Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-demecolcine | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Demecolcine results in decreased expression of P2RX5 mRNA | CTD | PMID:23649840 | 17beta-estradiol | decreases expression | EXP | | 6480464 | Estradiol results in decreased expression of P2RX5 mRNA | CTD | PMID:19484750 | 17beta-estradiol | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Estradiol results in increased expression of P2RX5 mRNA | CTD | PMID:31614463 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Tetrachlorodibenzodioxin affects the expression of P2RX5 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of P2RX5 mRNA | CTD | PMID:33387578 | 3,3',5,5'-tetrabromobisphenol A | decreases expression | EXP | | 6480464 | tetrabromobisphenol A results in decreased expression of P2RX5 mRNA | CTD | PMID:25172293 | 4-hydroxynon-2-enal | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | 4-hydroxy-2-nonenal results in decreased expression of P2RX5 mRNA | CTD | PMID:12419474 | aflatoxin B1 | increases expression | EXP | | 6480464 | Aflatoxin B1 results in increased expression of P2RX5 mRNA | CTD | PMID:19770486 | all-trans-retinoic acid | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of P2RX5 mRNA | CTD | PMID:23724009 | ammonium chloride | affects expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of P2RX5 mRNA | CTD | PMID:16483693 | aristolochic acid A | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | aristolochic acid I results in increased expression of P2RX5 mRNA | CTD | PMID:33212167 | ATP | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | ATP affects transport ion flux of P2rx5 receptor | RGD | | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of P2RX5 mRNA | CTD | PMID:21569818 | benzo[a]pyrene | decreases methylation | ISO | P2RX5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of P2RX5 promoter | CTD | PMID:27901495 | benzo[a]pyrene | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of P2RX5 mRNA | CTD | PMID:20106945 more ... | benzo[b]fluoranthene | increases expression | EXP | | 6480464 | benzo(b)fluoranthene results in increased expression of P2RX5 mRNA | CTD | PMID:26377693 | bisphenol A | decreases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of P2RX5 mRNA | CTD | PMID:25181051 | cadmium dichloride | decreases expression | EXP | | 6480464 | Cadmium Chloride results in decreased expression of P2RX5 mRNA | CTD | PMID:24982889 | carbon nanotube | decreases expression | EXP | | 6480464 | Nanotubes and Carbon analog results in decreased expression of P2RX5 mRNA | CTD | PMID:25554681 | cisplatin | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in decreased expression of P2RX5 mRNA | CTD | PMID:27392435 | cisplatin | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of P2RX5 mRNA | CTD | PMID:27392435 | copper atom | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of P2RX5 mRNA | CTD | PMID:20971185 | copper(0) | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in decreased expression of P2RX5 mRNA | CTD | PMID:20971185 | corn oil | affects expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Corn Oil affects the expression of P2RX5 mRNA | CTD | PMID:16360708 | CTP | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | CTP affects transport ion flux of P2rx5 receptor | RGD | | cyclosporin A | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of P2RX5 mRNA | CTD | PMID:20106945 more ... | cyclosporin A | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of P2RX5 mRNA | CTD | PMID:27989131 | dextran sulfate | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P2RX5 mRNA | CTD | PMID:29950665 | diclofenac | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Diclofenac results in increased expression of P2RX5 mRNA | CTD | PMID:30723492 | dorsomorphin | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of P2RX5 mRNA | CTD | PMID:27188386 | doxorubicin | affects expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Doxorubicin affects the expression of P2RX5 mRNA | CTD | PMID:29803840 | endosulfan | decreases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of P2RX5 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | entinostat results in increased expression of P2RX5 mRNA | CTD | PMID:26272509 | entinostat | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of P2RX5 mRNA | CTD | PMID:27188386 | epoxiconazole | increases expression | EXP | | 6480464 | epoxiconazole results in increased expression of P2RX5 mRNA | CTD | PMID:35436446 | ethyl methanesulfonate | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Ethyl Methanesulfonate results in decreased expression of P2RX5 mRNA | CTD | PMID:23649840 | ethylparaben | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of P2RX5 mRNA | CTD | PMID:37690743 | fenvalerate | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of P2RX5 mRNA | CTD | PMID:30307764 | formaldehyde | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Formaldehyde results in decreased expression of P2RX5 mRNA | CTD | PMID:23649840 | genistein | increases expression | EXP | | 6480464 | Genistein results in increased expression of P2RX5 mRNA | CTD | PMID:32186404 | gentamycin | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of P2RX5 mRNA | CTD | PMID:33387578 | GTP | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | GTP affects transport ion flux of P2rx5 receptor | RGD | | indole-3-methanol | multiple interactions | ISO | P2rx5 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of P2RX5 mRNA | CTD | PMID:22129741 | lead(0) | affects expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Lead affects the expression of P2RX5 mRNA | CTD | PMID:28903495 | lipopolysaccharide | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of P2RX5 mRNA | CTD | PMID:35811015 | methyl methanesulfonate | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of P2RX5 mRNA | CTD | PMID:23649840 | methylmercury chloride | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of P2RX5 mRNA | CTD | PMID:28001369 | N-acetyl-L-cysteine | multiple interactions | ISO | P2rx5 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of P2RX5 mRNA | CTD | PMID:22129741 | N-methyl-4-phenylpyridinium | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | 1-Methyl-4-phenylpyridinium results in increased expression of P2RX5 mRNA | CTD | PMID:28801915 | N-nitrosodiethylamine | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Diethylnitrosamine results in increased expression of P2RX5 mRNA | CTD | PMID:19638242 | N-nitrosodiethylamine | multiple interactions | ISO | P2rx5 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of P2RX5 mRNA | CTD | PMID:22129741 | nickel atom | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Nickel results in increased expression of P2RX5 mRNA | CTD | PMID:25583101 | nucleoside pentaphosphate | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | diinosine pentaphosphate affects transport ion flux of P2rx5 receptor | RGD | | paracetamol | affects expression | EXP | | 6480464 | Acetaminophen affects the expression of P2RX5 mRNA | CTD | PMID:17562736 | paracetamol | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of P2RX5 mRNA | CTD | PMID:33387578 | paracetamol | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of P2RX5 mRNA | CTD | PMID:29067470 | paraquat | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Paraquat results in increased expression of P2RX5 mRNA | CTD | PMID:32680482 | phenylephrine | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Phenylephrine results in increased expression of P2RX5 mRNA | CTD | PMID:18158353 | potassium chromate | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of P2RX5 mRNA | CTD | PMID:22714537 | purinergic receptor P2X antagonist | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | PPADS CHEBI:34941 affects transport ion flux of P2rx5 receptor | RGD | | Reactive blue 2 | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | Reactive blue 2 affects transport ion flux of P2rx5 receptor | RGD | | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of P2RX5 mRNA | CTD | PMID:35811015 | SB 431542 | multiple interactions | ISO | P2RX5 (Homo sapiens) | 6480464 | [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of P2RX5 mRNA | CTD | PMID:27188386 | silicon dioxide | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in increased expression of P2RX5 mRNA | CTD | PMID:25895662 | sodium arsenite | decreases expression | EXP | | 6480464 | sodium arsenite results in decreased expression of P2RX5 mRNA | CTD | PMID:37682722 | sunitinib | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of P2RX5 mRNA | CTD | PMID:31533062 | suramin | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | Suramin affects transport ion flux of P2rx5 receptor | RGD | | tamibarotene | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | tamibarotene results in increased expression of P2RX5 mRNA | CTD | PMID:17229644 | tamoxifen | decreases expression | EXP | | 6480464 | Tamoxifen results in decreased expression of P2RX5 mRNA | CTD | PMID:25123088 | testosterone | decreases expression | EXP | | 6480464 | Testosterone deficiency results in decreased expression of P2RX5 mRNA | CTD | PMID:33848595 | testosterone | multiple interactions | EXP | | 6480464 | 1 more ... | CTD | PMID:33848595 | titanium dioxide | multiple interactions | EXP | | 6480464 | [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of P2RX5 mRNA | CTD | PMID:29950665 | TNP-ATP | affects transport | ISO | P2rx5 (Rattus norvegicus) | 727431 | TNP-ATP affects transport ion flux of P2rx5 receptor | RGD | | trichloroethene | increases expression | ISO | P2rx5 (Rattus norvegicus) | 6480464 | Trichloroethylene results in increased expression of P2RX5 mRNA | CTD | PMID:33387578 | valproic acid | increases methylation | ISO | P2RX5 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of P2RX5 gene | CTD | PMID:29154799 | valproic acid | increases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of P2RX5 mRNA | CTD | PMID:23179753 | vincristine | decreases expression | ISO | P2RX5 (Homo sapiens) | 6480464 | Vincristine results in decreased expression of P2RX5 mRNA | CTD | PMID:23649840 | |