Gene: F8 (coagulation factor VIII) Rattus norvegicus
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Symbol: F8
Name: coagulation factor VIII
Description: ENCODES a protein that exhibits copper ion binding (inferred); oxidoreductase activity (inferred); INVOLVED IN blood coagulation; blood coagulation, intrinsic pathway; PARTICIPATES IN coagulation cascade pathway; acenocoumarol pharmacodynamics pathway; alteplase pharmacodynamics pathway; ASSOCIATED WITH Endotoxemia; factor VIII deficiency; Hemophilia A; FOUND IN extracellular space; INTERACTS WITH 1,3-dinitrobenzene; 2,4-dinitrotoluene; 2,6-dinitrotoluene
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: coagulation factor VIII, procoagulant component
Orthologs:
Homo sapiens (human) : F8 (coagulation factor VIII)  HGNC  AGR
Mus musculus (house mouse) : F8 (coagulation factor VIII)  MGI  AGR
Chinchilla lanigera (long-tailed chinchilla) : F8 (coagulation factor VIII)
Pan paniscus (bonobo/pygmy chimpanzee) : F8 (coagulation factor VIII)
Canis lupus familiaris (dog) : F8 (coagulation factor VIII)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : F8 (coagulation factor VIII)
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Allele / Splice: F8m1Ycb   F8em1Sage  
Genetic Models: SD/Novo-F8em1Sage+/- SD/Novo-F8em1Sage SD/Novo-F8em1Sage-/- WAG-F8m1Ycb
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.018367,862 - 399,242 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.018413,447 - 444,491 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.418121,134 - 162,008 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.118121,133 - 162,008 (+)NCBI
Celera18135,235 - 166,779 (+)NCBICelera
Cytogenetic Map18p13NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
 
More on F8
AGR Gene
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 727845
Created: 2003-11-05
Species: Rattus norvegicus
Last Modified: 2017-09-05
Status: ACTIVE