CDH13 (cadherin 13, H-cadherin (heart))

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Keyword

Gene: CDH13 (cadherin 13, H-cadherin (heart)) Homo sapiens

Symbol:

CDH13

Name:

cadherin 13, H-cadherin (heart)

Description:

This gene encodes a member of the cadherin superfamily. The encoded protein is localized to the surface of the cell membrane and is anchored by a GPI moiety, rather than by a transmembrane domain. The protein lacks the cytoplasmic domain characteristic of other cadherins, and so is not thought to be a cell-cell adhesion glycoprotein. This protein acts as a negative regulator of axon growth during neural differentiation. It also protects vascular endothelial cells from apoptosis due to oxidative stress, and is associated with resistance to atherosclerosis. The gene is hypermethylated in many types of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2011]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

cadherin 13; cadherin-13; CDHH; H-cadherin; heart cadherin; heart-cadherin; P105; P105; T-cad; T-cadherin; truncated cadherin; truncated-cadherin

Orthologs:

Mus musculus : Cdh13 (cadherin 13) MGI
Rattus norvegicus : Cdh13 (cadherin 13)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	16	83,666,649 - 84,836,402	+	NCBI
Human Genome Assembly HuRef	16	68,413,614 - 69,581,731	+	NCBI
Human Genome Assembly GRCh37	16	82,660,399 - 83,830,215	+	NCBI
Human Genome Assembly Build 36	16	81,218,079 - 82,387,702	+	NCBI
Human Cytogenetic Map	16	q23.3		NCBI
Human Genome Assembly	16	81,218,078 - 82,387,698		NCBI