Decr2 (2,4-dienoyl-CoA reductase 2) - Rat Genome Database

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Gene: Decr2 (2,4-dienoyl-CoA reductase 2) Rattus norvegicus
Analyze
Symbol: Decr2 (Ensembl: Rab11fip3)
Name: 2,4-dienoyl-CoA reductase 2 (Ensembl:RAB11 family interacting protein 3)
RGD ID: 71002
Description: Enables 2,4-dienoyl-CoA reductase (NADPH) activity. Predicted to be involved in unsaturated fatty acid biosynthetic process. Located in peroxisomal membrane. Orthologous to human DECR2 (2,4-dienoyl-CoA reductase 2); INTERACTS WITH (+)-schisandrin B; 1-naphthyl isothiocyanate; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: 2,4-dienoyl CoA reductase 2, peroxisomal; 2-4-dienoyl-Coenzyme A reductase 2, peroxisomal; DCR-AKL; Dcrakl; peroxisomal 2,4-dienoyl-CoA reductase; peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]; putative peroxisomal 2,4-dienoyl-CoA reductase; putative peroxisomal 24-dienoyl-CoA reductase; putativeperoxisomal2,4-dienoyl-CoAreductase; putativeperoxisomal24-dienoyl-CoAreductase; pVI-AKL
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,609,389 - 15,617,779 (-)NCBIGRCr8
mRatBN7.21015,104,907 - 15,113,281 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,002,926 - 15,118,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,844,315 - 19,852,298 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,333,200 - 19,341,185 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,832,983 - 14,841,013 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,451,850 - 15,460,227 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,431,638 - 15,465,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,265,550 - 15,273,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,350,593 - 15,358,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,351,563 - 15,359,609 (-)NCBI
Celera1014,773,344 - 14,781,377 (-)NCBICelera
Cytogenetic Map10q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (EXP)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methylcholine  (ISO)
3,3',5-triiodo-L-thyronine  (EXP)
3-chloropropane-1,2-diol  (EXP)
4,4'-diaminodiphenylmethane  (ISO)
acetamide  (EXP)
Aflatoxin B2 alpha  (ISO)
ammonium chloride  (EXP)
arsane  (ISO)
arsenic atom  (ISO)
avobenzone  (ISO)
benzo[a]pyrene  (ISO)
bexarotene  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
Bisphenol B  (ISO)
carbon nanotube  (ISO)
cefaloridine  (EXP)
chromium(6+)  (ISO)
cisplatin  (ISO)
clofibrate  (EXP)
clofibric acid  (EXP)
crocidolite asbestos  (ISO)
cyclosporin A  (ISO)
dichloroacetic acid  (ISO)
diquat  (ISO)
elemental selenium  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenofibrate  (EXP)
flavonoids  (EXP)
flutamide  (EXP)
gemfibrozil  (EXP)
glafenine  (EXP)
gliotoxin  (EXP)
glutathione  (EXP)
indometacin  (EXP)
isobutanol  (ISO)
ivermectin  (ISO)
leflunomide  (EXP)
methapyrilene  (EXP)
methyl methanesulfonate  (ISO)
microcystin-LR  (ISO)
Muraglitazar  (EXP)
NADP zwitterion  (ISO)
NADP(+)  (ISO)
nefazodone  (EXP)
nimesulide  (EXP)
paracetamol  (EXP,ISO)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
phenobarbital  (ISO)
pirinixic acid  (EXP,ISO)
rotenone  (EXP)
selenium atom  (ISO)
sodium arsenite  (EXP)
sunitinib  (ISO)
temozolomide  (ISO)
Tesaglitazar  (EXP)
tetrachloroethene  (ISO)
tetrachloromethane  (EXP,ISO)
tetrahydropalmatine  (ISO)
trichloroethene  (EXP,ISO)
troglitazone  (EXP,ISO)
valproic acid  (ISO)
vancomycin  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Identification of a novel human peroxisomal 2,4-dienoyl-CoA reductase related protein using the M13 phage protein VI phage display technology. Amery L, etal., Comb Chem High Throughput Screen. 2001 Nov;4(7):545-52.
