Mybpc1 (myosin binding protein C1) - Rat Genome Database

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Gene: Mybpc1 (myosin binding protein C1) Rattus norvegicus
Analyze
Symbol: Mybpc1
Name: myosin binding protein C1
RGD ID: 735102
Description: Predicted to enable myosin binding activity. Predicted to be involved in muscle contraction. Predicted to be located in intracellular non-membrane-bounded organelle and myosin filament. Human ortholog(s) of this gene implicated in congenital myopathy 16; distal arthrogryposis type 1B; and lethal congenital contracture syndrome 4. Orthologous to human MYBPC1 (myosin binding protein C1); INTERACTS WITH 1-[(4-chlorophenyl)-phenylmethyl]-4-methylpiperazine; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C-protein, skeletal muscle slow isoform; muscle C-protein; myosin binding protein C, slow type; myosin-binding protein C, slow-type; slow MyBP-C
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8724,817,770 - 24,903,681 (-)NCBIGRCr8
mRatBN7.2722,930,350 - 23,015,981 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl722,930,350 - 23,015,957 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx724,924,950 - 25,010,540 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0727,087,634 - 27,173,231 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0726,864,689 - 26,950,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0729,086,159 - 29,171,909 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl729,086,156 - 29,171,783 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0729,192,153 - 29,277,697 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4725,213,498 - 25,300,435 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1725,233,771 - 25,269,625 (-)NCBI
Celera720,090,183 - 20,175,952 (-)NCBICelera
Cytogenetic Map7q13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function
actin binding  (IEA)
myosin binding  (IEA,ISO,ISS,TAS)
protein binding  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Peripheral nervous system-specific genes identified by subtractive cDNA cloning. Akopian AN and Wood JN, J Biol Chem 1995 Sep 8;270(36):21264-70.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Myosin-binding protein C (MyBP-C) in cardiac muscle and contractility. Winegrad S Adv Exp Med Biol 2003;538:31-40; discussion 40-1.
Additional References at PubMed
PMID:8618961   PMID:17900708   PMID:18817784   PMID:19403693   PMID:22206666   PMID:24270810  


Genomics

Comparative Map Data
Mybpc1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8724,817,770 - 24,903,681 (-)NCBIGRCr8
mRatBN7.2722,930,350 - 23,015,981 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl722,930,350 - 23,015,957 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx724,924,950 - 25,010,540 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0727,087,634 - 27,173,231 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0726,864,689 - 26,950,284 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0729,086,159 - 29,171,909 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl729,086,156 - 29,171,783 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0729,192,153 - 29,277,697 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4725,213,498 - 25,300,435 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1725,233,771 - 25,269,625 (-)NCBI
Celera720,090,183 - 20,175,952 (-)NCBICelera
Cytogenetic Map7q13NCBI
MYBPC1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3812101,594,971 - 101,695,841 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl12101,568,353 - 101,686,028 (+)EnsemblGRCh38hg38GRCh38
GRCh3712101,988,749 - 102,079,806 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612100,512,878 - 100,603,789 (+)NCBINCBI36Build 36hg18NCBI36
Build 3412100,491,214 - 100,582,126NCBI
Celera12101,653,418 - 101,744,340 (+)NCBICelera
Cytogenetic Map12q23.2NCBI
HuRef1299,048,762 - 99,139,697 (+)NCBIHuRef
CHM1_112101,955,428 - 102,046,334 (+)NCBICHM1_1
T2T-CHM13v2.012101,556,082 - 101,657,067 (+)NCBIT2T-CHM13v2.0
Mybpc1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391088,354,141 - 88,441,051 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1088,354,141 - 88,441,014 (-)EnsemblGRCm39 Ensembl
GRCm381088,518,279 - 88,605,229 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1088,518,279 - 88,605,152 (-)EnsemblGRCm38mm10GRCm38
MGSCv371087,981,027 - 88,067,897 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361087,948,081 - 88,034,813 (-)NCBIMGSCv36mm8
Celera1090,498,217 - 90,585,463 (-)NCBICelera
Cytogenetic Map10C1NCBI
cM Map1043.99NCBI
Mybpc1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540536,992,564 - 37,070,380 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540536,992,798 - 37,066,154 (+)NCBIChiLan1.0ChiLan1.0
MYBPC1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v210109,664,819 - 109,754,236 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan112109,678,688 - 109,750,828 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01299,179,611 - 99,269,521 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.112102,578,014 - 102,669,618 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl12102,578,014 - 102,669,618 (+)Ensemblpanpan1.1panPan2
MYBPC1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11540,504,974 - 40,590,441 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1540,504,160 - 40,613,978 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1540,873,662 - 40,958,786 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01541,160,019 - 41,244,473 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1541,160,056 - 41,244,474 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11540,414,805 - 40,498,417 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01540,523,727 - 40,607,814 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01540,797,933 - 40,882,213 (+)NCBIUU_Cfam_GSD_1.0
