Gene: KCNMA1 (potassium calcium-activated channel subfamily M alpha 1) Homo sapiens
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Symbol: KCNMA1
Name: potassium calcium-activated channel subfamily M alpha 1
Description: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bA205K10.1; big potassium channel alpha subunit; BK channel; BK channel alpha subunit; BKCA alpha subunit; BKTM; CADEDS; calcium-activated potassium channel subunit alpha-1; calcium-activated potassium channel, subfamily M subunit alpha-1; DKFZp686K1437; Drosophila slowpoke-like; hSlo; k(VCA)alpha; KCa1.1; maxi K channel; maxi-K channel HSLO; MaxiK; MGC71881; mSLO1; OTTHUMP00000019904; OTTHUMP00000019905; OTTHUMP00000019906; OTTHUMP00000019907; OTTHUMP00000019908; OTTHUMP00000019909; OTTHUMP00000019910; OTTHUMP00000019911; OTTHUMP00000019912; OTTHUMP00000019913; OTTHUMP00000019914; PNKD3; potassium channel, calcium activated large conductance subfamily M alpha, member 1; potassium large conductance calcium-activated channel, subfamily M, alpha member 1; SAKCA; SLO; slo homolog; SLO-ALPHA; SLO1; slowpoke homolog; stretch-activated Kca channel
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381076,869,601 - 77,637,819 (-)NCBIGRCh38hg38GRCh38
GRCh371078,629,359 - 79,397,577 (-)NCBIGRCh37hg19GRCh37
Build 361078,299,366 - 79,067,583 (-)NCBINCBI36hg18NCBI36
Build 341078,314,640 - 79,067,583NCBI
Celera1071,914,113 - 72,684,182 (-)NCBI
Cytogenetic Map10q22.3NCBImapview
HuRef1072,624,294 - 73,391,824 (-)NCBI
CHM1_11078,911,952 - 79,680,009 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
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Sequence

Nucleotide Sequences
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Additional Information

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Nomenclature History
 
More on KCNMA1
AGR Gene
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RGD Object Information
RGD ID: 731981
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2017-11-17
Status: ACTIVE