Gene: GNAI3 (guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3)  Homo sapiens

Symbol: GNAI3
Name: guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3
Description: Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling pathways. G proteins are composed of 3 units: alpha, beta and gamma. This gene encodes an alpha subunit and belongs to the G-alpha family. Mutation in this gene, resulting in a gly40-to-arg substitution, is associated with auriculocondylar syndrome, and shown to affect downstream targets in the G protein-coupled endothelin receptor pathway. [provided by RefSeq, Jun 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 87U6; ARCND1; FLJ26559; g(i) alpha-3; guanine nucleotide-binding protein G(k) subunit alpha; OTTHUMP00000013368
Orthologs: Mus musculus : Gnai3 (guanine nucleotide binding protein (G protein), alpha inhibiting 3)  MGI
Rattus norvegicus : Gnai3 (guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_11110,163,839 - 110,211,116+NCBI
Human Genome Assembly HuRef1107,983,708 - 108,030,976+NCBI
Human Genome Assembly GRCh371110,091,186 - 110,138,465+NCBI
Human Genome Assembly Build 361109,892,824 - 109,938,498+NCBI
Human Cytogenetic Map1p13 NCBI
Human Genome Assembly1109,803,342 - 109,849,017 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on GNAI3
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 731003
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2013-02-27
Status: ACTIVE