Gene: KCNH3 (potassium voltage-gated channel subfamily H member 3) Homo sapiens
Analyze
Symbol: KCNH3
Name: potassium voltage-gated channel subfamily H member 3
Description: The protein encoded by this gene is a voltage-gated potassium channel alpha subunit predominantly expressed in the forebrain. Studies in mice have found that cognitive function increases when this gene is knocked out. In humans, the encoded protein has been shown to be capable of binding glycoprotein 120 of the human immunodeficiency virus type 1 (HIV-1) envelope. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BEC1; brain-specific eag-like channel 1; ELK channel 2; ELK2; ether-a-go-go K(+) channel family member; ether-a-go-go-like potassium channel 2; KIAA1282; Kv12.2; OTTHUMP00000241404; potassium channel, voltage gated eag related subfamily H, member 3; potassium voltage-gated channel, subfamily H (eag-related), member 3; voltage-gated potassium channel subunit Kv12.2
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381249,538,541 - 49,558,312 (+)NCBIGRCh38hg38GRCh38
GRCh371249,932,834 - 49,952,091 (+)NCBIGRCh37hg19GRCh37
Build 361248,219,207 - 48,238,344 (+)NCBINCBI36hg18NCBI36
Build 341248,219,206 - 48,238,344NCBI
Celera1248,727,399 - 48,746,536 (+)NCBI
Cytogenetic Map12q13.12NCBImapview
HuRef1246,963,792 - 46,982,929 (+)NCBI
CHM1_11249,899,177 - 49,918,332 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on KCNH3
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 733984
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2017-09-05
Status: ACTIVE