GRIK5 (glutamate ionotropic receptor kainate type subunit 5) - Rat Genome Database

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Gene: GRIK5 (glutamate ionotropic receptor kainate type subunit 5) Homo sapiens
Analyze
Symbol: GRIK5
Name: glutamate ionotropic receptor kainate type subunit 5
RGD ID: 730907
HGNC Page HGNC:4583
Description: Enables kainate selective glutamate receptor activity and ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential. Predicted to be involved in several processes, including glutamatergic synaptic transmission; protein retention in ER lumen; and receptor clustering. Predicted to act upstream of or within excitatory postsynaptic potential; monoatomic ion transmembrane transport; and regulation of synaptic vesicle fusion to presynaptic active zone membrane. Located in nucleoplasm and plasma membrane. Implicated in chronic obstructive pulmonary disease. Biomarker of temporal lobe epilepsy.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: EAA2; excitatory amino acid receptor 2; GluK5; glutamate receptor ionotropic, kainate 5; glutamate receptor KA-2; glutamate receptor KA2; glutamate receptor, ionotropic kainate 5; glutamate receptor, ionotropic, kainate 5; GRIK2; KA2; putative NMDtranscript(altDon_e2); putative NMDtranscript(del_e13-e15)
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,998,324 - 42,070,206 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1941,998,321 - 42,070,206 (-)EnsemblGRCh38hg38GRCh38
GRCh371942,502,476 - 42,574,358 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,194,313 - 47,261,797 (-)NCBINCBI36Build 36hg18NCBI36
Build 341947,194,312 - 47,261,797NCBI
Celera1939,302,092 - 39,369,575 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1938,934,282 - 39,001,175 (-)NCBIHuRef
CHM1_11942,504,085 - 42,571,606 (-)NCBICHM1_1
T2T-CHM13v2.01944,817,686 - 44,889,570 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
2. Functional cooperation between KA2 and GluR6 subunits is involved in the ischemic brain injury. Jiang HX, etal., J Neurosci Res. 2007 Oct;85(13):2960-70.
3. [Polymorphic Variants of Glutamate Receptor (GRIK5, GRIN2B) and Serotonin Receptor (HTR2A) Genes Are Associated with Chronic Obstructive Pulmonary Disease]. Korytina GF, etal., Mol Biol (Mosk). 2017 Jul-Aug;51(4):603-614. doi: 10.7868/S0026898417040127.
4. Altered hippocampal kainate-receptor mRNA levels in temporal lobe epilepsy patients. Mathern GW, etal., Neurobiol Dis. 1998 Sep;5(3):151-76.
5. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Allelic association of juvenile absence epilepsy with a GluR5 kainate receptor gene (GRIK1) polymorphism. Sander T, etal., Am J Med Genet 1997 Jul 25;74(4):416-21.
9. Antagonists of GLU(K5)-containing kainate receptors prevent pilocarpine-induced limbic seizures. Smolders I, etal., Nat Neurosci 2002 Aug;5(8):796-804.
10. The genes encoding the glutamate receptor subunits KA1 and KA2 (GRIK4 and GRIK5) are located on separate chromosomes in human, mouse, and rat. Szpirer C, etal., Proc Natl Acad Sci U S A 1994 Dec 6;91(25):11849-53.
11. Kainate-induced seizures alter protein composition and N-methyl-D-aspartate receptor function of rat forebrain postsynaptic densities. Wyneken U, etal., Neuroscience. 2001;102(1):65-74.
