SNAP25 (synaptosomal-associated protein, 25kDa)

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Keyword

Gene: SNAP25 (synaptosomal-associated protein, 25kDa) Homo sapiens

Symbol:

SNAP25

Name:

synaptosomal-associated protein, 25kDa

Description:

Synaptic vesicle membrane docking and fusion is mediated by SNAREs (soluble N-ethylmaleimide-sensitive factor attachment protein receptors) located on the vesicle membrane (v-SNAREs) and the target membrane (t-SNAREs). The assembled v-SNARE/t-SNARE complex consists of a bundle of four helices, one of which is supplied by v-SNARE and the other three by t-SNARE. For t-SNAREs on the plasma membrane, the protein syntaxin supplies one helix and the protein encoded by this gene contributes the other two. Therefore, this gene product is a presynaptic plasma membrane protein involved in the regulation of neurotransmitter release. Two alternative transcript variants encoding different protein isoforms have been described for this gene. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

bA416N4.2; dJ1068F16.2; FLJ23079; OTTHUMP00000030267; OTTHUMP00000030268; resistance to inhibitors of cholinesterase 4 homolog; RIC-4; RIC4; SEC9; SNAP; SNAP-25; SUP; super protein; synaptosomal-associated 25 kDa protein; synaptosomal-associated protein; synaptosomal-associated protein 25

Orthologs:

Mus musculus : Snap25 (synaptosomal-associated protein 25) MGI
Rattus norvegicus : Snap25 (synaptosomal-associated protein 25)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	20	10,147,418 - 10,236,106	+	NCBI
Human Genome Assembly HuRef	20	10,151,237 - 10,239,826	+	NCBI
Human Genome Assembly GRCh37	20	10,199,477 - 10,288,066	+	NCBI
Human Genome Assembly Build 36	20	10,147,477 - 10,236,065	+	NCBI
Human Cytogenetic Map	20	p12-p11.2		NCBI
Human Genome Assembly	20	10,147,476 - 10,236,065		NCBI