Gene: SLC1A2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2)  Homo sapiens
Symbol: SLC1A2
Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Description: This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Sep 2010]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EAAT2; excitatory amino acid transporter 2; excitotoxic amino acid transporter 2; glial high affinity glutamate transporter; GLT-1; glutamate/aspartate transporter II; OTTHUMP00000165208; OTTHUMP00000165209; OTTHUMP00000165210; sodium-dependent glutamate/aspartate transporter 2; solute carrier family 1 member 2; solute carrier family 1, member 2
Orthologs: Mus musculus : Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2)  MGI
Rattus norvegicus : Slc1a2 (solute carrier family 1 (glial high affinity glutamate transporter), member 2)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11135,201,317 - 35,369,997-NCBI
Human Genome Assembly HuRef1134,972,036 - 35,140,670-NCBI
Human Genome Assembly GRCh371135,272,752 - 35,441,610-NCBI
Human Genome Assembly Build 361135,229,328 - 35,397,681-NCBI
Human Cytogenetic Map11p13-p12 NCBI
Human Genome Assembly1135,229,328 - 35,397,372 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)

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Genomics

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QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
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Additional Information

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Nomenclature History
  
More on SLC1A2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 732300
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2013-04-09
Status: ACTIVE



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