Gene: ANGPT2 (angiopoietin 2)  Homo sapiens

Symbol: ANGPT2
Name: angiopoietin 2
Description: The protein encoded by this gene is an antagonist of angiopoietin 1 (ANGPT1) and endothelial TEK tyrosine kinase (TIE-2, TEK). The encoded protein disrupts the vascular remodeling ability of ANGPT1 and may induce endothelial cell apoptosis. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGPT2; ANG-2; ANG2; angiopoietin-2; angiopoietin-2a; angiopoietin-2B; OTTHUMP00000115423; OTTHUMP00000224502; OTTHUMP00000224503; Tie2-ligand
Orthologs: Mus musculus : Angpt2 (angiopoietin 2)  MGI
Rattus norvegicus : Angpt2 (angiopoietin 2)
Latest Assembly: Human Genome Assembly GRCh37
Position:
MapChrPositionStrandSource
Human Alternate Assembly CHM1_186,563,240 - 6,626,689-NCBI
Human Genome Assembly HuRef86,139,162 - 6,202,785-NCBI
Human Genome Assembly GRCh3786,357,172 - 6,420,784-NCBI
Human Genome Assembly Build 3686,347,601 - 6,408,170-NCBI
Human Cytogenetic Map8p23.1 NCBI
Human Genome Assembly86,347,600 - 6,408,172 NCBI
Model

Launch Genome Browser (GBrowse) : build 36 (hg18) build 37 (hg19)


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Human Genome Assembly GRCh37)

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on ANGPT2
Entrez Gene
Ensembl Gene
Genome Browser: (hg18) (hg19)
HGNC Report
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 730844
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2013-06-04
Status: ACTIVE