2. Identification of peroxisomal proteins by using M13 phage protein VI phage display: molecular evidence that mammalian peroxisomes contain a 2,4-dienoyl-CoA reductase. Fransen M, etal., Biochem J 1999 Jun 1;340 ( Pt 2):561-8.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Proteomic analysis of rat liver peroxisome: presence of peroxisome-specific isozyme of Lon protease. Kikuchi M, etal., J Biol Chem. 2004 Jan 2;279(1):421-8. Epub 2003 Oct 15.
5. Gene Data Set MGD Curation, June 12, 2002
6. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
7. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
8. GOA pipeline RGD automated data pipeline
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:10811639   PMID:11514237   PMID:15489334   PMID:20178365  


Genomics

Comparative Map Data
Decr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81015,609,389 - 15,617,779 (-)NCBIGRCr8
mRatBN7.21015,104,907 - 15,113,281 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1015,002,926 - 15,118,479 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1019,844,315 - 19,852,298 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01019,333,200 - 19,341,185 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01014,832,983 - 14,841,013 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01015,451,850 - 15,460,227 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1015,431,638 - 15,465,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01015,265,550 - 15,273,903 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41015,350,593 - 15,358,640 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11015,351,563 - 15,359,609 (-)NCBI
Celera1014,773,344 - 14,781,377 (-)NCBICelera
Cytogenetic Map10q12NCBI
DECR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3816401,885 - 412,482 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl16401,858 - 412,487 (+)EnsemblGRCh38hg38GRCh38
GRCh3716451,885 - 462,482 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3616391,859 - 402,488 (+)NCBINCBI36Build 36hg18NCBI36
Build 3416391,858 - 402,487NCBI
Celera16652,405 - 662,884 (+)NCBICelera
Cytogenetic Map16p13.3NCBI
HuRef16370,920 - 381,537 (+)NCBIHuRef
CHM1_116451,798 - 462,431 (+)NCBICHM1_1
T2T-CHM13v2.016398,130 - 408,668 (+)NCBIT2T-CHM13v2.0
Decr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391726,300,182 - 26,309,096 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1726,300,182 - 26,309,311 (-)EnsemblGRCm39 Ensembl
GRCm381726,081,208 - 26,090,322 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1726,081,208 - 26,090,337 (-)EnsemblGRCm38mm10GRCm38
MGSCv371726,218,156 - 26,227,109 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361725,808,811 - 25,817,764 (-)NCBIMGSCv36mm8
Celera1726,615,219 - 26,624,120 (-)NCBICelera
Cytogenetic Map17A3.3NCBI
cM Map1713.06NCBI
Decr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544216,797,190 - 16,807,199 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495544216,799,927 - 16,807,199 (-)NCBIChiLan1.0ChiLan1.0
DECR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v218631,096 - 642,162 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1164,420,568 - 4,430,821 (+)NCBINHGRI_mPanPan1
PanPan1.116395,041 - 406,832 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl16395,158 - 405,928 (+)Ensemblpanpan1.1panPan2
DECR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1640,108,878 - 40,118,760 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl640,111,215 - 40,115,726 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha641,371,650 - 41,381,329 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0640,450,318 - 40,460,010 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl640,450,920 - 40,460,105 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1640,138,713 - 40,148,393 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0640,098,911 - 40,108,594 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0640,578,136 - 40,587,824 (-)NCBIUU_Cfam_GSD_1.0
Decr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344112,444,262 - 112,454,980 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936501547,063 - 552,914 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936501542,365 - 553,541 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DECR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl341,295,648 - 41,304,032 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1341,291,038 - 41,304,044 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2341,124,047 - 41,137,274 (+)NCBISscrofa10.2Sscrofa10.2susScr3