Additional References at PubMed
PMID:1321949   PMID:8288598   PMID:9039653   PMID:9099808   PMID:9466455   PMID:9808460   PMID:11279111   PMID:12477932   PMID:12573530   PMID:14511640   PMID:15254951   PMID:15583001  
PMID:16169070   PMID:16325263   PMID:18247129   PMID:18562611   PMID:19086053   PMID:19125103   PMID:19342380   PMID:20026616   PMID:21771265   PMID:21873635   PMID:23288040   PMID:28319085  
PMID:29058671   PMID:29676528   PMID:29955894   PMID:30339823   PMID:30827500   PMID:33961781   PMID:34100982   PMID:35256949   PMID:36959746  


Genomics

Comparative Map Data
GRIK5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381941,998,324 - 42,070,206 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1941,998,321 - 42,070,206 (-)EnsemblGRCh38hg38GRCh38
GRCh371942,502,476 - 42,574,358 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361947,194,313 - 47,261,797 (-)NCBINCBI36Build 36hg18NCBI36
Build 341947,194,312 - 47,261,797NCBI
Celera1939,302,092 - 39,369,575 (-)NCBICelera
Cytogenetic Map19q13.2NCBI
HuRef1938,934,282 - 39,001,175 (-)NCBIHuRef
CHM1_11942,504,085 - 42,571,606 (-)NCBICHM1_1
T2T-CHM13v2.01944,817,686 - 44,889,570 (-)NCBIT2T-CHM13v2.0
Grik5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39724,709,274 - 24,775,421 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl724,709,274 - 24,771,771 (-)EnsemblGRCm39 Ensembl
GRCm38725,009,849 - 25,075,694 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl725,009,849 - 25,072,346 (-)EnsemblGRCm38mm10GRCm38
MGSCv37725,794,868 - 25,857,388 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36724,718,636 - 24,781,058 (-)NCBIMGSCv36mm8
Celera719,625,658 - 19,688,340 (-)NCBICelera
Cytogenetic Map7A3NCBI
cM Map713.73NCBI
Grik5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8189,733,736 - 89,795,769 (-)NCBIGRCr8
mRatBN7.2180,605,878 - 80,667,896 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl180,605,892 - 80,667,125 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx185,998,459 - 86,059,573 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0194,549,318 - 94,610,432 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0187,754,221 - 87,815,339 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0181,885,516 - 81,946,731 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl181,885,521 - 81,946,714 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0183,137,805 - 83,207,039 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4180,313,801 - 80,384,390 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1180,391,911 - 80,462,398 (-)NCBI
Celera175,051,832 - 75,112,171 (-)NCBICelera
Cytogenetic Map1q21NCBI
Grik5
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955555812,928 - 864,874 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955555804,907 - 865,395 (+)NCBIChiLan1.0ChiLan1.0
GRIK5
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22048,103,370 - 48,174,201 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11949,971,984 - 50,042,814 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01938,886,108 - 38,956,938 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11947,389,253 - 47,549,018 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1947,389,804 - 47,544,604 (-)Ensemblpanpan1.1panPan2
GRIK5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11112,270,157 - 112,321,672 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1112,270,424 - 112,321,672 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1111,702,486 - 111,753,731 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01112,887,140 - 112,941,269 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1112,889,737 - 112,941,269 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11112,443,154 - 112,494,596 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01112,079,617 - 112,130,847 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01113,005,888 - 113,057,155 (+)NCBIUU_Cfam_GSD_1.0
Grik5
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934916,062,693 - 16,121,657 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936706410,938 - 464,714 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936706410,806 - 469,000 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
GRIK5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl649,845,656 - 49,902,080 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1649,840,671 - 49,901,656 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2645,891,687 - 45,922,679 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GRIK5
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1636,199,358 - 36,273,355 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl636,199,349 - 36,269,591 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607314,441,791 - 14,521,580 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Grik5
