| 1,3-dinitrobenzene | increases expression | EXP | | 6480464 | 3-dinitrobenzene results in increased expression of AKR1B8 mRNA | CTD | PMID:21983209 |
| 1-phenyl-1,2-propanedione | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of 1-phenyl-1,2-propanedione | CTD | PMID:18845131 |
| 17alpha-ethynylestradiol | increases expression | EXP | | 6480464 | Ethinyl Estradiol results in increased expression of AKR1B8 mRNA | CTD | PMID:17557909 |
| 17alpha-ethynylestradiol | decreases expression | EXP | | 6480464 | Ethinyl Estradiol results in decreased expression of AKR1B8 mRNA | CTD | PMID:17108234 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:1550101 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AKR1B8 mRNA | CTD | PMID:16960034 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:1550101 | 6480464 | Tetrachlorodibenzodioxin affects the expression of AKR1B8 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AKR1B8 mRNA | CTD | PMID:16960034 PMID:21215274 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in increased expression of AKR1B8 mRNA | CTD | PMID:16960034 |
| 2,4,6-trinitrotoluene | affects expression | EXP | | 6480464 | Trinitrotoluene affects the expression of AKR1B8 mRNA | CTD | PMID:21346803 |
| 2-amino-2-deoxy-D-glucopyranose | increases expression | EXP | | 6480464 | Glucosamine results in increased expression of AKR1B8 mRNA | CTD | PMID:17109745 |
| 2-hexenal | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of 2-hexenal | CTD | PMID:18845131 |
| 2-nonenal | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of 2-nonenal | CTD | PMID:18845131 |
| 3-deoxyglucosone | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of 3-deoxyglucosone | CTD | PMID:18845131 |
| 4-hydroxynon-2-enal | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of 4-hydroxy-2-nonenal | CTD | PMID:18845131 |
| 4-nitrobenzaldehyde | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of 4-nitrobenzaldehyde | CTD | PMID:18845131 |
| acrolein | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of Acrolein | CTD | PMID:18845131 |
| aldehydo-D-glucosamine | increases expression | EXP | | 6480464 | Glucosamine results in increased expression of AKR1B8 mRNA | CTD | PMID:17109745 |
| all-trans-retinoic acid | increases expression | EXP | | 6480464 | Tretinoin results in increased expression of AKR1B8 mRNA | CTD | PMID:20488242 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of AKR1B8 mRNA | CTD | PMID:16483693 |
| aristolochic acid | increases expression | EXP | | 6480464 | aristolochic acid I results in increased expression of AKR1B8 mRNA | CTD | PMID:17483316 |
| arsenic atom | increases expression | EXP | | 6480464 | Arsenic results in increased expression of AKR1B8 mRNA | CTD | PMID:18315880 |
| arsenite(3-) | increases expression | EXP | | 6480464 | arsenite results in increased expression of AKR1B8 protein | CTD | PMID:15175009 |
| arsenite(3-) | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [arsenite results in increased expression of AKR1B8 protein]; more ... | CTD | PMID:15175009 |
| benzaldehyde | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of benzaldehyde | CTD | PMID:18845131 |
| benzbromarone | decreases activity | EXP | | 6480464 | Benzbromarone results in decreased activity of AKR1B8 protein | CTD | PMID:18845131 |
| benzo[a]pyrene | decreases expression | EXP | | 6480464 | Benzo(a)pyrene results in decreased expression of AKR1B8 mRNA | CTD | PMID:21839799 |
| benzo[a]pyrene | increases expression | ISO | RGD:1550101 | 6480464 | Benzo(a)pyrene results in increased expression of AKR1B8 mRNA | CTD | PMID:19770486 |
| benzyl alcohol | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the oxidation of Benzyl Alcohol | CTD | PMID:18845131 |
| beta-D-glucosamine | increases expression | EXP | | 6480464 | Glucosamine results in increased expression of AKR1B8 mRNA | CTD | PMID:17109745 |
| bis(2-ethylhexyl) phthalate | increases expression | EXP | | 6480464 | Diethylhexyl Phthalate results in increased expression of AKR1B8 mRNA | CTD | PMID:19560483 |
| butan-1-ol | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the oxidation of 1-Butanol | CTD | PMID:18845131 |
