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Gene-Chemical Interaction Annotations
Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of HOXA2 mRNA | CTD | PMID:17942748 | 17alpha-ethynylestradiol | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HOXA2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | EXP | | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of HOXA2 mRNA | CTD | PMID:17942748 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of HOXA2 mRNA | CTD | PMID:21570461 | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of HOXA2 mRNA | CTD | PMID:19933214 | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of HOXA2 mRNA | CTD | PMID:19897914 | all-trans-retinoic acid | increases expression | ISO | RGD:1353431 | 6480464 | Tretinoin results in increased expression of HOXA2 mRNA | CTD | PMID:17185360 | all-trans-retinoic acid | increases expression | ISO | RGD:1353431 | 6480464 | Tretinoin results in increased expression of HOXA2 mRNA | CTD | PMID:17185360 PMID:21934132 | all-trans-retinoic acid | increases expression | ISO | RGD:1353431 | 6480464 | Tretinoin results in increased expression of HOXA2 mRNA | CTD | PMID:21934132 PMID:17185360 | ammonium chloride | affects expression | ISO | RGD:2813 | 6480464 | Ammonium Chloride affects the expression of HOXA2 mRNA | CTD | PMID:16483693 | bis(2-chloroethyl) sulfide | decreases expression | EXP | | 6480464 | Mustard Gas results in decreased expression of HOXA2 mRNA | CTD | PMID:15674843 | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of HOXA2 mRNA | CTD | PMID:22687993 | chloroprene | decreases expression | EXP | | 6480464 | Chloroprene results in decreased expression of HOXA2 mRNA | CTD | PMID:23125180 | cytarabine | increases expression | ISO | RGD:1353431 | 6480464 | Cytarabine results in increased expression of HOXA2 mRNA | CTD | PMID:21198554 | D-glucose | increases expression | ISO | RGD:2813 | 6480464 | Glucose results in increased expression of HOXA2 mRNA | CTD | PMID:21818840 | dimethylarsinic acid | decreases expression | ISO | RGD:2813 | 6480464 | Cacodylic Acid results in decreased expression of HOXA2 mRNA | CTD | PMID:16122865 | fonofos | increases methylation | ISO | RGD:1353431 | 6480464 | Fonofos results in increased methylation of HOXA2 promoter | CTD | PMID:22847954 | glucose | increases expression | ISO | RGD:2813 | 6480464 | Glucose results in increased expression of HOXA2 mRNA | CTD | PMID:21818840 | L-ascorbic acid | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [Valproic Acid results in decreased expression of HOXA2 mRNA] | CTD | PMID:19655241 | parathion | increases methylation | ISO | RGD:1353431 | 6480464 | Parathion results in increased methylation of HOXA2 promoter | CTD | PMID:22847954 | phenytoin | decreases expression | EXP | | 6480464 | Phenytoin results in decreased expression of HOXA2 mRNA; more ... | CTD | PMID:10789828 | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of HOXA2 mRNA | CTD | PMID:22698814 | terbufos | increases methylation | ISO | RGD:1353431 | 6480464 | terbufos results in increased methylation of HOXA2 promoter | CTD | PMID:22847954 | titanium dioxide | decreases expression | EXP | | 6480464 | titanium dioxide results in decreased expression of HOXA2 mRNA | CTD | PMID:23409001 | troglitazone | decreases expression | ISO | RGD:1353431 | 6480464 | troglitazone results in decreased expression of HOXA2 mRNA | CTD | PMID:19140230 | valproic acid | decreases expression | EXP | | 6480464 | Valproic Acid results in decreased expression of HOXA2 mRNA; more ... | CTD | PMID:19655241 | valproic acid | multiple interactions | EXP | | 6480464 | Ascorbic Acid inhibits the reaction [Valproic Acid results in decreased expression of HOXA2 mRNA] | CTD | PMID:19655241 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Phenotype Annotations
Disease Annotations
Gene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Phenotype Annotations
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References - curated| 1. |
Collins EC, etal., Mol Cell Biol 2002 Oct;22(20):7313-24. |
| 2. |
MGD and Homologene mouse data transfer |
| 3. |
MGD data from the GO Consortium |
| 4. |
MGD IEA |
| 5. |
RGD automated import pipeline |
| 6. |
RGD automated import pipeline for gene-chemical interactions |
| 7. |
RGD Automated Pipelines |
References - uncurated| PubMed | 10068641 |
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RGD Disease Portals| Hoxa2 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Hoxa2 (Mus musculus) |
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| HOXA2 (Homo sapiens) |
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| Hoxa2 (Rattus norvegicus) |
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Position Markers| Hoxa9 |
