Gene: HCN2 (hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2) Homo sapiens
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Symbol: HCN2
Name: hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
Description: The protein encoded by this gene is a hyperpolarization-activated cation channel involved in the generation of native pacemaker activity in the heart and in the brain. The encoded protein is activated by cAMP and can produce a fast, large current. Defects in this gene were noted as a possible cause of some forms of epilepsy. [provided by RefSeq, Jan 2017]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BCNG-2; BCNG2; brain cyclic nucleotide gated channel 2; brain cyclic nucleotide-gated channel 2; HAC-1; hyperpolarization activated cyclic nucleotide gated potassium channel 2; hyperpolarization activated cyclic nucleotide-gated potassium channel 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3819589,893 - 617,159 (+)NCBIGRCh38hg38GRCh38
GRCh3719589,893 - 617,159 (+)NCBIGRCh37hg19GRCh37
Build 3619540,893 - 568,159 (+)NCBINCBI36hg18NCBI36
Build 3419540,892 - 568,157NCBI
Celera19200,463 - 228,092 (-)NCBI
Cytogenetic Map19p13.3NCBImapview
HuRef19373,968 - 384,301 (+)NCBI
CHM1_119589,749 - 616,575 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


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References - uncurated
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Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on HCN2
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
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RGD Object Information
RGD ID: 732305
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2017-06-13
Status: ACTIVE