Gnai3 (G protein subunit alpha i3) - Rat Genome Database

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Gene: Gnai3 (G protein subunit alpha i3) Mus musculus
Analyze
Symbol: Gnai3
Name: G protein subunit alpha i3 (Ensembl:guanine nucleotide binding protein (G protein), alpha inhibiting 3)
RGD ID: 731004
MGI Page MGI
Description: Predicted to enable several functions, including G-protein beta/gamma-subunit complex binding activity; GDP binding activity; and GTPase activating protein binding activity. Predicted to be involved in several processes, including GTP metabolic process; positive regulation of superoxide anion generation; and positive regulation of vascular associated smooth muscle cell proliferation. Predicted to act upstream of or within G protein-coupled receptor signaling pathway. Located in Golgi apparatus. Is expressed in early conceptus; inner ear; and oocyte. Orthologous to human GNAI3 (G protein subunit alpha i3).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: AI158965; AW537698; g(i) alpha-3; Gal; Galphai3; Gnai-3; guanine nucleotide binding protein (G protein), alpha inhibiting 3; guanine nucleotide binding protein, alpha inhibiting 3; guanine nucleotide-binding protein G(i) subunit alpha; guanine nucleotide-binding protein G(i) subunit alpha-3; guanine nucleotide-binding protein G(k) subunit alpha; heterotrimeric guanine nucleotide-binding protein 1a; Hg1a
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm19189  
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393108,014,591 - 108,053,468 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3108,014,596 - 108,053,462 (-)EnsemblGRCm39 Ensembl
GRCm383108,107,275 - 108,146,152 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,107,280 - 108,146,146 (-)EnsemblGRCm38mm10GRCm38
MGSCv373107,910,217 - 107,949,032 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363108,235,355 - 108,274,170 (-)NCBIMGSCv36mm8
Celera3110,441,104 - 110,479,940 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
cM Map346.83NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(R,R,R)-alpha-tocopherol  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,6-dinitrotoluene  (ISO)
2-(4-iodo-2,5-dimethoxyphenyl)-1-methylethylamine  (EXP)
2-hydroxypropanoic acid  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
6-propyl-2-thiouracil  (ISO)
7,9-dihydro-1H-purine-2,6,8(3H)-trione  (ISO)
8-Br-cAMP  (ISO)
aldehydo-D-glucose  (ISO)
amitrole  (ISO)
ammonium chloride  (ISO)
amphetamine  (ISO)
Aroclor 1254  (EXP)
arsenite(3-)  (ISO)
arsenous acid  (ISO)
beauvericin  (ISO)
benzo[a]pyrene  (ISO)
biochanin A  (ISO)
bisphenol A  (ISO)
bortezomib  (ISO)
calciol  (EXP)
carbon nanotube  (EXP)
chlorpyrifos  (ISO)
cholesterol  (ISO)
clobetasol  (EXP)
clofibrate  (EXP)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
clozapine  (ISO)
cobalt dichloride  (ISO)
colforsin daropate hydrochloride  (ISO)
copper(II) sulfate  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenziodolium  (ISO)
dibutyl phthalate  (EXP)
dicrotophos  (ISO)
diuron  (ISO)
doxorubicin  (ISO)
enniatin  (ISO)
ethanol  (EXP)
flutamide  (ISO)
folic acid  (EXP)
genistein  (ISO)
gentamycin  (ISO)
glucose  (ISO)
Guanabenz  (EXP)
guanosine 5'-[gamma-thio]triphosphate  (EXP)
haloperidol  (ISO)
hypochlorous acid  (EXP)
ivermectin  (ISO)
lipopolysaccharide  (EXP)
methimazole  (ISO)
methoxychlor  (ISO)
N-acetyl-L-cysteine  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
nefazodone  (ISO)
nitroprusside  (ISO)
paracetamol  (EXP,ISO)
paraquat  (ISO)
pentachlorophenol  (EXP)
peroxynitrous acid  (ISO)
phenobarbital  (EXP)
potassium dichromate  (ISO)
progesterone  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
reserpine  (ISO)
resveratrol  (ISO)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
SB 431542  (ISO)
sirolimus  (EXP)
Soman  (ISO)
streptozocin  (ISO)
sulfadimethoxine  (ISO)
temozolomide  (ISO)
tetrachloromethane  (EXP)
thapsigargin  (ISO)
thioacetamide  (ISO)
trichloroethene  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)
vinclozolin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Losartan-induced attenuation of blood pressure in L-NAME hypertensive rats is associated with reversal of the enhanced expression of Gi alpha proteins. Hashim S and Anand-Srivastava MB, J Hypertens. 2004 Jan;22(1):181-90.