DECR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.15342,006 - 357,369 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl5342,038 - 357,392 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606830,819,836 - 30,830,433 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Decr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046249131,238,173 - 1,244,374 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046249131,237,797 - 1,246,723 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Decr2
40 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:47
Count of miRNA genes:44
Interacting mature miRNAs:44
Transcripts:ENSRNOT00000027518
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
634329Pia15Pristane induced arthritis QTL 153.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10124158324Rat
2293680Bss40Bone structure and strength QTL 405.660.0001femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)10135225947Rat
634327Hc4Hypercalciuria QTL 42.4urine calcium amount (VT:0002985)urine calcium excretion rate (CMO:0000763)10138328221Rat
7411611Foco17Food consumption QTL 1718.70.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)10142315980Rat
70223Bp57Blood pressure QTL 575arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)10180676123Rat
10401803Kidm50Kidney mass QTL 50kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)1041834445418344Rat
631554Bp133Blood pressure QTL 1330.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1074336463851208Rat
1576304Schws7Schwannoma susceptibility QTL 70.0115nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)10476552719816042Rat
631828Alc5Alcohol consumption QTL 52.4consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402717245662Rat
737820Alc9Alcohol consumption QTL 92.2consumption behavior trait (VT:0002069)ethanol drink intake rate (CMO:0001407)10514402719233348Rat
2313064Bmd71Bone mineral density QTL 710.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)10538701450387014Rat
2313066Bss63Bone structure and strength QTL 631.40.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)10538701450387014Rat
2313081Bss64Bone structure and strength QTL 641.30.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)10538701450387014Rat
2313095Bss62Bone structure and strength QTL 621.50.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2313104Bss61Bone structure and strength QTL 610.90.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)10538701450387014Rat
2298544Neuinf9Neuroinflammation QTL 94.6nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)10580199062146030Rat
631660Hcar1Hepatocarcinoma resistance QTL 13.40.0001liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)10615418215990232Rat
8662860Vetf10Vascular elastic tissue fragility QTL 10artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)10615418273453136Rat
61427Cia16Collagen induced arthritis QTL 163.2joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)10635789696121100Rat
1578761Stresp21Stress response QTL 213.3thymus mass (VT:0004954)thymus wet weight (CMO:0000855)10637574651375746Rat
2303118Mamtr7Mammary tumor resistance QTL 70.003mammary gland integrity trait (VT:0010552)mammary tumor growth rate (CMO:0000344)109658275104670812Rat
9590310Scort19Serum corticosterone level QTL 196.30.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9590268Scort13Serum corticosterone level QTL 133.260.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)101147401056474010Rat
9589136Insul27Insulin level QTL 2710.460.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)101147401056474010Rat
2301967Cm73Cardiac mass QTL 734.55heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)101448701189062041Rat
631268Cia21Collagen induced arthritis QTL 213.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1014487011104060283Rat
2316949Gluco60Glucose level QTL 603.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)1014487011107057807Rat
1354587Kidm21Kidney mass QTL 213.3kidney mass (VT:0002707)right kidney wet weight (CMO:0000082)101502851360430477Rat

