Gene: Egln3 (EGL nine homolog 3 (C. elegans))  Rattus norvegicus

Symbol: Egln3
Name: EGL nine homolog 3 (C. elegans)
Description: ENCODES a protein that exhibits peptidyl-proline dioxygenase activity; peptidyl-proline 4-dioxygenase activity (ortholog); INVOLVED IN regulation of cell proliferation; response to hypoxia; activation of cysteine-type endopeptidase activity involved in apoptotic process (ortholog); PARTICIPATES IN hypoxia inducible factor pathway; vascular endothelial growth factor signaling pathway; renal cell cancer pathway; FOUND IN cytosol; cytoplasm (ortholog); nucleus (ortholog); INTERACTS WITH 1,2,4-trimethylbenzene; 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: egl nine homolog 3; egl nine homolog 3, mitochondrial; factor-responsive smooth muscle protein; HIF-PH3; HIF-prolyl hydroxylase 3; HPH-3; hypoxia-inducible factor prolyl hydroxylase 3; PHD-3; PHD3; prolyl hydroxylase domain-containing protein 3; SM-20
Orthologs: Homo sapiens : EGLN3 (egl nine homolog 3 (C. elegans))  HGNC
Mus musculus : Egln3 (EGL nine homolog 3 (C. elegans))  MGI
Allele / Splice: Egln3m1Mcwi  
Latest Assembly: RGSC Genome Assembly v3.4
Position:
MapChrPositionStrandSource
Rat Cytogenetic Map6q23 NCBI
RGSC Genome Assembly v5.0684,592,894 - 84,618,360-NCBI
RGSC Genome Assembly v3.4674,451,038 - 74,476,506-NCBI
Rat Celera Assembly670,500,466 - 70,525,910-NCBI
Genome Assembly 3.1674,454,165 - 74,479,632-NCBI
Model

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Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (RGSC Genome Assembly v3.4)

Sequence

Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Egln3
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RGD Object Information
RGD ID: 71019
Created: 2002-07-09
Species: Rattus norvegicus
Last Modified: 2013-04-16
Status: ACTIVE