Gene: Top1 (topoisomerase (DNA) I)  Mus musculus

Symbol: Top1
Name: topoisomerase (DNA) I
Description: ENCODES a protein that exhibits DNA topoisomerase type I activity; chromatin binding (ortholog); chromatin DNA binding (ortholog); INVOLVED IN DNA replication; DNA topological change; embryonic cleavage; ASSOCIATED WITH complete embryonic lethality before implantation; FOUND IN cytoplasm; nucleus; perikaryon; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; 3'-deamino-3'-(3-cyanomorpholin-4-yl)doxorubicin
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI467334; D130064I21Rik; DNA topoisomerase 1; DNA topoisomerase I; OTTMUSP00000001137; Top-1
Orthologs: Homo sapiens : TOP1 (topoisomerase (DNA) I)  HGNC
Rattus norvegicus : Top1 (topoisomerase (DNA) I)
Latest Assembly: Mouse Genome Assembly Build 37
Position:
MapChrPositionStrandSource
Mouse Genome Assembly GRCm382160,645,897 - 160,722,764+NCBI
Mouse cM Map280.96 NCBI
Mouse Celera Assembly2166,577,915 - 166,654,823+NCBI
Mouse Genome Assembly Build 372160,471,633 - 160,548,500+NCBI
Mouse Genome Assembly Build 36.12160,471,633 - 160,548,500+NCBI
Mouse Cytogenetic Map2 H2-3 NCBI
Model

Launch Genome Browser (GBrowse)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Mouse Genome Assembly Build 37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Top1
Entrez Gene
Ensembl Gene
Genome Browser
MGI Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 733199
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2013-04-23
Status: ACTIVE