Markers in Region
RH128482  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21015,114,722 - 15,114,938 (+)MAPPERmRatBN7.2
Rnor_6.01015,461,666 - 15,461,881NCBIRnor6.0
Rnor_5.01015,275,366 - 15,275,581UniSTSRnor5.0
RGSC_v3.41015,360,409 - 15,360,624UniSTSRGSC3.4
Celera1014,783,146 - 14,783,361UniSTS
RH 3.4 Map10155.0UniSTS
Cytogenetic Map10q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 26 42 41 1 41 2 66 35 30 2
Low 1 17 15 18 8 9 8 11 9 8
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000027439   ⟹   ENSRNOP00000027439
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,002,926 - 15,034,733 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000027518   ⟹   ENSRNOP00000027518
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,106,610 - 15,113,068 (-)Ensembl
Rnor_6.0 Ensembl1015,451,852 - 15,459,897 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000027593   ⟹   ENSRNOP00000027593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,114,624 - 15,118,479 (-)Ensembl
Rnor_6.0 Ensembl1015,461,552 - 15,465,413 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000077826   ⟹   ENSRNOP00000068775
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,084,691 - 15,118,479 (-)Ensembl
Rnor_6.0 Ensembl1015,431,638 - 15,465,404 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098691   ⟹   ENSRNOP00000082618
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,002,926 - 15,086,708 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100008   ⟹   ENSRNOP00000095636
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,106,610 - 15,113,081 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000100345   ⟹   ENSRNOP00000080945
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,002,926 - 15,086,708 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104441   ⟹   ENSRNOP00000093315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,106,610 - 15,112,864 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000117914   ⟹   ENSRNOP00000095174
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1015,002,926 - 15,086,708 (-)Ensembl
RefSeq Acc Id: NM_171996   ⟹   NP_741993
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,609,389 - 15,617,436 (-)NCBI
mRatBN7.21015,104,907 - 15,112,954 (-)NCBI
Rnor_6.01015,451,850 - 15,459,897 (-)NCBI
Rnor_5.01015,265,550 - 15,273,903 (-)NCBI
RGSC_v3.41015,350,593 - 15,358,640 (-)RGD
Celera1014,773,344 - 14,781,377 (-)RGD
Sequence:
RefSeq Acc Id: XM_006246024   ⟹   XP_006246086
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,609,389 - 15,617,779 (-)NCBI
mRatBN7.21015,104,907 - 15,113,281 (-)NCBI
Rnor_6.01015,451,850 - 15,460,227 (-)NCBI
Rnor_5.01015,265,550 - 15,273,903 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039086793   ⟹   XP_038942721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,609,389 - 15,617,761 (-)NCBI
mRatBN7.21015,104,907 - 15,113,003 (-)NCBI
RefSeq Acc Id: XM_039086794   ⟹   XP_038942722
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,609,389 - 15,617,488 (-)NCBI
mRatBN7.21015,104,907 - 15,113,003 (-)NCBI
RefSeq Acc Id: XM_039086795   ⟹   XP_038942723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,609,389 - 15,617,491 (-)NCBI
mRatBN7.21015,104,907 - 15,113,006 (-)NCBI
RefSeq Acc Id: XM_063269816   ⟹   XP_063125886
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81015,609,389 - 15,617,759 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_741993   ⟸   NM_171996
- UniProtKB: Q9Z2M4 (UniProtKB/Swiss-Prot),   A6HD86 (UniProtKB/TrEMBL),   A0A8I6AJE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006246086   ⟸   XM_006246024
- Peptide Label: isoform X1
- UniProtKB: Q9Z2M4 (UniProtKB/Swiss-Prot),   A6HD86 (UniProtKB/TrEMBL),   A0A8I6AJE6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068775   ⟸   ENSRNOT00000077826
RefSeq Acc Id: ENSRNOP00000027593   ⟸   ENSRNOT00000027593
RefSeq Acc Id: ENSRNOP00000027518   ⟸   ENSRNOT00000027518
RefSeq Acc Id: XP_038942723   ⟸   XM_039086795
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038942722   ⟸   XM_039086794
- Peptide Label: isoform X2
RefSeq Acc Id: XP_038942721   ⟸   XM_039086793
- Peptide Label: isoform X1
- UniProtKB: Q9Z2M4 (UniProtKB/Swiss-Prot),   A6HD86 (UniProtKB/TrEMBL),   A0A8I6AJE6 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000093315   ⟸   ENSRNOT00000104441