2. Molecular cloning of five GTP-binding protein cDNA species from rat olfactory neuroepithelium. Jones DT and Reed RR, J Biol Chem 1987 Oct 15;262(29):14241-9.
3. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
4. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. AT2 receptors: beneficial counter-regulatory role in cardiovascular and renal function. Padia SH and Carey RM, Pflugers Arch. 2013 Jan;465(1):99-110. doi: 10.1007/s00424-012-1146-3. Epub 2012 Sep 5.
9. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
10. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
11. Mouse MP Annotation Import Pipeline RGD automated import pipeline
12. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
13. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
14. [Alterations of cardiac Gi protein alpha subunits during ischemia-reperfusion in rats]. Wang Y, etal., Sheng Li Xue Bao. 1998 Oct;50(5):514-8.
Additional References at PubMed
PMID:1302014   PMID:2508088   PMID:2902634   PMID:7656338   PMID:8192889   PMID:8288218   PMID:8858601   PMID:9611134   PMID:10349636   PMID:10922068   PMID:10926822   PMID:11042159  
PMID:11073886   PMID:11076861   PMID:11158953   PMID:11248120   PMID:11342430   PMID:11544199   PMID:11771389   PMID:12297509   PMID:12477932   PMID:12520002   PMID:12904583   PMID:14610273  
PMID:15102471   PMID:15489334   PMID:15747579   PMID:15782199   PMID:15788486   PMID:16009138   PMID:16107646   PMID:16141072   PMID:16141073   PMID:16602821   PMID:16962188   PMID:17289675  
PMID:17296938   PMID:17360531   PMID:17418106   PMID:17484771   PMID:18156202   PMID:18378571   PMID:18501427   PMID:18521956   PMID:18832081   PMID:19401591   PMID:20508603   PMID:20607800  
PMID:21677750   PMID:21788441   PMID:21873635   PMID:21931697   PMID:21966394   PMID:22706085   PMID:22794259   PMID:23225882   PMID:23236180   PMID:23708969   PMID:23934215   PMID:23977324  
PMID:24098784   PMID:24135232   PMID:24312373   PMID:24478091   PMID:24639496   PMID:24751948   PMID:24858945   PMID:25016959   PMID:25044020   PMID:25225330   PMID:25242222   PMID:25565927  
PMID:25605782   PMID:25825741   PMID:25859222   PMID:25944935   PMID:26035863   PMID:26232433   PMID:26373672   PMID:26391662   PMID:26754646   PMID:26755700   PMID:26976957   PMID:27034005  
PMID:27317810   PMID:28346477   PMID:28378742   PMID:28387217   PMID:28484278   PMID:28646160   PMID:29229865   PMID:29342363   PMID:29507199   PMID:30100984   PMID:30196744   PMID:30233409  
PMID:30431055   PMID:30683698   PMID:30814219   PMID:30827920   PMID:30836096   PMID:30975754   PMID:31321879   PMID:32325033   PMID:32332099   PMID:32501280   PMID:32805026   PMID:32907846  
PMID:33754034   PMID:34001891   PMID:34253772   PMID:36260679   PMID:36808153   PMID:37153740   PMID:37843590  


Genomics

Comparative Map Data
Gnai3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393108,014,591 - 108,053,468 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl3108,014,596 - 108,053,462 (-)EnsemblGRCm39 Ensembl
GRCm383108,107,275 - 108,146,152 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3108,107,280 - 108,146,146 (-)EnsemblGRCm38mm10GRCm38
MGSCv373107,910,217 - 107,949,032 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv363108,235,355 - 108,274,170 (-)NCBIMGSCv36mm8
Celera3110,441,104 - 110,479,940 (-)NCBICelera
Cytogenetic Map3F2.3NCBI
cM Map346.83NCBI
GNAI3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381109,548,615 - 109,600,195 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1109,548,615 - 109,600,195 (+)EnsemblGRCh38hg38GRCh38
GRCh371110,091,237 - 110,142,817 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361109,892,824 - 109,938,498 (+)NCBINCBI36Build 36hg18NCBI36
Build 341109,803,342 - 109,849,017NCBI
Celera1108,360,485 - 108,407,751 (+)NCBICelera
Cytogenetic Map1p13.3NCBI
HuRef1107,983,708 - 108,030,976 (+)NCBIHuRef
CHM1_11110,206,106 - 110,253,386 (+)NCBICHM1_1
T2T-CHM13v2.01109,581,338 - 109,632,911 (+)NCBIT2T-CHM13v2.0
Gnai3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr82198,430,920 - 198,468,874 (-)NCBIGRCr8