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624907653,895 - 710,791 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624907653,568 - 711,358 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in GRIK5
37 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 19q13.12-13.2(chr19:37319377-42738688)x3 copy number gain See cases [RCV000050636] Chr19:37319377..42738688 [GRCh38]
Chr19:37810279..43242840 [GRCh37]
Chr19:42502119..47934680 [NCBI36]
Chr19:19q13.12-13.2
pathogenic
GRCh38/hg38 19q13.2-13.31(chr19:41930894-43141456)x1 copy number loss See cases [RCV000053975] Chr19:41930894..43141456 [GRCh38]
Chr19:42514712..43645608 [GRCh37]
Chr19:47126886..48337448 [NCBI36]
Chr19:19q13.2-13.31
pathogenic
NM_002088.4(GRIK5):c.475C>T (p.Pro159Ser) single nucleotide variant Malignant melanoma [RCV000072172] Chr19:42062521 [GRCh38]
Chr19:42566673 [GRCh37]
Chr19:47258513 [NCBI36]
Chr19:19q13.2
not provided
NM_002088.4(GRIK5):c.452G>A (p.Arg151Gln) single nucleotide variant Malignant melanoma [RCV000072173] Chr19:42062544 [GRCh38]
Chr19:42566696 [GRCh37]
Chr19:47258536 [NCBI36]
Chr19:19q13.2
not provided
GRCh38/hg38 19p13.2-q13.31(chr19:11227942-44626354)x3 copy number gain See cases [RCV000133888] Chr19:11227942..44626354 [GRCh38]
Chr19:11338618..45129651 [GRCh37]
Chr19:11199618..49821491 [NCBI36]
Chr19:19p13.2-q13.31
pathogenic
GRCh37/hg19 19q13.2(chr19:42384461-42504505)x3 copy number gain not provided [RCV000752690] Chr19:42384461..42504505 [GRCh37]
Chr19:19q13.2
benign
GRCh37/hg19 19q13.2(chr19:42542999-42553864)x1 copy number loss not provided [RCV000752691] Chr19:42542999..42553864 [GRCh37]
Chr19:19q13.2
benign
GRCh37/hg19 19q13.2(chr19:42547911-42553864)x1 copy number loss not provided [RCV000752692] Chr19:42547911..42553864 [GRCh37]
Chr19:19q13.2
benign
NM_002088.4(GRIK5):c.1698-4A>T single nucleotide variant not specified [RCV000438749] Chr19:42021478 [GRCh38]
Chr19:42525630 [GRCh37]
Chr19:19q13.2
likely benign
GRCh37/hg19 19q13.2(chr19:42380680-42738966)x3 copy number gain See cases [RCV000448991] Chr19:42380680..42738966 [GRCh37]
Chr19:19q13.2
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888)x3 copy number gain See cases [RCV000511289] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic|uncertain significance
NM_002088.5(GRIK5):c.1376G>A (p.Arg459His) single nucleotide variant Inborn genetic diseases [RCV003246074] Chr19:42042649 [GRCh38]
Chr19:42546801 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.1393C>T (p.Arg465Trp) single nucleotide variant Inborn genetic diseases [RCV003253472] Chr19:42042632 [GRCh38]
Chr19:42546784 [GRCh37]
Chr19:19q13.2
uncertain significance
GRCh37/hg19 19p13.3-q13.43(chr19:260912-58956888) copy number gain See cases [RCV000512296] Chr19:260912..58956888 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19q13.2(chr19:42553198-42580706)x1 copy number loss not provided [RCV000752693] Chr19:42553198..42580706 [GRCh37]
Chr19:19q13.2
benign
GRCh37/hg19 19p13.3-q13.43(chr19:68029-59110290)x3 copy number gain not provided [RCV000752439] Chr19:68029..59110290 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
GRCh37/hg19 19p13.3-q13.43(chr19:260912-59097160)x3 copy number gain not provided [RCV000752444] Chr19:260912..59097160 [GRCh37]
Chr19:19p13.3-q13.43
pathogenic
Single allele duplication Schizophrenia [RCV000754211] Chr19:41608672..44315856 [GRCh38]
Chr19:19q13.2-13.31
likely pathogenic
NM_002088.5(GRIK5):c.1167G>A (p.Gly389=) single nucleotide variant not provided [RCV000882411] Chr19:42053704 [GRCh38]
Chr19:42557856 [GRCh37]
Chr19:19q13.2
likely benign
GRCh37/hg19 19q11-13.33(chr19:28271106-49213832)x3 copy number gain not provided [RCV000845733] Chr19:28271106..49213832 [GRCh37]
Chr19:19q11-13.33
pathogenic
NC_000019.9:g.(?_39904727)_(42931301_?)dup duplication Diamond-Blackfan anemia [RCV003122291]|MEGF8-related Carpenter syndrome [RCV003105286]|Maple syrup urine disease [RCV003105287]|TWIST1-related craniosynostosis [RCV003105285] Chr19:39904727..42931301 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2076C>T (p.Tyr692=) single nucleotide variant not provided [RCV000955559] Chr19:42005910 [GRCh38]
Chr19:42510062 [GRCh37]
Chr19:19q13.2
benign
NM_002088.5(GRIK5):c.2495G>T (p.Arg832Met) single nucleotide variant not provided [RCV000959791] Chr19:42003351 [GRCh38]
Chr19:42507503 [GRCh37]
Chr19:19q13.2
benign
NC_000019.10:g.41983952_42247520del deletion Syndromic intellectual disability [RCV001374687] Chr19:41983952..42247520 [GRCh38]
Chr19:19q13.2
pathogenic