Mybpc1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494519,362,845 - 19,444,730 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493649212,374,708 - 12,455,031 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493649212,373,240 - 12,455,371 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MYBPC1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl582,557,609 - 82,696,126 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1582,557,975 - 82,651,237 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2586,510,703 - 86,642,297 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MYBPC1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11196,843,331 - 96,942,336 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1196,843,512 - 96,944,035 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666037148,061,325 - 148,160,459 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mybpc1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247506,382,065 - 6,447,317 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247506,380,658 - 6,447,404 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mybpc1
500 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:40
Count of miRNA genes:36
Interacting mature miRNAs:40
Transcripts:ENSRNOT00000037877
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2298550Neuinf6Neuroinflammation QTL 63.3nervous system integrity trait (VT:0010566)spinal cord RT1-B protein level (CMO:0002132)7127829089Rat
7411566Bw136Body weight QTL 13610.40.001body mass (VT:0001259)body weight gain (CMO:0000420)7131962314Rat
9590142Scort5Serum corticosterone level QTL 524.40.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)7131962314Rat
724560Plsm3Polydactyly-luxate syndrome (PLS) morphotypes QTL 30.0003tibia length (VT:0004357)tibia length (CMO:0000450)7134000259Rat
2317047Wbc4White blood cell count QTL 40.01leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)7135342956Rat
61410Bw19Body weight QTL 196.20.001body mass (VT:0001259)body weight (CMO:0000012)7144782185Rat
631503Bp102Blood pressure QTL 1021.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)7144822433Rat
1300176Hrtrt10Heart rate QTL 103.19heart pumping trait (VT:2000009)heart rate (CMO:0000002)766427026029351Rat
634336Anxrr17Anxiety related response QTL 173.66locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)7924703115097879Rat
10755438Coatc9Coat color QTL 90coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7352928048529280Rat
9590102Sffal5Serum free fatty acids level QTL 58.620.001blood free fatty acid amount (VT:0001553)plasma free fatty acids level (CMO:0000546)7532901950329019Rat
10755440Coatc10Coat color QTL 100coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)7749649952496499Rat
10059592Kidm45Kidney mass QTL 453.950.025kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)7757398552573985Rat
2298547Neuinf5Neuroinflammation QTL 53.7nervous system integrity trait (VT:0010566)spinal cord Cd74 protein level (CMO:0002131)7946224658265113Rat
1643004Pain2Pain QTL 21mechanical nociception trait (VT:0002734)self mutilation severity score (CMO:0002145)7946224698011544Rat
1578652Bmd15Bone mineral density QTL 155.2femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)7986646760460686Rat
738033Anxrr6Anxiety related response QTL 64.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)71557388960573889Rat
1582260Bw72Body weight QTL 723.20.0043body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582261Bw69Body weight QTL 693.20.0048body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
1582262Bw75Body weight QTL 7530.0038body mass (VT:0001259)body weight (CMO:0000012)71579556538073970Rat
2317059Aia15Adjuvant induced arthritis QTL 152.46joint integrity trait (VT:0010548)right rear ankle joint diameter (CMO:0002150)71700459862004598Rat
10755451Coatc11Coat color QTL 110coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)71794435762944357Rat
70207Niddm31Non-insulin dependent diabetes mellitus QTL 313.9blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)71816950526029351Rat
61369Mcs2Mammary carcinoma susceptibility QTL 23.38mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)71903280735526300Rat
1354637Scl30Serum cholesterol level QTL 303.7blood cholesterol amount (VT:0000180)blood total cholesterol level (CMO:0000051)71965431749753746Rat
1354644Spl4Serum phospholipid level QTL 44.9blood phospholipid amount (VT:0006084)blood phospholipid level (CMO:0001169)71965431749753746Rat
1354639Spl5Serum phospholipid level QTL 53.9blood LDL phospholipid amount (VT:0010505)blood low density lipoprotein phospholipid level (CMO:0001568)71965431752888450Rat
1300132Bp182Blood pressure QTL 1823.49arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)71965431784928080Rat
2290372Gluco33Glucose level QTL 332.71blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)72055570529891047Rat
7411569Bw137Body weight QTL 1370.001body mass (VT:0001259)body weight gain (CMO:0000420)72192119566921195Rat


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 6 8 6
Medium 10 2 2 2 3 7 12 7 2
Low 2 36 24 16 19 16 49 27 27 2