mRatBN7.22195,742,765 - 195,780,720 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl2195,742,642 - 195,780,742 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx2203,385,968 - 203,423,940 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.02201,268,088 - 201,306,060 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.02196,085,045 - 196,123,015 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.02210,896,779 - 210,934,733 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2210,896,656 - 210,934,749 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02230,366,027 - 230,403,981 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42203,668,275 - 203,706,229 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.12203,631,028 - 203,668,983 (-)NCBI
Celera2188,388,024 - 188,425,978 (-)NCBICelera
RH 3.4 Map21390.8RGD
Cytogenetic Map2q34NCBI
Gnai3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543512,965,006 - 13,005,614 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495543512,965,006 - 13,005,614 (+)NCBIChiLan1.0ChiLan1.0
GNAI3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21117,710,945 - 117,755,897 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11116,870,871 - 116,915,787 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01111,925,668 - 111,971,941 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11111,154,060 - 111,198,771 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1111,154,060 - 111,198,768 (+)Ensemblpanpan1.1panPan2
GNAI3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1642,275,060 - 42,315,545 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl642,276,998 - 42,315,533 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha645,050,635 - 45,090,449 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0642,606,591 - 42,646,183 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl642,605,654 - 42,646,132 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1642,339,208 - 42,379,010 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0642,297,245 - 42,336,814 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0642,732,429 - 42,771,713 (-)NCBIUU_Cfam_GSD_1.0
Gnai3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505819,038,470 - 19,085,429 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367041,032,708 - 1,074,384 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367041,031,476 - 1,075,662 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GNAI3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl4110,525,546 - 110,579,053 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.14110,527,363 - 110,579,331 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.24120,990,186 - 121,037,989 (-)NCBISscrofa10.2Sscrofa10.2susScr3
GNAI3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12023,950,819 - 24,000,069 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2023,954,384 - 23,999,072 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603834,461,205 - 34,509,046 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Gnai3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247725,272,086 - 5,309,834 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Gnai3
1346 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:562
Count of miRNA genes:372
Interacting mature miRNAs:422
Transcripts:ENSMUST00000000001
Prediction methods:Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
26884436Zlq3_mzygomatic length QTL 3, 10 week (mouse)33265060142405761Mouse
26884427Cvht4_mcranial vault height 4, 10 week (mouse)316054164109707316Mouse
13207570Tcq12_mtotal cholesterol QTL 12 (mouse)316504164130163649Mouse
26884422Cvht7_mcranial vault height 7, 16 week (mouse)328954149118893649Mouse
1302056Orgwq4_morgan weight QTL 4 (mouse)Not determined330067588147304689Mouse
1301705Sles3_msystemic lupus erythmatosus suppressor 3 (mouse)Not determined337174862143353183Mouse
13208566Bmiq5_mbody mass index QTL 5 (mouse)340954435115793649Mouse
26884382Bzwq1_mbi-zygomatic width QTL 1, 5 week (mouse)352207421137205761Mouse