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| M95599 |
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| AI324701 |
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| ECD09887 |
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| REN100339 |
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| REN100338 |
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| ECD00644 |
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| Hoxa2 |
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| Hoxa2 |
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| Hoxa2 |
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QTLs in Region (Mouse Genome Assembly Build 37)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_010451 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AAHY01053339 | (Get FASTA) | Search GEO for Microarray Profiles |
| AB039184 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039185 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039186 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039187 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039188 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039189 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039190 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039191 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB039192 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AB221621 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AC091106 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK134501 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AK157713 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC027688 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC117105 | (Get FASTA) | Search GEO for Microarray Profiles | |
| BC117107 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH466597 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M87801 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M93148 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M93292 | (Get FASTA) | Search GEO for Microarray Profiles | |
| M95599 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_010451 | |||||||||||||||||||||||||
| RefSeq Status: | REVIEWED | |||||||||||||||||||||||||
| Type: | CODING | |||||||||||||||||||||||||
| Protein Acc Id: | NP_034581 | |||||||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_034581 | (Get FASTA) |
| GenBank Protein | AAA37827 | (Get FASTA) |
| AAA37834 | (Get FASTA) | |
| AAA37835 | (Get FASTA) | |
| AAA37836 | (Get FASTA) | |
| AAI17106 | (Get FASTA) | |
| AAI17108 | (Get FASTA) | |
| BAB68708 | (Get FASTA) | |
| BAB68709 | (Get FASTA) | |
| BAB68710 | (Get FASTA) | |
| BAB68711 | (Get FASTA) | |
| BAB68712 | (Get FASTA) | |
| BAB68713 | (Get FASTA) | |
| BAB68714 | (Get FASTA) | |
| BAB68715 | (Get FASTA) | |
| BAB68716 | (Get FASTA) | |
| BAE22163 | (Get FASTA) | |
| EDK98649 | (Get FASTA) | |
| P31245 | (Get FASTA) |
Promoters| RGD ID: | 6839454 | ||||||||||
| Promoter ID: | MM_KWN:45999 | ||||||||||
| Type: | CpG-Island | ||||||||||
| SO ACC ID: | SO:0000170 | ||||||||||
| Source: | MPROMDB | ||||||||||
| Tissues & Cell Lines: | 3T3L1_Day1, 3T3L1_Day2, Lung | ||||||||||
| Transcripts: | OTTMUST00000045381 | ||||||||||
| Position: |
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSMUSG00000014704 | |
| Entrez Gene | 15399 | ENTREZGENE |
| Gene3D-CATH | Homeodomain-rel | UniProtKB/Swiss-Prot |
| Germonline | ENSMUSG00000014704 | |
| HomoloGene Group ID | 4901 | ENTREZGENE |
| InterPro | Homeobox | UniProtKB/Swiss-Prot |
| Homeobox_Antennapedia_CS | UniProtKB/Swiss-Prot | |
| Homeobox_CS | UniProtKB/Swiss-Prot | |
| Homeobox_eu | UniProtKB/Swiss-Prot | |
| Homeodomain-like | UniProtKB/Swiss-Prot | |
| KEGG Report | mmu:15399 | ENTREZGENE, UniProtKB/Swiss-Prot |
| MGD | MGI:96174 | ENTREZGENE |
| Pfam | Homeobox | UniProtKB/Swiss-Prot |
| PRINTS | HOMEOBOX | UniProtKB/Swiss-Prot |
| PROSITE | ANTENNAPEDIA | UniProtKB/Swiss-Prot |
| HOMEOBOX_1 | UniProtKB/Swiss-Prot | |
| HOMEOBOX_2 | UniProtKB/Swiss-Prot | |
| SMART | HOX | UniProtKB/Swiss-Prot |
| Superfamily-SCOP | Homeodomain_like | UniProtKB/Swiss-Prot |
| UniGene | Mm.131 | ENTREZGENE |
| UniProt | HXA2_MOUSE | UniProtKB/Swiss-Prot |
| Q3UYP9_MOUSE | UniProtKB/TrEMBL |
| More on Hoxa2 | |
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Entrez Gene |
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Ensembl Gene |
![]() | Genome Browser |
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MGI Report |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 731539 |
| Created: | 2004-01-12 |
| Species: | Mus musculus |
| Last Modified: | 2013-03-26 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