NC_000019.10:g.41952441_42266625del deletion Syndromic craniosynostosis [RCV001374686] Chr19:41952441..42266625 [GRCh38]
Chr19:19q13.2
pathogenic
NC_000019.10:g.42032860_42297536del deletion Syndromic craniosynostosis [RCV001374689] Chr19:42032860..42297536 [GRCh38]
Chr19:19q13.2
pathogenic
GRCh38/hg38 19q13.2(chr19:41987984-42252574)x1 copy number loss Syndromic intellectual disability [RCV001374690] Chr19:41987984..42252574 [GRCh38]
Chr19:19q13.2
pathogenic
NM_002088.5(GRIK5):c.1162A>G (p.Ile388Val) single nucleotide variant Inborn genetic diseases [RCV003258350] Chr19:42053709 [GRCh38]
Chr19:42557861 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2353G>C (p.Gly785Arg) single nucleotide variant Inborn genetic diseases [RCV002733844] Chr19:42003594 [GRCh38]
Chr19:42507746 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.692C>T (p.Ser231Leu) single nucleotide variant Inborn genetic diseases [RCV002688050] Chr19:42056974 [GRCh38]
Chr19:42561126 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.160A>G (p.Ile54Val) single nucleotide variant Inborn genetic diseases [RCV002860950] Chr19:42065307 [GRCh38]
Chr19:42569459 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.205G>C (p.Glu69Gln) single nucleotide variant Inborn genetic diseases [RCV002906541] Chr19:42065262 [GRCh38]
Chr19:42569414 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.433G>A (p.Val145Ile) single nucleotide variant Inborn genetic diseases [RCV002753895] Chr19:42062563 [GRCh38]
Chr19:42566715 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.401C>T (p.Ala134Val) single nucleotide variant Inborn genetic diseases [RCV002762384] Chr19:42062595 [GRCh38]
Chr19:42566747 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.236C>T (p.Thr79Met) single nucleotide variant Inborn genetic diseases [RCV002782532] Chr19:42065231 [GRCh38]
Chr19:42569383 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.1394G>A (p.Arg465Gln) single nucleotide variant Inborn genetic diseases [RCV002910544] Chr19:42042631 [GRCh38]
Chr19:42546783 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2240G>A (p.Gly747Asp) single nucleotide variant Inborn genetic diseases [RCV002976750] Chr19:42005746 [GRCh38]
Chr19:42509898 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.620G>A (p.Arg207His) single nucleotide variant Inborn genetic diseases [RCV002925424] Chr19:42059416 [GRCh38]
Chr19:42563568 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2777C>A (p.Pro926His) single nucleotide variant Inborn genetic diseases [RCV002987063] Chr19:41999037 [GRCh38]
Chr19:42503189 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2825T>G (p.Leu942Arg) single nucleotide variant Inborn genetic diseases [RCV002803223] Chr19:41998989 [GRCh38]
Chr19:42503141 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.400G>A (p.Ala134Thr) single nucleotide variant Inborn genetic diseases [RCV002984270] Chr19:42062596 [GRCh38]
Chr19:42566748 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2296A>G (p.Ile766Val) single nucleotide variant Inborn genetic diseases [RCV002983200] Chr19:42003651 [GRCh38]
Chr19:42507803 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.229G>A (p.Glu77Lys) single nucleotide variant Inborn genetic diseases [RCV002712571] Chr19:42065238 [GRCh38]
Chr19:42569390 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2816T>G (p.Ile939Ser) single nucleotide variant Inborn genetic diseases [RCV002803222] Chr19:41998998 [GRCh38]
Chr19:42503150 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.1837C>G (p.Arg613Gly) single nucleotide variant Inborn genetic diseases [RCV002897762] Chr19:42021335 [GRCh38]
Chr19:42525487 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2830G>A (p.Ala944Thr) single nucleotide variant Inborn genetic diseases [RCV002940834] Chr19:41998984 [GRCh38]
Chr19:42503136 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.113G>A (p.Arg38His) single nucleotide variant Inborn genetic diseases [RCV002987995] Chr19:42065354 [GRCh38]
Chr19:42569506 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.259C>G (p.Pro87Ala) single nucleotide variant Inborn genetic diseases [RCV002878645] Chr19:42062841 [GRCh38]
Chr19:42566993 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.246G>C (p.Met82Ile) single nucleotide variant Inborn genetic diseases [RCV002723348] Chr19:42062854 [GRCh38]
Chr19:42567006 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.376C>A (p.Pro126Thr) single nucleotide variant Inborn genetic diseases [RCV003213221] Chr19:42062620 [GRCh38]
Chr19:42566772 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.1220A>G (p.Asn407Ser) single nucleotide variant Inborn genetic diseases [RCV003173563] Chr19:42053651 [GRCh38]
