Gene: SPEG (SPEG complex locus)  Homo sapiens

Symbol: SPEG
Name: SPEG complex locus
Description: This gene encodes a protein with similarity to members of the myosin light chain kinase family. This protein family is required for myocyte cytoskeletal development. Studies in mouse have determined that a lack of this protein affected myocardial development. Multiple alternatively spliced transcript variants have been reported for this gene, but the full-length nature of only two variants that encode different protein isoforms has been defined. [provided by RefSeq, Mar 2010]
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: aortic preferentially expressed gene 1; aortic preferentially expressed protein 1; APEG-1; APEG-1; APEG1; BPEG; KIAA1297; MGC12676; nuclear protein, marker for differentiated aortic smooth muscle and down-regulated with vascular injury; OTTHUMP00000064868; OTTHUMP00000196351; OTTHUMP00000196352; OTTHUMP00000196353; SPEGalpha; SPEGbeta; striated muscle preferentially expressed protein kinase
Orthologs: Rattus norvegicus : Speg (SPEG complex locus)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_12219,680,216 - 219,738,800+NCBI
Human Genome Assembly HuRef2212,152,724 - 212,211,419+NCBI
Human Genome Assembly GRCh372220,299,700 - 220,358,354+NCBI
Human Celera Assembly2214,069,692 - 214,128,346+NCBI
Human Genome Assembly Build 362220,007,944 - 220,066,598+NCBI
Human Cytogenetic Map2q35 NCBI
Human Genome Assembly2220,133,900 - 220,157,088 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on SPEG
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 734132
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE