Gene: TALDO1 (transaldolase 1)  Homo sapiens

Symbol: TALDO1
Name: transaldolase 1
Description: Transaldolase 1 is a key enzyme of the nonoxidative pentose phosphate pathway providing ribose-5-phosphate for nucleic acid synthesis and NADPH for lipid biosynthesis. This pathway can also maintain glutathione at a reduced state and thus protect sulfhydryl groups and cellular integrity from oxygen radicals. The functional gene of transaldolase 1 is located on chromosome 11 and a pseudogene is identified on chromosome 1 but there are conflicting map locations. The second and third exon of this gene were developed by insertion of a retrotransposable element. This gene is thought to be involved in multiple sclerosis. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: dihydroxyacetone transferase; glycerone transferase; OTTHUMP00000164441; OTTHUMP00000229014; TAL; TAL-H; TALDOR; TALH; transaldolase
Orthologs: Mus musculus : Taldo1 (transaldolase 1)  MGI
Rattus norvegicus : Taldo1 (transaldolase 1)
Related Pseudogenes: TALDO1P1  
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_111684,024 - 701,622+NCBI
Human Genome Assembly HuRef11564,412 - 581,950+NCBI
Human Genome Assembly GRCh3711747,432 - 765,024+NCBI
Human Genome Assembly Build 3611737,432 - 755,024+NCBI
Human Cytogenetic Map11p15.5-p15.4 NCBI
Human Genome Assembly11737,431 - 755,023 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on TALDO1
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 733188
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2013-03-05
Status: ACTIVE