| butanal | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of butyraldehyde | CTD | PMID:18845131 |
| butane-2,3-dione | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of Diacetyl | CTD | PMID:18845131 |
| cefaloridine | increases expression | EXP | | 6480464 | Cephaloridine results in increased expression of AKR1B8 mRNA | CTD | PMID:18500788 |
| chloroprene | increases expression | EXP | | 6480464 | Chloroprene results in increased expression of AKR1B8 mRNA | CTD | PMID:23125180 |
| chloroprene | increases expression | ISO | RGD:1550101 | 6480464 | Chloroprene results in increased expression of AKR1B8 mRNA | CTD | PMID:23125180 |
| choline | multiple interactions | ISO | RGD:1550101 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B8 mRNA | CTD | PMID:20938992 |
| coumarin | increases expression | EXP | | 6480464 | coumarin results in increased expression of AKR1B8 mRNA | CTD | PMID:18480146 |
| curcumin | increases expression | EXP | | 6480464 | Curcumin results in increased expression of AKR1B8 mRNA | CTD | PMID:18299980 |
| D-glyceraldehyde | increases metabolic processing | ISO | RGD:3516654 | 6480464 | AKR1B15 protein results in increased metabolism of Glyceraldehyde | CTD | PMID:21276782 |
| decan-1-ol | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the oxidation of n-decyl alcohol | CTD | PMID:18845131 |
| dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of AKR1B8 mRNA | CTD | PMID:19560483 |
| dipentyl phthalate | increases expression | EXP | | 6480464 | di-n-pentyl phthalate results in increased expression of AKR1B8 mRNA | CTD | PMID:19560483 |
| diuron | increases expression | EXP | | 6480464 | Diuron results in increased expression of AKR1B8 mRNA | CTD | PMID:21551480 |
| flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of AKR1B8 protein | CTD | PMID:17311803 |
| folic acid | multiple interactions | ISO | RGD:1550101 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B8 mRNA | CTD | PMID:20938992 |
| glutathione | multiple interactions | EXP | | 6480464 | Glutathione inhibits the reaction [arsenite results in increased expression of AKR1B8 protein] | CTD | PMID:15175009 |
| glyceraldehyde | increases metabolic processing | ISO | RGD:3516654 | 6480464 | AKR1B15 protein results in increased metabolism of Glyceraldehyde | CTD | PMID:21276782 |
| glycolaldehyde | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of glycolaldehyde | CTD | PMID:18845131 |
| glyoxal | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of Glyoxal | CTD | PMID:18845131 |
| hypochlorous acid | increases expression | ISO | RGD:1550101 | 6480464 | Hypochlorous Acid results in increased expression of AKR1B8 mRNA | CTD | PMID:19376150 |
| indan-1-ol | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the oxidation of 1-indanol | CTD | PMID:18845131 |
| indole-3-methanol | affects expression | EXP | | 6480464 | indole-3-carbinol affects the expression of AKR1B8 mRNA | CTD | PMID:21396975 |
| indole-3-methanol | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of AKR1B8 mRNA | CTD | PMID:22129741 |
| isatin | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of Isatin | CTD | PMID:18845131 |
| L-methionine | multiple interactions | ISO | RGD:1550101 | 6480464 | [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of AKR1B8 mRNA | CTD | PMID:20938992 |
| methylglyoxal | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of Pyruvaldehyde | CTD | PMID:18845131 |
| myricetin | decreases activity | EXP | | 6480464 | myricetin results in decreased activity of AKR1B8 protein | CTD | PMID:18845131 |
| N-acetyl-L-cysteine | multiple interactions | EXP | | 6480464 | Acetylcysteine inhibits the reaction [arsenite results in increased expression of AKR1B8 protein] | CTD | PMID:15175009 |
| N-methyl-N-nitrosurea | increases expression | EXP | | 6480464 | Methylnitrosourea results in increased expression of AKR1B8 protein | CTD | PMID:11565795 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of AKR1B8 mRNA | CTD | PMID:18164116 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of AKR1B8 mRNA | CTD | PMID:22129741 |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of AKR1B8 protein | CTD | PMID:11565795 |
