Wdr12 (WD repeat domain 12) - Rat Genome Database

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Gene: Wdr12 (WD repeat domain 12) Rattus norvegicus
Analyze
Symbol: Wdr12
Name: WD repeat domain 12
RGD ID: 735072
Description: Predicted to enable ribonucleoprotein complex binding activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); and regulation of cell cycle. Predicted to act upstream of or within Notch signaling pathway. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of PeBoW complex and preribosome, large subunit precursor. Orthologous to human WDR12 (WD repeat domain 12); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: ribosome biogenesis protein WDR12; WD repeat-containing protein 12
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,969,547 - 68,996,811 (-)NCBIGRCr8
mRatBN7.2961,475,498 - 61,502,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,475,517 - 61,502,469 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,976,060 - 70,003,966 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,091,621 - 75,119,527 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,410,328 - 73,438,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,851,499 - 66,878,534 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,851,940 - 66,877,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,665,603 - 66,691,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,614,192 - 58,641,597 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,761,173 - 58,788,579 (-)NCBI
Celera958,910,009 - 58,934,061 (-)NCBICelera
Cytogenetic Map9q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
(-)-alpha-phellandrene  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-methylcholine  (ISO)
4-amino-2,6-dinitrotoluene  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-phellandrene  (ISO)
arsenous acid  (ISO)
Benoxacor  (ISO)
benzatropine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
carbon nanotube  (ISO)
CGP 52608  (ISO)
chromium(6+)  (ISO)
clofibric acid  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
decabromodiphenyl ether  (EXP)
diarsenic trioxide  (ISO)
dibutyl phthalate  (ISO)
dicrotophos  (ISO)
diethylstilbestrol  (ISO)
dioxygen  (ISO)
endosulfan  (EXP)
enzalutamide  (ISO)
ethyl methanesulfonate  (ISO)
fenvalerate  (EXP)
flutamide  (EXP)
FR900359  (ISO)
gentamycin  (EXP)
haloperidol  (ISO)
hydrogen peroxide  (ISO)
ivermectin  (ISO)
mercury atom  (EXP)
mercury(0)  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
paracetamol  (EXP,ISO)
paraquat  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
phenobarbital  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
quercetin  (ISO)
SB 431542  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium dichromate  (EXP)
succimer  (ISO)
sunitinib  (ISO)
tamoxifen  (ISO)
testosterone  (ISO)
tetrachloromethane  (EXP,ISO)
thioacetamide  (EXP)
trichloroethene  (EXP)
trimellitic anhydride  (ISO)
tungsten  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleolus  (ISO,ISS)
nucleoplasm  (IEA,ISO,ISS)
nucleus  (ISO)
PeBoW complex  (IBA,IEA,ISO,ISS)
preribosome, large subunit precursor  (IBA,IEA,ISO,ISS)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. Wdr12, a mouse gene encoding a novel WD-Repeat Protein with a notchless-like amino-terminal domain. Nal B, etal., Genomics 2002 Jan;79(1):77-86.
