Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ERC1 mRNA | CTD | PMID:22079256 | (1->4)-beta-D-glucan | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ERC1 mRNA | CTD | PMID:36331819 | 17beta-estradiol | affects expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Estradiol affects the expression of ERC1 mRNA | CTD | PMID:32145629 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ERC1 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of ERC1 mRNA | CTD | PMID:33387578 and PMID:34747641 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ERC1 mRNA | CTD | PMID:21570461 | 2,3,7,8-Tetrachlorodibenzofuran | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | 2 more ... | CTD | PMID:32109520 | 2,5-hexanedione | increases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | 2 and 5-hexanedione results in increased expression of ERC1 mRNA | CTD | PMID:22952946 | 3,3',4,4'-tetrachlorobiphenyl | multiple interactions | EXP | | 6480464 | 3 more ... | CTD | PMID:19467301 | 4,4'-sulfonyldiphenol | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | bisphenol S results in increased expression of ERC1 protein | CTD | PMID:34186270 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of ERC1 mRNA | CTD | PMID:28973697 | 5-aza-2'-deoxycytidine | affects expression | ISO | ERC1 (Homo sapiens) | 6480464 | Decitabine affects the expression of ERC1 mRNA | CTD | PMID:23300844 | acetamide | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | acetamide results in decreased expression of ERC1 mRNA | CTD | PMID:31881176 | acrolein | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ERC1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ERC1 mRNA | CTD | PMID:32699268 | aflatoxin B1 | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased expression of ERC1 mRNA | CTD | PMID:21641981 | aflatoxin B1 | increases methylation | ISO | ERC1 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of ERC1 gene | CTD | PMID:27153756 | Aflatoxin B2 alpha | decreases methylation | ISO | ERC1 (Homo sapiens) | 6480464 | aflatoxin B2 results in decreased methylation of ERC1 intron | CTD | PMID:30157460 | alpha-pinene | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ERC1 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of ERC1 mRNA | CTD | PMID:32699268 | ammonium chloride | affects expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Ammonium Chloride affects the expression of ERC1 mRNA | CTD | PMID:16483693 | amphetamine | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Amphetamine results in decreased expression of ERC1 mRNA | CTD | PMID:30779732 | aristolochic acid A | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of ERC1 mRNA | CTD | PMID:33212167 | arsenite(3-) | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to ERC1 mRNA] | CTD | PMID:32406909 | arsenous acid | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of ERC1 mRNA | CTD | PMID:20458559 | benzo[a]pyrene | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of ERC1 mRNA | CTD | PMID:20064835 more ... | benzo[a]pyrene | affects methylation | ISO | ERC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ERC1 intron | CTD | PMID:30157460 | benzo[a]pyrene | increases methylation | ISO | ERC1 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ERC1 5' UTR | CTD | PMID:27901495 | benzo[a]pyrene diol epoxide I | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:20018196 more ... | benzo[e]pyrene | decreases methylation | ISO | ERC1 (Homo sapiens) | 6480464 | benzo(e)pyrene results in decreased methylation of ERC1 intron | CTD | PMID:30157460 | bisphenol A | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ERC1 mRNA | CTD | PMID:25181051 and PMID:30816183 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ERC1 mRNA | CTD | PMID:37894381 | bisphenol A | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ERC1 gene | CTD | PMID:31601247 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of ERC1 mRNA | CTD | PMID:38074096 | bisphenol A | affects expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | bisphenol A affects the expression of ERC1 mRNA | CTD | PMID:32145629 | bisphenol A | increases methylation | ISO | Erc1 (Rattus norvegicus) | 6480464 | bisphenol A results in increased methylation of ERC1 gene | CTD | PMID:28505145 | Bisphenol B | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | bisphenol B results in increased expression of ERC1 protein | CTD | PMID:34186270 | bisphenol F | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [bisphenol F co-treated with Fulvestrant] results in increased methylation of ERC1 gene | CTD | PMID:31601247 | cadmium dichloride | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Cadmium