| N-nitrosodiethylamine | increases expression | EXP | | 6480464 | Diethylnitrosamine results in increased expression of AKR1B8 mRNA | CTD | PMID:19638242 |
| NADP zwitterion | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the oxidation of 1-Butanol; more ... | CTD | PMID:18845131 |
| NADP(+) | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the oxidation of 1-Butanol; more ... | CTD | PMID:18845131 |
| nickel dichloride | affects expression | EXP | | 6480464 | nickel chloride affects the expression of AKR1B8 mRNA | CTD | PMID:22110744 |
| nonan-1-ol | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the oxidation of 1-nonanol | CTD | PMID:18845131 |
| ozone | multiple interactions | ISO | RGD:1550101 | 6480464 | TTPA protein affects the reaction [Ozone results in increased expression of AKR1B8 mRNA] | CTD | PMID:19555225 |
| ozone | increases expression | EXP | | 6480464 | Ozone results in increased expression of AKR1B8 mRNA | CTD | PMID:16716893 |
| paracetamol | affects expression | ISO | RGD:1550101 | 6480464 | Acetaminophen affects the expression of AKR1B8 mRNA | CTD | PMID:17562736 |
| pentane-2,3-dione | multiple interactions | EXP | | 6480464 | [AKR1B8 protein co-treated with NADP] affects the reduction of 2,3-pentanedione | CTD | PMID:18845131 |
| phenacetin | increases expression | EXP | | 6480464 | Phenacetin results in increased expression of AKR1B8 mRNA | CTD | PMID:17698508 |
| phenylhydrazine | increases expression | EXP | | 6480464 | phenylhydrazine results in increased expression of AKR1B8 mRNA | CTD | PMID:17698508 |
| phosgene | affects expression | ISO | RGD:1550101 | 6480464 | Phosgene affects the expression of AKR1B8 mRNA | CTD | PMID:16300373 |
| pirinixic acid | multiple interactions | ISO | RGD:1550101 | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of AKR1B8 mRNA | CTD | PMID:18489776 |
| pirinixic acid | increases expression | ISO | RGD:1550101 | 6480464 | pirinixic acid results in increased expression of AKR1B8 mRNA | CTD | PMID:17426115 |
| quercetin | increases expression | EXP | | 6480464 | Quercetin results in increased expression of AKR1B8 mRNA | CTD | PMID:19191009 |
| quercetin | decreases activity | EXP | | 6480464 | Quercetin results in decreased activity of AKR1B8 protein | CTD | PMID:18845131 |
| sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of AKR1B8 mRNA | CTD | PMID:22110744 |
| sodium dichromate | increases expression | ISO | RGD:1550101 | 6480464 | sodium bichromate results in increased expression of AKR1B8 mRNA | CTD | PMID:22155349 |
| sorbinil | decreases activity | EXP | | 6480464 | sorbinil results in decreased activity of AKR1B8 protein | CTD | PMID:18845131 |
| tert-butyl hydroperoxide | increases expression | ISO | RGD:1550101 | 6480464 | tert-Butylhydroperoxide results in increased expression of AKR1B8 mRNA | CTD | PMID:15003993 |
| tolrestat | decreases activity | EXP | | 6480464 | tolrestat results in decreased activity of AKR1B8 protein | CTD | PMID:18845131 |
| ursodeoxycholic acid | increases expression | EXP | | 6480464 | Ursodeoxycholic Acid results in increased expression of AKR1B8 mRNA | CTD | PMID:15885361 |
| valproic acid | increases expression | ISO | RGD:1550101 | 6480464 | Valproic Acid results in increased expression of AKR1B8 mRNA | CTD | PMID:20546886 |
| vancomycin | decreases expression | ISO | RGD:1550101 | 6480464 | Vancomycin results in decreased expression of AKR1B8 mRNA | CTD | PMID:18930951 |
| zearalenone | decreases activity | EXP | | 6480464 | Zearalenone results in decreased activity of AKR1B8 protein | CTD | PMID:18845131 |
| zinc atom | multiple interactions | EXP | | 6480464 | Zinc inhibits the reaction [Zinc deficiency results in increased expression of AKR1B8 mRNA] | CTD | PMID:16140947 |
| zinc atom | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of AKR1B8 mRNA | CTD | PMID:16140947 |
| zinc(0) | multiple interactions | EXP | | 6480464 | Zinc inhibits the reaction [Zinc deficiency results in increased expression of AKR1B8 mRNA] | CTD | PMID:16140947 |
| zinc(0) | increases expression | EXP | | 6480464 | Zinc deficiency results in increased expression of AKR1B8 mRNA | CTD | PMID:16140947 |