Gene: CLCN2 (chloride voltage-gated channel 2) Homo sapiens
Analyze
Symbol: CLCN2
Name: chloride voltage-gated channel 2
Description: This gene encodes a voltage-gated chloride channel. The encoded protein is a transmembrane protein that maintains chloride ion homeostasis in various cells. Defects in this gene may be a cause of certain epilepsies. Four transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chloride channel 2; chloride channel protein 2; chloride channel, voltage-sensitive 2; CIC-2; clC-2; CLC2; ECA2; ECA3; EGI11; EGI3; EGMA; EJM6; EJM8; LKPAT; OTTHUMP00000210513; OTTHUMP00000210514; OTTHUMP00000210515; OTTHUMP00000210516
Orthologs:
Mus musculus (house mouse) : Clcn2 (chloride channel, voltage-sensitive 2)  MGI
Rattus norvegicus (Norway rat) : Clcn2 (chloride voltage-gated channel 2)
Chinchilla lanigera (long-tailed chinchilla) : Clcn2 (chloride voltage-gated channel 2)
Pan paniscus (bonobo/pygmy chimpanzee) : CLCN2 (chloride voltage-gated channel 2)
Canis lupus familiaris (dog) : CLCN2 (chloride voltage-gated channel 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Clcn2 (chloride voltage-gated channel 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383184,346,185 - 184,361,651 (-)NCBIGRCh38hg38GRCh38
GRCh373184,063,973 - 184,079,439 (-)NCBIGRCh37hg19GRCh37
Build 363185,547,034 - 185,562,085 (-)NCBINCBI36hg18NCBI36
Build 343185,547,095 - 185,561,969NCBI
Celera3182,504,875 - 182,520,290 (-)NCBI
Cytogenetic Map3q27.1NCBImapview
HuRef3181,470,404 - 181,485,871 (-)NCBI
CHM1_13184,028,432 - 184,043,898 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CLCN2
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 733366
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2017-09-05
Status: ACTIVE