RefSeq Acc Id: ENSRNOP00000080945   ⟸   ENSRNOT00000100345
RefSeq Acc Id: ENSRNOP00000027439   ⟸   ENSRNOT00000027439
RefSeq Acc Id: ENSRNOP00000095174   ⟸   ENSRNOT00000117914
RefSeq Acc Id: ENSRNOP00000082618   ⟸   ENSRNOT00000098691
RefSeq Acc Id: ENSRNOP00000095636   ⟸   ENSRNOT00000100008
RefSeq Acc Id: XP_063125886   ⟸   XM_063269816
- Peptide Label: isoform X1
Protein Domains
EF-hand   FIP-RBD

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z2M4-F1-model_v2 AlphaFold Q9Z2M4 1-292 view protein structure
AF-Q66H66-F1-model_v2 AlphaFold Q66H66 1-446 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13697069
Promoter ID:EPDNEW_R7593
Type:initiation region
Name:Nme4_2
Description:NME/NM23 nucleoside diphosphate kinase 4
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R7594  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01015,459,886 - 15,459,946EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:71002 AgrOrtholog
BioCyc Gene G2FUF-25732 BioCyc
Ensembl Genes ENSRNOG00000032152 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSRNOG00000050424 Ensembl
  ENSRNOG00065010084 UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000027439.4 UniProtKB/TrEMBL
  ENSRNOT00000027518.6 UniProtKB/Swiss-Prot
  ENSRNOT00000077826.2 UniProtKB/TrEMBL
  ENSRNOT00000100008.1 UniProtKB/TrEMBL
  ENSRNOT00000104441 ENTREZGENE
  ENSRNOT00000104441.1 UniProtKB/TrEMBL
  ENSRNOT00065016240 UniProtKB/Swiss-Prot
Gene3D-CATH 1.20.5.2440 UniProtKB/TrEMBL
  3.30.70.141 UniProtKB/TrEMBL
  NAD(P)-binding Rossmann-like Domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Translation factors UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7097883 IMAGE-MGC_LOAD
InterPro DECR2-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
  FIP-RBD_C_sf UniProtKB/TrEMBL
  L3_arc_euk UniProtKB/TrEMBL
  NAD(P)-bd_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDK-like_dom UniProtKB/TrEMBL
  NDK-like_dom_sf UniProtKB/TrEMBL
  Nucleoside_diP_kinase UniProtKB/TrEMBL
  Rab-bd_FIP-RBD UniProtKB/TrEMBL
  Ribosomal_L3 UniProtKB/TrEMBL
  Ribosomal_L3_CS UniProtKB/TrEMBL
  SDR_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Transl_elong_init/rib_B-barrel UniProtKB/TrEMBL
KEGG Report rno:64461 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:91441 IMAGE-MGC_LOAD
NCBI Gene 64461 ENTREZGENE
PANTHER 60S RIBOSOMAL PROTEIN L3 UniProtKB/TrEMBL
  PEROXISOMAL 2,4-DIENOYL-COA REDUCTASE [(3E)-ENOYL-COA-PRODUCING] UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11363 UniProtKB/TrEMBL
  PTHR15726:SF6 UniProtKB/TrEMBL
  PTHR43296 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  RAB11-FAMILY INTERACTING PROTEIN UniProtKB/TrEMBL
Pfam adh_short UniProtKB/TrEMBL
  adh_short_C2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NDK UniProtKB/TrEMBL
  RBD-FIP UniProtKB/TrEMBL
  Ribosomal_L3 UniProtKB/TrEMBL
PhenoGen Decr2 PhenoGen
PRINTS GDHRDH UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NUCDPKINASE UniProtKB/TrEMBL
  SDRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE EF_HAND_2 UniProtKB/TrEMBL
  FIP_RBD UniProtKB/TrEMBL
  RIBOSOMAL_L3 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000032152 RatGTEx
  ENSRNOG00000050424 RatGTEx
  ENSRNOG00065010084 RatGTEx
SMART NDK UniProtKB/TrEMBL
Superfamily-SCOP SSF144270 UniProtKB/TrEMBL
  SSF51735 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF54919 UniProtKB/TrEMBL
  Translat_factor UniProtKB/TrEMBL
UniProt A0A8I6AJE6 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6GLQ6_RAT UniProtKB/TrEMBL
  A6HD86 ENTREZGENE, UniProtKB/TrEMBL
  DECR2_RAT UniProtKB/Swiss-Prot
  F7F3L0_RAT UniProtKB/TrEMBL
  Q6TXF6_RAT UniProtKB/TrEMBL
  Q9Z2M4 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-12-15 Decr2  2,4-dienoyl-CoA reductase 2  Decr2  2,4-dienoyl CoA reductase 2, peroxisomal  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-26 Decr2  2,4-dienoyl CoA reductase 2, peroxisomal  Decr2  2-4-dienoyl-Coenzyme A reductase 2, peroxisomal  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2002-07-09 Decr2  2-4-dienoyl-Coenzyme A reductase 2, peroxisomal      Symbol and Name updated to reflect Human and Mouse nomenclature 70877 APPROVED

RGD Curation Notes
Note Type Note Reference
gene_cellular_localization localized to peroxisome