4. GOA pipeline RGD automated data pipeline
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:15489334   PMID:16043514   PMID:16738141   PMID:17353269   PMID:25915632  


Genomics

Comparative Map Data
Wdr12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8968,969,547 - 68,996,811 (-)NCBIGRCr8
mRatBN7.2961,475,498 - 61,502,762 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl961,475,517 - 61,502,469 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx969,976,060 - 70,003,966 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0975,091,621 - 75,119,527 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0973,410,328 - 73,438,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0966,851,499 - 66,878,534 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl966,851,940 - 66,877,972 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0966,665,603 - 66,691,634 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4958,614,192 - 58,641,597 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1958,761,173 - 58,788,579 (-)NCBI
Celera958,910,009 - 58,934,061 (-)NCBICelera
Cytogenetic Map9q32NCBI
WDR12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382202,874,261 - 202,911,673 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2202,874,261 - 203,014,798 (-)EnsemblGRCh38hg38GRCh38
GRCh372203,738,984 - 203,776,396 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362203,453,575 - 203,484,639 (-)NCBINCBI36Build 36hg18NCBI36
Build 342203,570,835 - 203,601,900NCBI
Celera2197,498,009 - 197,529,627 (-)NCBICelera
Cytogenetic Map2q33.2NCBI
HuRef2195,592,185 - 195,623,787 (-)NCBIHuRef
CHM1_12203,751,915 - 203,783,565 (-)NCBICHM1_1
T2T-CHM13v2.02203,355,718 - 203,393,126 (-)NCBIT2T-CHM13v2.0
Wdr12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39160,110,520 - 60,137,659 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl160,108,944 - 60,137,804 (-)EnsemblGRCm39 Ensembl
GRCm38160,071,361 - 60,098,500 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl160,069,785 - 60,098,645 (-)EnsemblGRCm38mm10GRCm38
MGSCv37160,133,712 - 60,154,722 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36160,021,414 - 60,042,424 (-)NCBIMGSCv36mm8
Celera160,592,628 - 60,613,639 (-)NCBICelera
Cytogenetic Map1C2NCBI
cM Map130.45NCBI
Wdr12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495545711,947,915 - 11,971,805 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495545711,947,816 - 11,970,066 (+)NCBIChiLan1.0ChiLan1.0
WDR12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v213105,483,663 - 105,514,951 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12B105,496,501 - 105,530,558 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02B90,112,037 - 90,145,520 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12B208,260,696 - 208,292,604 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2B208,260,696 - 208,291,783 (-)Ensemblpanpan1.1panPan2
WDR12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13711,762,598 - 11,787,025 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3711,762,777 - 11,786,933 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3712,646,140 - 12,670,826 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03711,699,520 - 11,724,283 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3711,695,221 - 11,723,916 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13711,655,780 - 11,680,470 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03711,627,136 - 11,651,850 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03711,621,045 - 11,645,767 (-)NCBIUU_Cfam_GSD_1.0
Wdr12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405303159,960,936 - 159,988,288 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367261,931,183 - 1,958,215 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367261,931,221 - 1,958,457 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
WDR12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl15106,380,755 - 106,410,416 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.115106,380,748 - 106,410,723 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.215117,834,705 - 117,860,610 (-)NCBISscrofa10.2Sscrofa10.2susScr3
WDR12
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11088,616,540 - 88,649,743 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1088,616,797 - 88,649,418 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666040110,738,393 - 110,768,906 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Wdr12
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476513,504,533 - 13,531,200 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476513,504,347 - 13,532,418 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Wdr12
96 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:85
Count of miRNA genes:69
Interacting mature miRNAs:75
Transcripts:ENSRNOT00000023463
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10054125Srcrt7Stress Responsive Cort QTL 73.330.0011blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)9187073594Rat
1331757Cdexp1CD45RC expression in CD8 T cells QTL 14.3CD8-positive T cell quantity (VT:0008077)blood CD45RC(high) CD8 T cell count to CD45RC(low) CD8 T cell count ratio (CMO:0001990)9102453767509080Rat
631680Cm11Cardiac mass QTL 113.10.00089heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)92043051965430519Rat
70186Niddm26Non-insulin dependent diabetes mellitus QTL 263.87blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)92207116986369743Rat
631643Bp120Blood pressure QTL 12030.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)92207120067071200Rat
7207814Bmd91Bone mineral density QTL 913.5femur size trait (VT:1000369)femoral neck cross-sectional area (CMO:0001697)92375414483851531Rat
70218Cm28Cardiac mass QTL 288.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)92526804479271759Rat
724544Uae9Urinary albumin excretion QTL 94.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)925268044114175309Rat
731164Uae25Urinary albumin excretion QTL 253.50.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)925661188100929786Rat
1641894Alcrsp12Alcohol response QTL 12response to alcohol trait (VT:0010489)brain neurotensin receptor 1 density (CMO:0002068)92746863972468639Rat
7411656Foco26Food consumption QTL 269.80.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)93253550577535505Rat
7411571Bw138Body weight QTL 13814.30.001body mass (VT:0001259)body weight gain (CMO:0000420)93253550577535505Rat
1598834Memor11Memory QTL 112.5exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)93696235977814038Rat
8662828Vetf6Vascular elastic tissue fragility QTL 63.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)93696235992058970Rat
2290450Scl57Serum cholesterol level QTL 574.15blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)93696235995410867Rat
6903941Pur31Proteinuria QTL 310.036urine total protein amount (VT:0000032)urine protein excretion rate (CMO:0000759)94019418885194188Rat
11353949Bp393Blood pressure QTL 393arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94019418885194188Rat
61352Bp34Blood pressure QTL 345arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94249534379271511Rat
10058949Gmadr5Adrenal mass QTL 520.014adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)94279151387976209Rat
11353951Bp394Blood pressure QTL 394arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94464992189649921Rat
12879506Pur33Proteinuria QTL 33urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)94464992189649921Rat
11353957Bmd92Bone mineral density QTL 920.01tibia mineral mass (VT:1000283)volumetric bone mineral density (CMO:0001553)94611419991114199Rat
631656Bp108Blood pressure QTL 1085.970.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)94859825193598251Rat
1598849Memor17Memory QTL 172.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)94996854671098346Rat
2303170Bp332Blood pressure QTL 3323.730.027arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95584784177026453Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)95662771378595166Rat
2303180Bp333Blood pressure QTL 3330.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)95662771378595166Rat
1578760Cm53Cardiac mass QTL 533.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)956771635101771635Rat
724515Uae16Urinary albumin excretion QTL 168urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)958163035100929646Rat
1578659Tspe1Trichinella spiralis expulsion QTL 14.8parasite quantity (VT:0010441)logarithm of the intestinal adult Trichinella spiralis count (CMO:0002024)96138143465691299Rat
1300134Bp185Blood pressure QTL 1853.73arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)961381434104821652Rat

Markers in Region
RH143036  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,479,822 - 61,480,001 (+)MAPPERmRatBN7.2
Rnor_6.0966,855,824 - 66,856,002NCBIRnor6.0
Rnor_5.0966,669,488 - 66,669,666UniSTSRnor5.0
RGSC_v3.4958,618,077 - 58,618,255UniSTSRGSC3.4
Celera958,913,894 - 58,914,072UniSTS
RH 3.4 Map9505.6UniSTS
Cytogenetic Map9q31UniSTS
RH132498  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,475,593 - 61,475,812 (+)MAPPERmRatBN7.2
Rnor_6.0966,851,595 - 66,851,813NCBIRnor6.0
Rnor_5.0966,665,259 - 66,665,477UniSTSRnor5.0
RGSC_v3.4958,613,848 - 58,614,066UniSTSRGSC3.4
Celera958,909,665 - 58,909,883UniSTS
RH 3.4 Map9514.4UniSTS
Cytogenetic Map9q31UniSTS