Chr19:42557803 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2565C>G (p.Cys855Trp) single nucleotide variant Inborn genetic diseases [RCV003219899] Chr19:41999249 [GRCh38]
Chr19:42503401 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.590G>A (p.Arg197Gln) single nucleotide variant Inborn genetic diseases [RCV003265522] Chr19:42059446 [GRCh38]
Chr19:42563598 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.965A>G (p.Asn322Ser) single nucleotide variant Inborn genetic diseases [RCV003357463] Chr19:42054411 [GRCh38]
Chr19:42558563 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2134G>A (p.Val712Ile) single nucleotide variant Inborn genetic diseases [RCV003343318] Chr19:42005852 [GRCh38]
Chr19:42510004 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.115G>A (p.Gly39Ser) single nucleotide variant Inborn genetic diseases [RCV003345462] Chr19:42065352 [GRCh38]
Chr19:42569504 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2588G>C (p.Arg863Pro) single nucleotide variant Inborn genetic diseases [RCV003366846] Chr19:41999226 [GRCh38]
Chr19:42503378 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.1744C>T (p.Arg582Cys) single nucleotide variant Inborn genetic diseases [RCV003354076] Chr19:42021428 [GRCh38]
Chr19:42525580 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2521G>C (p.Val841Leu) single nucleotide variant Inborn genetic diseases [RCV003372360] Chr19:41999293 [GRCh38]
Chr19:42503445 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2770C>T (p.Pro924Ser) single nucleotide variant Inborn genetic diseases [RCV003386652] Chr19:41999044 [GRCh38]
Chr19:42503196 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2359C>T (p.Arg787Trp) single nucleotide variant GRIK5-related condition [RCV003397548] Chr19:42003588 [GRCh38]
Chr19:42507740 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.432C>T (p.Asp144=) single nucleotide variant not provided [RCV003406991] Chr19:42062564 [GRCh38]
Chr19:42566716 [GRCh37]
Chr19:19q13.2
likely benign
NM_002088.5(GRIK5):c.1426G>A (p.Glu476Lys) single nucleotide variant GRIK5-related condition [RCV003408789] Chr19:42042599 [GRCh38]
Chr19:42546751 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.316G>T (p.Val106Leu) single nucleotide variant GRIK5-related condition [RCV003412216] Chr19:42062784 [GRCh38]
Chr19:42566936 [GRCh37]
Chr19:19q13.2
uncertain significance
NM_002088.5(GRIK5):c.2706G>T (p.Ala902=) single nucleotide variant not provided [RCV003415260] Chr19:41999108 [GRCh38]
Chr19:42503260 [GRCh37]
Chr19:19q13.2
likely benign
NM_002088.5(GRIK5):c.2514+908G>A single nucleotide variant not provided [RCV003425195] Chr19:42002424 [GRCh38]
Chr19:42506576 [GRCh37]
Chr19:19q13.2
likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2638
Count of miRNA genes:1007
Interacting mature miRNAs:1244
Transcripts:ENST00000262895, ENST00000301218, ENST00000454993, ENST00000593562, ENST00000594528, ENST00000602210
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
SHGC-148130  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371942,541,947 - 42,542,257UniSTSGRCh37
Build 361947,233,787 - 47,234,097RGDNCBI36
Celera1939,341,565 - 39,341,875RGD
Cytogenetic Map19q13.2UniSTS
HuRef1938,973,231 - 38,973,541UniSTS
TNG Radiation Hybrid Map1915827.0UniSTS
GRIK5_3042  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371942,502,281 - 42,502,897UniSTSGRCh37
Build 361947,194,121 - 47,194,737RGDNCBI36
Celera1939,301,900 - 39,302,516RGD
HuRef1938,934,095 - 38,934,711UniSTS
UniSTS:496047  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371942,509,982 - 42,510,085UniSTSGRCh37
Build 361947,201,822 - 47,201,925RGDNCBI36
Celera1939,309,602 - 39,309,705RGD
HuRef1938,941,797 - 38,941,900UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component
High
Medium 1520 1197 969 2 61 2 1004 866 2696 84 789 717 7 816
Low 765 1119 231 217 739 72 2600 686 976 200 572 680 150 1077 1408
Below cutoff 134 660 489 369 1043 356 738 641 36 118 81 203 19 120 564 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001301030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002088 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005258821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526865 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011526871 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017026713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438705 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047438706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320745 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320746 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320747 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320748 