Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 4,4'-sulfonyldiphenol | decreases expression | ISO | Kcnh4 (Mus musculus) | 6480464 | bisphenol S results in decreased expression of KCNH4 mRNA | CTD | PMID:30951980 | 4,4'-sulfonyldiphenol | increases methylation | ISO | Kcnh4 (Mus musculus) | 6480464 | bisphenol S results in increased methylation of KCNH4 exon | CTD | PMID:33297965 | 6-propyl-2-thiouracil | decreases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of KCNH4 mRNA | CTD | PMID:24780913 | acrylamide | affects expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Acrylamide affects the expression of KCNH4 mRNA | CTD | PMID:28959563 | all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of KCNH4 mRNA | CTD | PMID:33167477 | ammonium chloride | affects expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of KCNH4 mRNA | CTD | PMID:16483693 | benzo[a]pyrene | decreases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Benzo(a)pyrene results in decreased expression of KCNH4 mRNA | CTD | PMID:21839799 | benzo[a]pyrene | increases methylation | EXP | | 6480464 | Benzo(a)pyrene results in increased methylation of KCNH4 exon | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | EXP | | 6480464 | Benzo(a)pyrene affects the methylation of KCNH4 promoter | CTD | PMID:27901495 | benzo[e]pyrene | increases methylation | EXP | | 6480464 | benzo(e)pyrene results in increased methylation of KCNH4 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of KCNH4 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | increases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | bisphenol A results in increased expression of KCNH4 mRNA | CTD | PMID:34947998 | bisphenol A | decreases expression | ISO | Kcnh4 (Mus musculus) | 6480464 | bisphenol A results in decreased expression of KCNH4 mRNA | CTD | PMID:30951980 | bisphenol F | decreases expression | ISO | Kcnh4 (Mus musculus) | 6480464 | bisphenol F results in decreased expression of KCNH4 mRNA | CTD | PMID:30951980 | CGP 52608 | multiple interactions | EXP | | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to KCNH4 gene] | CTD | PMID:28238834 | chlorpyrifos | increases expression | ISO | Kcnh4 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of KCNH4 mRNA | CTD | PMID:32715474 | disodium selenite | decreases expression | EXP | | 6480464 | Sodium Selenite results in decreased expression of KCNH4 mRNA | CTD | PMID:18175754 | ethanol | decreases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Ethanol results in decreased expression of KCNH4 mRNA | CTD | PMID:15353170 | ethanol | affects expression | ISO | Kcnh4 (Mus musculus) | 6480464 | Ethanol affects the expression of KCNH4 mRNA | CTD | PMID:30319688 | gentamycin | increases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Gentamicins results in increased expression of KCNH4 mRNA | CTD | PMID:33387578 | ivermectin | increases expression | EXP | | 6480464 | Ivermectin results in increased expression of KCNH4 protein | CTD | PMID:32959892 | manganese(II) chloride | decreases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | manganese chloride results in decreased expression of KCNH4 mRNA | CTD | PMID:28801915 | methapyrilene | increases methylation | EXP | | 6480464 | Methapyrilene results in increased methylation of KCNH4 intron | CTD | PMID:30157460 | ozone | decreases expression | ISO | Kcnh4 (Mus musculus) | 6480464 | Ozone results in decreased expression of KCNH4 mRNA | CTD | PMID:33026818 | paracetamol | increases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of KCNH4 mRNA | CTD | PMID:33387578 | resveratrol | multiple interactions | EXP | | 6480464 | [Plant Extracts co-treated with Resveratrol] results in decreased expression of KCNH4 mRNA | CTD | PMID:23557933 | sodium arsenite | increases expression | EXP | | 6480464 | sodium arsenite results in increased expression of KCNH4 mRNA | CTD | PMID:29301061 and PMID:34032870 | trichloroethene | decreases expression | ISO | Kcnh4 (Rattus norvegicus) | 6480464 | Trichloroethylene results in decreased expression of KCNH4 mRNA | CTD | PMID:33387578 | triptonide | increases expression | ISO | Kcnh4 (Mus musculus) | 6480464 | triptonide results in increased expression of KCNH4 mRNA | CTD | PMID:33045310 | valproic acid | increases methylation | EXP | | 6480464 | Valproic Acid results in increased methylation of KCNH4 gene | CTD | PMID:29154799 | |