RH141263  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2953,338,478 - 53,338,658 (+)MAPPERmRatBN7.2
Rnor_6.0958,313,494 - 58,313,673NCBIRnor6.0
Rnor_5.0958,006,174 - 58,006,353UniSTSRnor5.0
RGSC_v3.4950,596,965 - 50,597,144UniSTSRGSC3.4
Celera950,906,476 - 50,906,655UniSTS
Cytogenetic Map9q22UniSTS
Cytogenetic Map9q31UniSTS
UniSTS:237290  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2961,480,874 - 61,481,369 (+)MAPPERmRatBN7.2
mRatBN7.2953,338,691 - 53,338,954 (+)MAPPERmRatBN7.2
Rnor_6.0966,856,876 - 66,857,370NCBIRnor6.0
Rnor_6.0958,313,707 - 58,313,969NCBIRnor6.0
Rnor_5.0966,670,540 - 66,671,034UniSTSRnor5.0
RGSC_v3.4950,597,178 - 50,597,547UniSTSRGSC3.4
RGSC_v3.4958,619,129 - 58,619,623UniSTSRGSC3.4
Celera958,914,946 - 58,915,440UniSTS
Cytogenetic Map9q22UniSTS
Cytogenetic Map9q31UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 3 35 57 41 19 41 8 11 74 35 41 11 8
Low 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000023463   ⟹   ENSRNOP00000023463
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,475,517 - 61,502,469 (-)Ensembl
Rnor_6.0 Ensembl966,851,940 - 66,877,972 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000111689   ⟹   ENSRNOP00000078380
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl961,475,517 - 61,499,636 (-)Ensembl
RefSeq Acc Id: NM_001393868   ⟹   NP_001380797
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,547 - 68,996,811 (-)NCBI
mRatBN7.2961,475,498 - 61,502,762 (-)NCBI
RefSeq Acc Id: NM_001393869   ⟹   NP_001380798
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,547 - 68,996,811 (-)NCBI
mRatBN7.2961,475,498 - 61,502,762 (-)NCBI
RefSeq Acc Id: NM_199410   ⟹   NP_955442
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,547 - 68,996,811 (-)NCBI
mRatBN7.2961,475,498 - 61,502,762 (-)NCBI
Rnor_6.0966,851,939 - 66,877,970 (-)NCBI
Rnor_5.0966,665,603 - 66,691,634 (-)NCBI
RGSC_v3.4958,614,192 - 58,641,597 (-)RGD
Celera958,910,009 - 58,934,061 (-)RGD
Sequence:
RefSeq Acc Id: XM_017596520   ⟹   XP_017452009
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8968,969,987 - 68,996,469 (-)NCBI
mRatBN7.2961,475,498 - 61,502,425 (-)NCBI
Rnor_6.0966,851,499 - 66,878,441 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_955442   ⟸   NM_199410
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017452009   ⟸   XM_017596520
- Peptide Label: isoform X1
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000023463   ⟸   ENSRNOT00000023463
RefSeq Acc Id: ENSRNOP00000078380   ⟸   ENSRNOT00000111689
RefSeq Acc Id: NP_001380798   ⟸   NM_001393869
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001380797   ⟸   NM_001393868
- UniProtKB: P61480 (UniProtKB/Swiss-Prot),   A6IPC1 (UniProtKB/TrEMBL),   A0A8I5ZKS8 (UniProtKB/TrEMBL)
Protein Domains
NLE

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P61480-F1-model_v2 AlphaFold P61480 1-423 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696705
Promoter ID:EPDNEW_R7230
Type:single initiation site
Name:Wdr12_1
Description:WD repeat domain 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0966,877,992 - 66,878,052EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735072 AgrOrtholog
BioCyc Gene G2FUF-27385 BioCyc
Ensembl Genes ENSRNOG00000017340 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00055024181 UniProtKB/Swiss-Prot
  ENSRNOG00060020402 UniProtKB/Swiss-Prot
  ENSRNOG00065029026 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000023463 ENTREZGENE
  ENSRNOT00000023463.6 UniProtKB/Swiss-Prot
  ENSRNOT00000111689.1 UniProtKB/TrEMBL
  ENSRNOT00055041606 UniProtKB/Swiss-Prot
  ENSRNOT00060035551 UniProtKB/Swiss-Prot
  ENSRNOT00065050214 UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6920424 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NLE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WDR12/Ytm1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:363237 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:72960 IMAGE-MGC_LOAD
NCBI Gene 363237 ENTREZGENE
PANTHER RIBOSOME BIOGENESIS PROTEIN WDR12 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 REPEAT PROTEIN 12, 37 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam NLE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Wdr12 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE WD_REPEATS_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017340 RatGTEx
  ENSRNOG00055024181 RatGTEx
  ENSRNOG00060020402 RatGTEx
  ENSRNOG00065029026 RatGTEx
SMART WD40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZKS8 ENTREZGENE, UniProtKB/TrEMBL
  A6IPC1 ENTREZGENE, UniProtKB/TrEMBL
  P61480 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2004-09-10 Wdr12  WD repeat domain 12      Symbol and Name status set to approved 1299863 APPROVED