Below cutoff 1 7 19 19 19 18 8 2 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100758 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765246 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765247 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765257 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008765258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263764 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063263768 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC121402 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ214958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000007 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X90475 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000079235   ⟹   ENSRNOP00000074295
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,930,350 - 23,015,957 (-)Ensembl
Rnor_6.0 Ensembl729,086,156 - 29,171,783 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000079774   ⟹   ENSRNOP00000069067
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,933,133 - 22,984,151 (-)Ensembl
Rnor_6.0 Ensembl729,091,341 - 29,152,442 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093952   ⟹   ENSRNOP00000088357
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,935,448 - 23,015,957 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000096740   ⟹   ENSRNOP00000089644
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,930,351 - 23,015,957 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000099906   ⟹   ENSRNOP00000081596
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,930,361 - 23,015,957 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000108545   ⟹   ENSRNOP00000081963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,930,350 - 23,015,957 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000113153   ⟹   ENSRNOP00000083276
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,930,350 - 23,015,957 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000116177   ⟹   ENSRNOP00000096490
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl722,930,350 - 23,015,957 (-)Ensembl
RefSeq Acc Id: NM_001100758   ⟹   NP_001094228
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,373 (-)NCBI
mRatBN7.2722,930,350 - 23,015,957 (-)NCBI
Rnor_6.0729,086,159 - 29,171,787 (-)NCBI
Rnor_5.0729,192,153 - 29,277,697 (-)NCBI
Celera720,090,183 - 20,175,952 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765246   ⟹   XP_008763468
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,159 - 29,171,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765247   ⟹   XP_008763469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,982 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,159 - 29,171,909 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765249   ⟹   XP_008763471
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,159 - 29,171,908 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765250   ⟹   XP_008763472
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,159 - 29,171,905 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765251   ⟹   XP_008763473
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,159 - 29,171,907 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765253   ⟹   XP_008763475
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,982 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,163 - 29,171,905 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765255   ⟹   XP_008763477
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,982 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,163 - 29,171,907 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765256   ⟹   XP_008763478
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,159 - 29,171,906 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765257   ⟹   XP_008763479
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,981 (-)NCBI
Rnor_6.0729,086,159 - 29,171,903 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008765258   ⟹   XP_008763480
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,982 - 24,903,681 (-)NCBI
mRatBN7.2722,930,350 - 23,015,980 (-)NCBI
Rnor_6.0729,086,163 - 29,171,903 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063263763   ⟹   XP_063119833
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
RefSeq Acc Id: XM_063263764   ⟹   XP_063119834
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
RefSeq Acc Id: XM_063263765   ⟹   XP_063119835
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
RefSeq Acc Id: XM_063263766   ⟹   XP_063119836
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
RefSeq Acc Id: XM_063263767   ⟹   XP_063119837
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
RefSeq Acc Id: XM_063263768   ⟹   XP_063119838
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8724,817,770 - 24,903,681 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001094228 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763468 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763469 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763471 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763472 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763473 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763475 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763477 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763478 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763479 (Get FASTA)   NCBI Sequence Viewer  
  XP_008763480 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119833 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119834 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119835 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119836 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119837 (Get FASTA)   NCBI Sequence Viewer  
  XP_063119838 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein CAA62085 (Get FASTA)   NCBI Sequence Viewer  
  EDM17000 (Get FASTA)   NCBI Sequence Viewer  
  EDM17001 (Get FASTA)   NCBI Sequence Viewer  