25314313Syncl1_msynaptonemal complex length 1 (mouse)367907333128393649Mouse
1300595Tmevd2_mTheiler's murine encephalomyelitis virus induced demyelinating disease susceptibility 2 (mouse)Not determined375463302109463549Mouse
1301392Eae3_msusceptibility to experimental allergic encephalomyelitis 3 (mouse)Not determined379548730113548837Mouse
1301947Pcfm3_mperiosteal circumference and femur length 3 (mouse)Not determined381084652115084797Mouse
1301904Iba2_minduction of brown adipocytes 2 (mouse)Not determined382147043116147184Mouse
11041900Lmr11a_mleishmaniasis resistance 11a (mouse)383463991117464137Mouse
11039510Ltpr3d_mLeishmania tropica response 3d (mouse)383463991117464137Mouse
11039511Ltpr3c_mLeishmania tropica response 3c (mouse)383463991117464137Mouse
11039507Ltpr3g_mLeishmania tropica response 3g (mouse)383463991117464137Mouse
11039508Ltpr3f_mLeishmania tropica response 3f (mouse)383463991117464137Mouse
11039509Ltpr3e_mLeishmania tropica response 3e (mouse)383463991117464137Mouse
11039512Ltpr3b_mLeishmania tropica response 3b (mouse)383463991117464137Mouse
1301272Cfsw1_mcystic fibrosis survival to weaning 1 (mouse)Not determined383882912117883044Mouse
4142099Cq3_mcholesterol QTL 3 (mouse)Not determined384888918118889067Mouse
14746984Manh54_mmandible shape 54 (mouse)385289152119289152Mouse
1357583Sle18_msystematic lupus erythematosus susceptibility 18 (mouse)Not determined387208904125316236Mouse
12738440Twq3_mtestis weight QTL 3 (mouse)387228015121228015Mouse
4142178Ctrq2_mC. trachomatis resistance QTL 2 (mouse)Not determined389139967137453008Mouse
10766455Sle22_msystematic lupus erythematosus susceptibility 22 (mouse)390376936124377072Mouse
14747001Mancz4_mmandible centroid size 4 (mouse)390378017124378017Mouse
1302052Etohcta4_methanol conditioned taste aversion 4 (mouse)Not determined391000105125008748Mouse
1301349Pgia26_mproteoglycan induced arthritis 26 (mouse)Not determined392251533126251650Mouse
27226732Tibmd3_mtibia midshaft diameter 3, 10 week (mouse)396607316147805636Mouse
10043955Wt10q4_mbody weight, 10 weeks, QTL 4 (mouse)Not determined398624041132624197Mouse
11533920Mvb3_mmodifier of vibrator 3 (mouse)398635284132635383Mouse
12792984Modn1_mmodifier of Dstn neovascularization 1 (mouse)398635284132635383Mouse
1302114Tbs1_mtuberculosis severity 1 (mouse)Not determined398924105132924250Mouse
1300752Ap6q_malcohol preference 6 QTL (mouse)Not determined3100372912147045722Mouse
26884419Bzwq6_mbi-zygomatic width QTL 6, 10 week (mouse)3100607316137205761Mouse
27226733Tibmd6_mtibia midshaft diameter 6, 16 week (mouse)3101307316149805637Mouse
1301805Mors2_mmodifier of obesity related sterility 2 (mouse)Not determined3103482659137482783Mouse
1357599msrvh1_mmodifier of susceptibility to renal vascular hypertrophy/hyperplasia 1 (mouse)Not determined3107376936115624197Mouse
8655599Cia5c_mcollagen induced arthritis QTL 5c (mouse)Not determined3107376936125316237Mouse
1302093Orgwq5_morgan weight QTL 5 (mouse)Not determined3107376936147304689Mouse

Markers in Region
AW537698  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383108,107,779 - 108,107,862UniSTSGRCm38
MGSCv373107,910,697 - 107,910,780UniSTSGRCm37
Celera3110,441,584 - 110,441,667UniSTS
Cytogenetic Map3F2.3UniSTS
Whitehead/MRC_RH31264.79UniSTS
Gnai3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map3F2.3UniSTS
cM Map348.8UniSTS
AI158965  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383108,107,697 - 108,107,861UniSTSGRCm38
MGSCv373107,910,615 - 107,910,779UniSTSGRCm37
Celera3110,441,502 - 110,441,666UniSTS
Cytogenetic Map3F2.3UniSTS
Whitehead/MRC_RH31173.82UniSTS
UniSTS:234799  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383108,107,412 - 108,107,613UniSTSGRCm38
MGSCv373107,910,330 - 107,910,531UniSTSGRCm37
Celera3110,441,217 - 110,441,418UniSTS
Cytogenetic Map3F2.3UniSTS
RH94416  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm383108,109,117 - 108,109,309UniSTSGRCm38
MGSCv373107,912,035 - 107,912,227UniSTSGRCm37
Celera3110,442,922 - 110,443,114UniSTS
