytogenetic Map	1	C1.3		NCBI