Chloride results in increased expression of ERC1 mRNA | CTD | PMID:26472689 | caffeine | decreases phosphorylation | ISO | ERC1 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of ERC1 protein | CTD | PMID:35688186 | CGP 52608 | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to ERC1 gene] | CTD | PMID:28238834 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of ERC1 mRNA | CTD | PMID:37019170 | cisplatin | affects expression | ISO | ERC1 (Homo sapiens) | 6480464 | Cisplatin affects the expression of ERC1 mRNA | CTD | PMID:23300844 | clofibrate | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Clofibrate results in decreased expression of ERC1 mRNA | CTD | PMID:12851107 | diarsenic trioxide | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Arsenic Trioxide results in decreased expression of ERC1 mRNA | CTD | PMID:20458559 | dicrotophos | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | dicrotophos results in increased expression of ERC1 mRNA | CTD | PMID:28302478 | endosulfan | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Endosulfan results in decreased expression of ERC1 mRNA | CTD | PMID:29391264 | entinostat | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | entinostat results in increased expression of ERC1 mRNA | CTD | PMID:27188386 | epoxiconazole | decreases expression | EXP | | 6480464 | epoxiconazole results in decreased expression of ERC1 mRNA | CTD | PMID:35436446 | ethanol | affects splicing | EXP | | 6480464 | Ethanol affects the splicing of ERC1 mRNA | CTD | PMID:30319688 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of ERC1 mRNA | CTD | PMID:25629700 | FR900359 | increases phosphorylation | ISO | ERC1 (Homo sapiens) | 6480464 | FR900359 results in increased phosphorylation of ERC1 protein | CTD | PMID:37730182 | fulvestrant | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of ERC1 gene and [bisphenol F co-treated with Fulvestrant] results in increased methylation of ERC1 gene | CTD | PMID:31601247 | genistein | decreases expression | EXP | | 6480464 | Genistein results in decreased expression of ERC1 mRNA | CTD | PMID:32186404 | geraniol | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | geraniol results in increased expression of ERC1 mRNA | CTD | PMID:27683099 | glycidol | decreases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | glycidol results in decreased expression of ERC1 mRNA | CTD | PMID:24915197 | hydroquinone O-beta-D-glucopyranoside | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Arbutin results in increased expression of ERC1 mRNA | CTD | PMID:17103032 | irinotecan | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Irinotecan analog results in decreased expression of ERC1 mRNA | CTD | PMID:18927307 | ivermectin | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Ivermectin results in decreased expression of ERC1 protein | CTD | PMID:32959892 | ketoconazole | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Ketoconazole results in decreased expression of ERC1 mRNA | CTD | PMID:36621641 | methapyrilene | decreases methylation | ISO | ERC1 (Homo sapiens) | 6480464 | Methapyrilene results in decreased methylation of ERC1 intron | CTD | PMID:30157460 | methoxychlor | affects methylation | ISO | Erc1 (Rattus norvegicus) | 6480464 | Methoxychlor affects the methylation of ERC1 gene | CTD | PMID:35440735 | N,N-diethyl-m-toluamide | multiple interactions | ISO | Erc1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ERC1 gene | CTD | PMID:33148267 | N-nitrosodiethylamine | increases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Diethylnitrosamine results in increased expression of ERC1 mRNA | CTD | PMID:20360939 | nickel atom | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Nickel results in decreased expression of ERC1 mRNA | CTD | PMID:25583101 | ozone | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of ERC1 mRNA more ... | CTD | PMID:32699268 | paracetamol | increases expression | ISO | Erc1 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of ERC1 mRNA | CTD | PMID:33387578 | perfluorooctane-1-sulfonic acid | multiple interactions | EXP | | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of ERC1 mRNA | CTD | PMID:36331819 | permethrin | multiple interactions | ISO | Erc1 (Rattus norvegicus) | 6480464 | [Permethrin co-treated with DEET] results in increased methylation of ERC1 gene | CTD | PMID:33148267 | pinostrobin | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | pinostrobin results in increased expression of ERC1 mRNA | CTD | PMID:37777166 | pirinixic acid | increases expression | EXP | | 6480464 | pirinixic acid results in increased expression of ERC1 