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320750 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054320751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_008485135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_935810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC010616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC020946 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC022515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ249209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC037358 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC052975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC131717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BK014581 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BK014582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM152516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA432656 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471126 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068259 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KC877730 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S40369 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000262895   ⟹   ENSP00000262895
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,998,321 - 42,065,770 (-)Ensembl
RefSeq Acc Id: ENST00000301218   ⟹   ENSP00000301218
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1942,001,786 - 42,065,805 (-)Ensembl
RefSeq Acc Id: ENST00000454993
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,998,321 - 42,042,901 (-)Ensembl
RefSeq Acc Id: ENST00000593562   ⟹   ENSP00000470251
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,998,324 - 42,070,206 (-)Ensembl
RefSeq Acc Id: ENST00000594528   ⟹   ENSP00000469135
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1942,021,331 - 42,065,805 (-)Ensembl
RefSeq Acc Id: ENST00000602210
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1941,999,243 - 42,003,764 (-)Ensembl
RefSeq Acc Id: NM_001301030   ⟹   NP_001287959
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,001,786 - 42,070,206 (-)NCBI
CHM1_11942,507,555 - 42,571,616 (-)NCBI
T2T-CHM13v2.01944,821,148 - 44,889,570 (-)NCBI
Sequence:
RefSeq Acc Id: NM_002088   ⟹   NP_002079
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381941,998,324 - 42,070,206 (-)NCBI
GRCh371942,502,468 - 42,574,278 (-)NCBI
Build 361947,194,313 - 47,261,797 (-)NCBI Archive
HuRef1938,934,282 - 39,001,175 (-)NCBI
CHM1_11942,504,085 - 42,571,606 (-)NCBI
T2T-CHM13v2.01944,817,686 - 44,889,570 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011526862   ⟹   XP_011525164
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381941,998,324 - 42,070,194 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011526865   ⟹   XP_011525167
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,001,786 - 42,070,194 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011526869   ⟹   XP_011525171
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,020,869 - 42,070,194 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011526870   ⟹   XP_011525172
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,038,120 - 42,070,194 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011526871   ⟹   XP_011525173
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,022,585 - 42,070,194 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047438705   ⟹   XP_047294661
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,001,786 - 42,065,309 (-)NCBI
RefSeq Acc Id: XM_047438706   ⟹   XP_047294662
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,020,869 - 42,070,194 (-)NCBI
RefSeq Acc Id: XM_054320745   ⟹   XP_054176720
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,821,148 - 44,889,558 (-)NCBI
RefSeq Acc Id: XM_054320746   ⟹   XP_054176721
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,817,686 - 44,889,558 (-)NCBI
RefSeq Acc Id: XM_054320747   ⟹   XP_054176722
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,821,148 - 44,884,673 (-)NCBI
RefSeq Acc Id: XM_054320748   ⟹   XP_054176723
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,834,270 - 44,889,558 (-)NCBI
RefSeq Acc Id: XM_054320749   ⟹   XP_054176724
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,834,271 - 44,889,558 (-)NCBI
RefSeq Acc Id: XM_054320750   ⟹   XP_054176725
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,856,911 - 44,889,558 (-)NCBI
RefSeq Acc Id: XM_054320751   ⟹   XP_054176726
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,841,949 - 44,889,558 (-)NCBI
RefSeq Acc Id: XR_008485135
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01944,825,287 - 44,889,558 (-)NCBI
RefSeq Acc Id: XR_935810