Cytogenetic Map3F2.3UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010306 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK004566 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK077490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK133749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK167438 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK168578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK169285 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK187104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL671854 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC003462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC041107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP765831 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY126665 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  OU667058 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S79610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U38502 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000000001   ⟹   ENSMUSP00000000001
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl3108,014,596 - 108,053,462 (-)Ensembl
GRCm38.p6 Ensembl3108,107,280 - 108,146,146 (-)Ensembl
RefSeq Acc Id: NM_010306   ⟹   NP_034436
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm393108,014,591 - 108,053,468 (-)NCBI
GRCm383108,107,275 - 108,146,152 (-)NCBI
MGSCv373107,910,217 - 107,949,032 (-)RGD
Celera3110,441,080 - 110,479,978 (-)NCBI
cM Map3 ENTREZGENE
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_034436   ⟸   NM_010306
- UniProtKB: Q3TGV1 (UniProtKB/Swiss-Prot),   A2AE36 (UniProtKB/Swiss-Prot),   Q61019 (UniProtKB/Swiss-Prot),   Q9DC51 (UniProtKB/Swiss-Prot),   Q3TJH1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000000001   ⟸   ENSMUST00000000001
Protein Domains
G-alpha

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9DC51-F1-model_v2 AlphaFold Q9DC51 1-354 view protein structure

Promoters
RGD ID:6833899
Promoter ID:MM_KWN:35758
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000016610
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv363107,948,591 - 107,949,142 (-)MPROMDB
RGD ID:6882054
Promoter ID:EPDNEW_M4478
Type:initiation region
Name:Gnai3_1
Description:Mus musculus guanine nucleotide binding protein , alpha inhibiting3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm383108,146,089 - 108,146,149EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95773 AgrOrtholog
Ensembl Genes ENSMUSG00000000001 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000000001 ENTREZGENE
  ENSMUST00000000001.5 UniProtKB/Swiss-Prot
Gene3D-CATH 1.10.400.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  3.40.50.300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Gprotein_alpha_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Gprotein_alpha_su UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GproteinA_insert UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14679 UniProtKB/Swiss-Prot
MGD MGI:95773 ENTREZGENE
NCBI Gene 14679 ENTREZGENE
PANTHER GUANINE NUCLEOTIDE-BINDING PROTEIN G(I) SUBUNIT ALPHA-3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR10218 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam G-alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gnai3 PhenoGen
PRINTS GPROTEINA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPROTEINAI UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_ALPHA UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART G_alpha UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF47895 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF52540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AE36 ENTREZGENE
  GNAI3_MOUSE UniProtKB/Swiss-Prot
  Q3TGV1 ENTREZGENE
  Q3TJH1 ENTREZGENE, UniProtKB/TrEMBL
  Q61019 ENTREZGENE
  Q9DC51 ENTREZGENE
UniProt Secondary A2AE36 UniProtKB/Swiss-Prot
  Q3TGV1 UniProtKB/Swiss-Prot
  Q61019 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Gnai3  G protein subunit alpha i3  Gnai3  guanine nucleotide binding protein (G protein), alpha inhibiting 3  Symbol and/or name change 5135510 APPROVED