NCOR1 (nuclear receptor corepressor 1)

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Keyword

Gene: NCOR1 (nuclear receptor corepressor 1) Homo sapiens

Symbol:

NCOR1

Name:

nuclear receptor corepressor 1

Description:

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

hCIT529I10; hN-CoR; KIAA1047; MGC104216; N-CoR; N-CoR1; nuclear receptor co-repressor 1; nuclear receptor corepressor 1; OTTHUMP00000065575; OTTHUMP00000065577; OTTHUMP00000065578; OTTHUMP00000065580; thyroid hormone- and retinoic acid receptor-associated corepressor 1; TRAC1

Orthologs:

Mus musculus : Ncor1 (nuclear receptor co-repressor 1) MGI
Rattus norvegicus : Ncor1 (nuclear receptor co-repressor 1)

Related Pseudogenes:

NCOR1P1 NCOR1P2 NCOR1P3

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	17	15,921,517 - 16,107,493	-	NCBI
Human Genome Assembly HuRef	17	15,800,450 - 15,985,911	-	NCBI
Human Genome Assembly GRCh37	17	15,933,408 - 16,118,874	-	NCBI
Human Genome Assembly Build 36	17	15,875,983 - 16,059,570	-	NCBI
Human Cytogenetic Map	17	p11.2		NCBI
Human Genome Assembly	17	15,875,983 - 16,059,570		NCBI