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,005,924 - 42,070,194 (-)NCBI
Sequence:
RefSeq Acc Id: NP_002079   ⟸   NM_002088
- Peptide Label: isoform 2 precursor
- UniProtKB: Q8WWG8 (UniProtKB/Swiss-Prot),   Q16478 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001287959   ⟸   NM_001301030
- Peptide Label: isoform 1 precursor
- UniProtKB: Q16478 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011525164   ⟸   XM_011526862
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011525167   ⟸   XM_011526865
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011525171   ⟸   XM_011526869
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_011525173   ⟸   XM_011526871
- Peptide Label: isoform X7
- UniProtKB: A0A8D9UIS7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011525172   ⟸   XM_011526870
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: ENSP00000469135   ⟸   ENST00000594528
RefSeq Acc Id: ENSP00000301218   ⟸   ENST00000301218
RefSeq Acc Id: ENSP00000262895   ⟸   ENST00000262895
RefSeq Acc Id: ENSP00000470251   ⟸   ENST00000593562
RefSeq Acc Id: XP_047294661   ⟸   XM_047438705
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047294662   ⟸   XM_047438706
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054176721   ⟸   XM_054320746
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054176720   ⟸   XM_054320745
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054176722   ⟸   XM_054320747
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054176723   ⟸   XM_054320748
- Peptide Label: isoform X4
RefSeq Acc Id: XP_054176724   ⟸   XM_054320749
- Peptide Label: isoform X5
RefSeq Acc Id: XP_054176726   ⟸   XM_054320751
- Peptide Label: isoform X7
- UniProtKB: A0A8D9UIS7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_054176725   ⟸   XM_054320750
- Peptide Label: isoform X6
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q16478-F1-model_v2 AlphaFold Q16478 1-980 view protein structure

Promoters
RGD ID:7240141
Promoter ID:EPDNEW_H25816
Type:initiation region
Name:GRIK5_2
Description:glutamate ionotropic receptor kainate type subunit 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25817  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,042,851 - 42,042,911EPDNEW
RGD ID:7240143
Promoter ID:EPDNEW_H25817
Type:initiation region
Name:GRIK5_1
Description:glutamate ionotropic receptor kainate type subunit 5
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H25816  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381942,065,784 - 42,065,844EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4583 AgrOrtholog
COSMIC GRIK5 COSMIC
Ensembl Genes ENSG00000105737 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000262895.7 UniProtKB/Swiss-Prot
  ENST00000301218 ENTREZGENE
  ENST00000301218.8 UniProtKB/Swiss-Prot
  ENST00000593562 ENTREZGENE
  ENST00000593562.6 UniProtKB/Swiss-Prot
  ENST00000594528.1 UniProtKB/TrEMBL
Gene3D-CATH 3.40.50.2300 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Periplasmic binding protein-like II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000105737 GTEx
HGNC ID HGNC:4583 ENTREZGENE
Human Proteome Map GRIK5 Human Proteome Map
InterPro ANF_lig-bd_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glu/Gly-bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Iono_rcpt_met UniProtKB/Swiss-Prot
  Ionotropic_Glu_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Iontro_rcpt UniProtKB/Swiss-Prot
  Peripla_BP_I UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:2901 UniProtKB/Swiss-Prot
NCBI Gene 2901 ENTREZGENE
OMIM 600283 OMIM
PANTHER GLUTAMATE RECEPTOR IONOTROPIC, KAINATE 5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  IONOTROPIC GLUTAMATE RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam ANF_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lig_chan UniProtKB/Swiss-Prot
  Lig_chan-Glu_bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB GRIK5 RGD, PharmGKB
PRINTS NMDARECEPTOR UniProtKB/Swiss-Prot
SMART Lig_chan-Glu_bd UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PBPe UniProtKB/Swiss-Prot
Superfamily-SCOP Periplasmic binding protein-like II UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF53822 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8D9UIS7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D9UJB7_HUMAN UniProtKB/TrEMBL
  GRIK5_HUMAN UniProtKB/Swiss-Prot
  M0QXF6_HUMAN UniProtKB/TrEMBL
  Q16478 ENTREZGENE
  Q8WWG8 ENTREZGENE
UniProt Secondary Q8WWG8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-10 GRIK5  glutamate ionotropic receptor kainate type subunit 5  GRIK5  glutamate receptor, ionotropic, kainate 5  Symbol and/or name change 5135510 APPROVED