  EDM17002 (Get FASTA)   NCBI Sequence Viewer  
  EDM17003 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000069067
  ENSRNOP00000069067.2
  ENSRNOP00000074295
  ENSRNOP00000074295.2
  ENSRNOP00000081596
  ENSRNOP00000081596.1
  ENSRNOP00000081963.1
  ENSRNOP00000083276.1
  ENSRNOP00000088357
  ENSRNOP00000088357.1
  ENSRNOP00000089644
  ENSRNOP00000089644.1
  ENSRNOP00000096490.1
GenBank Protein Q63518 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_001094228   ⟸   NM_001100758
- UniProtKB: A0A0G2K7Q0 (UniProtKB/TrEMBL),   A0A8I5ZT65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763468   ⟸   XM_008765246
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZT65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763469   ⟸   XM_008765247
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZT65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763471   ⟸   XM_008765249
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZWN5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763473   ⟸   XM_008765251
- Peptide Label: isoform X6
- UniProtKB: A0A8I6ATF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763477   ⟸   XM_008765255
- Peptide Label: isoform X11
- UniProtKB: A0A8I6AAS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763478   ⟸   XM_008765256
- Peptide Label: isoform X12
- UniProtKB: A0A8I6ATF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763472   ⟸   XM_008765250
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZT65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763475   ⟸   XM_008765253
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZT65 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763479   ⟸   XM_008765257
- Peptide Label: isoform X13
- UniProtKB: A0A8I6ATF3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008763480   ⟸   XM_008765258
- Peptide Label: isoform X15
- UniProtKB: A0A8I6AAS2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000074295   ⟸   ENSRNOT00000079235
RefSeq Acc Id: ENSRNOP00000069067   ⟸   ENSRNOT00000079774
RefSeq Acc Id: ENSRNOP00000081596   ⟸   ENSRNOT00000099906
RefSeq Acc Id: ENSRNOP00000089644   ⟸   ENSRNOT00000096740
RefSeq Acc Id: ENSRNOP00000081963   ⟸   ENSRNOT00000108545
RefSeq Acc Id: ENSRNOP00000096490   ⟸   ENSRNOT00000116177
RefSeq Acc Id: ENSRNOP00000083276   ⟸   ENSRNOT00000113153
RefSeq Acc Id: ENSRNOP00000088357   ⟸   ENSRNOT00000093952
RefSeq Acc Id: XP_063119838   ⟸   XM_063263768
- Peptide Label: isoform X16
- UniProtKB: A0A8I5ZTA0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063119837   ⟸   XM_063263767
- Peptide Label: isoform X14
RefSeq Acc Id: XP_063119834   ⟸   XM_063263764
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063119836   ⟸   XM_063263766
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063119835   ⟸   XM_063263765
- Peptide Label: isoform X9
RefSeq Acc Id: XP_063119833   ⟸   XM_063263763
- Peptide Label: isoform X2
Protein Domains
Fibronectin type-III   Ig-like   Ig-like C2-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q63518-F1-model_v2 AlphaFold Q63518 1-621 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695129
Promoter ID:EPDNEW_R5654
Type:single initiation site
Name:Mybpc1_1
Description:myosin binding protein C, slow type
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0729,171,785 - 29,171,845EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735102 AgrOrtholog
BioCyc Gene G2FUF-34505 BioCyc
Ensembl Genes ENSRNOG00000056493 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000079235 ENTREZGENE
  ENSRNOT00000079235.2 UniProtKB/TrEMBL
  ENSRNOT00000079774.2 UniProtKB/TrEMBL
  ENSRNOT00000093952.1 UniProtKB/TrEMBL
  ENSRNOT00000096740.1 UniProtKB/TrEMBL
  ENSRNOT00000099906.1 UniProtKB/TrEMBL
  ENSRNOT00000108545.1 UniProtKB/TrEMBL
  ENSRNOT00000113153.1 UniProtKB/TrEMBL
  ENSRNOT00000116177.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro FN3_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  FN3_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ig_sub2 UniProtKB/TrEMBL
  MyBP-C_THB UniProtKB/TrEMBL
KEGG Report rno:362867 UniProtKB/Swiss-Prot
NCBI Gene 362867 ENTREZGENE
PANTHER MYOSIN-BINDING PROTEIN C, SLOW-TYPE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TITIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam fn3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  I-set UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  THB UniProtKB/TrEMBL
PhenoGen Mybpc1 PhenoGen
PRINTS FNTYPEIII UniProtKB/TrEMBL
PROSITE FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IG_LIKE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000056493 RatGTEx
SMART FN3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IGc2 UniProtKB/TrEMBL
  SM00409 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF48726 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF49265 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0G2JUE5_RAT UniProtKB/TrEMBL
  A0A0G2K7Q0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZT65 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZTA0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZWN5 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AAS2 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6ATF3 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GG51_RAT UniProtKB/TrEMBL
  A6IFP5_RAT UniProtKB/TrEMBL
  A6IFP8_RAT UniProtKB/TrEMBL
  MYPC1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-11-11 Mybpc1  myosin binding protein C1  Mybpc1  myosin binding protein C, slow type  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-07-08 Mybpc1  myosin binding protein C, slow type      Symbol and Name status set to approved 1299863 APPROVED