Gene: Pde8b (phosphodiesterase 8B)  Rattus norvegicus

Symbol: Pde8b
Name: phosphodiesterase 8B
Description: ENCODES a protein that exhibits 3',5'-cyclic-nucleotide phosphodiesterase activity (inferred); metal ion binding (inferred); phosphorelay response regulator activity (inferred); INVOLVED IN negative regulation of insulin secretion; PARTICIPATES IN protein kinase A (PKA) signaling pathway; purine metabolic pathway; ASSOCIATED WITH Adrenal Hyperplasia, Congenital (ortholog); Striatal Degeneration, Autosomal Dominant (ortholog); INTERACTS WITH fluoxetine; lithium atom; olanzapine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: cAMP-specific cyclic nucleotide phosphodiesterase PDE8; high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B; phosphodiesterase 8B; RNPDE8B
Orthologs: Homo sapiens : PDE8B (phosphodiesterase 8B)  HGNC
Mus musculus : Pde8b (phosphodiesterase 8B)  MGI
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map2q12 NCBI
RGSC Genome Assembly v5.0243,879,335 - 43,984,030-NCBI
RGSC Genome Assembly v3.4225,352,725 - 25,469,209-NCBI
Rat Celera Assembly222,346,017 - 22,449,253-NCBI
Genome Assembly 3.1225,273,093 - 25,389,578-NCBI
Model

Launch Genome Browser (GBrowse)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pde8b
Entrez Gene
Ensembl Gene
Genome Browser
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 735041
Created: 2004-02-05
Species: Rattus norvegicus
Last Modified: 2013-05-28
Status: ACTIVE