mRNA | CTD | PMID:18301758 | potassium chromate | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of ERC1 mRNA | CTD | PMID:22079256 | potassium chromate | multiple interactions | ISO | ERC1 (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of ERC1 mRNA | CTD | PMID:22079256 | sunitinib | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ERC1 mRNA | CTD | PMID:31533062 | testosterone enanthate | affects expression | ISO | ERC1 (Homo sapiens) | 6480464 | testosterone enanthate affects the expression of ERC1 mRNA | CTD | PMID:17440010 | thimerosal | decreases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Thimerosal results in decreased expression of ERC1 mRNA | CTD | PMID:27188386 | torcetrapib | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | torcetrapib results in increased expression of ERC1 mRNA | CTD | PMID:23228038 | triptonide | affects expression | EXP | | 6480464 | triptonide affects the expression of ERC1 mRNA | CTD | PMID:33045310 | valproic acid | affects expression | EXP | | 6480464 | Valproic Acid affects the expression of ERC1 mRNA | CTD | PMID:17292431 | valproic acid | increases expression | EXP | | 6480464 | Valproic Acid results in increased expression of ERC1 mRNA | CTD | PMID:21427059 | valproic acid | affects expression | ISO | ERC1 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of ERC1 mRNA | CTD | PMID:25979313 | valproic acid | increases expression | ISO | ERC1 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of ERC1 mRNA | CTD | PMID:19101580 more ... | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Gene Ontology Annotations Click to see Annotation Detail View
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References
References - curated
| # | Reference Title | Reference Citation |
| 1. | Functional annotation of a full-length mouse cDNA collection. | Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90. |
| 2. | MGDs mouse GO annotations | MGD data from the GO Consortium |
| 3. | Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. | Okazaki N, etal., DNA Res 2003 Feb 28;10(1):35-48. |
| 4. | Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. | Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73. |
| 5. | PID Annotation Import Pipeline | Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 6. | Mouse MP Annotation Import Pipeline | RGD automated import pipeline |
| 7. | ClinVar Automated Import and Annotation Pipeline | RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations |
| 8. | Data Import for Chemical-Gene Interactions | RGD automated import pipeline for gene-chemical interactions |
Additional References at PubMed
| PMID:8889548 | PMID:10349636 | PMID:10922068 | PMID:11042159 | PMID:11076861 | PMID:11929610 | PMID:12477932 | PMID:12520002 | PMID:12904583 | PMID:14610273 | PMID:14723704 | PMID:16141072 |
| PMID:16141073 | PMID:16944949 | PMID:16959763 | PMID:17124501 | PMID:18799693 | PMID:19555761 | PMID:20932476 | PMID:21228161 | PMID:21267068 | PMID:21873635 | PMID:22794259 | PMID:23791195 |
| PMID:23960145 | PMID:24194600 | PMID:25209271 | PMID:27224062 | PMID:27253063 | PMID:27537483 | PMID:27626661 | PMID:27889896 | PMID:28264913 | PMID:28671696 | PMID:29398114 | PMID:29491150 |
| PMID:29996090 | PMID:30157441 | PMID:30190286 | PMID:30699350 | PMID:30713523 | PMID:30995482 | PMID:31138677 | PMID:31537859 | PMID:31609468 | PMID:31996256 | PMID:32325033 | PMID:32521280 |
| PMID:32937583 | PMID:35006275 | PMID:35176221 | PMID:36179691 | PMID:36398873 | PMID:36417873 |
Genomics
Comparative Map Data
| Erc1 (Mus musculus - house mouse) |
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| ERC1 (Homo sapiens - human) |
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| Erc1 (Rattus norvegicus - Norway rat) |
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| Erc1 (Chinchilla lanigera - long-tailed chinchilla) |
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| ERC1 (Pan paniscus - bonobo/pygmy chimpanzee) |
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| ERC1 (Canis lupus familiaris - dog) |
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| Erc1 (Ictidomys tridecemlineatus - thirteen-lined ground squirrel) |
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| ERC1 (Sus scrofa - pig) |
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| ERC1 (Chlorocebus sabaeus - green monkey) |
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| Erc1 (Heterocephalus glaber - naked mole-rat) |
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Variants
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Variants in Erc1
7736 total Variants 
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