LTC4S (leukotriene C4 synthase) - Rat Genome Database

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Keyword

Gene: LTC4S (leukotriene C4 synthase) Homo sapiens

Symbol:

LTC4S

Name:

leukotriene C4 synthase

Description:

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

leukotriene C4 synthase; leukotriene-C(4) synthase; LTC4 synthase; MGC33147; OTTHUMP00000197039

Orthologs:

Mus musculus : Ltc4s (leukotriene C4 synthase) MGI
Rattus norvegicus : Ltc4s (leukotriene C4 synthase)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	5	179,441,410 - 179,443,937	+	NCBI
Human Genome Assembly HuRef	5	173,947,161 - 173,949,688	+	NCBI
Human Genome Assembly GRCh37	5	179,220,986 - 179,223,513	+	NCBI
Human Genome Assembly Build 36	5	179,153,592 - 179,156,119	+	NCBI
Human Cytogenetic Map	5	q35		NCBI
Human Genome Assembly	5	179,153,591 - 179,156,119		NCBI