Annotation (Toggle Detail/Summary View) | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | anterior/posterior pattern specification | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:4422144 PMID:19754878 | anterior/posterior pattern specification | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | cell adhesion | | IMP | | 1299440 | | RGD | | cell fate specification | | ISO | RGD:733697 | 1624291 | MGI:MGI:98297 | RGD | MGI:MGI:3624618 PMID:16647304 | cell fate specification | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | cerebral cortex development | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:3625667 PMID:16648472 | cerebral cortex development | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | embryonic body morphogenesis | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:3624617 PMID:16647303 | embryonic body morphogenesis | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | embryonic body morphogenesis | | ISO | RGD:733697 | 1624291 | MGI:MGI:98297 | RGD | MGI:MGI:3624618 PMID:16647304 | embryonic morphogenesis | | ISO | RGD:733697 | 1624291 | MGI:MGI:95655 | RGD | MGI:MGI:3710451 PMID:17504941 | embryonic retina morphogenesis in camera-type eye | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:4422144 PMID:19754878 | embryonic retina morphogenesis in camera-type eye | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | lens development in camera-type eye | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:4422144 PMID:19754878 | lens development in camera-type eye | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | myoblast fusion | | ISO | RGD:733697 | 1624291 | MGI:MGI:3521604|PMID:15520228 | RGD | MGI:MGI:3521604 PMID:15520228 | myoblast fusion | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of MAPK cascade | | ISO | RGD:733697 | 1624291 | MGI:MGI:3850924|PMID:19244314 | RGD | MGI:MGI:3850924 PMID:19244314 | positive regulation of MAPK cascade | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of MAPK cascade | | ISO | RGD:733697 | 1624291 | MGI:MGI:88355|MGI:MGI:109327|MGI:MGI:1918084 | RGD | MGI:MGI:4439190 PMID:20160094 | positive regulation of neural precursor cell proliferation | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:3625667 PMID:16648472 | positive regulation of neural precursor cell proliferation | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of neuron differentiation | | ISO | RGD:733697 | 1624291 | MGI:MGI:3625667|PMID:16648472 | RGD | MGI:MGI:3625667 PMID:16648472 | positive regulation of neuron differentiation | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of neuron differentiation | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:3850924 PMID:19244314 | positive regulation of protein phosphorylation | | ISO | RGD:733697 | 1624291 | MGI:MGI:3522534|PMID:15572127 | RGD | MGI:MGI:3522534 PMID:15572127 | positive regulation of protein phosphorylation | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of skeletal muscle tissue development | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:3522534 PMID:15572127 | positive regulation of skeletal muscle tissue development | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of small GTPase mediated signal transduction | | ISO | RGD:733697 | 1624291 | MGI:MGI:3850924|PMID:19244314 | RGD | MGI:MGI:3850924 PMID:19244314 | positive regulation of small GTPase mediated signal transduction | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of transcription from RNA polymerase II promoter | | ISO | RGD:733697 | 1624291 | MGI:MGI:97275 | RGD | MGI:MGI:3522534 PMID:15572127 | positive regulation of transcription from RNA polymerase II promoter | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | positive regulation of transcription from RNA polymerase II promoter | | ISO | RGD:733697 | 1624291 | MGI:MGI:97275|MGI:MGI:107754 | RGD | MGI:MGI:3625667 PMID:16648472 | regulation of neuron differentiation | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:3625667 PMID:16648472 | regulation of protein heterodimerization activity | | ISO | RGD:733697 | 1624291 | MGI:MGI:3522534|PMID:15572127 | RGD | MGI:MGI:3522534 PMID:15572127 | regulation of protein heterodimerization activity | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | regulation of protein heterodimerization activity | | ISO | RGD:733697 | 1624291 | MGI:MGI:3625667|PMID:16648472 | RGD | MGI:MGI:3625667 PMID:16648472 | satellite cell differentiation | | ISO | RGD:733697 | 1624291 | MGI:MGI:2653120 | RGD | MGI:MGI:3522534 PMID:15572127 | satellite cell differentiation | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | smoothened signaling pathway | | ISO | RGD:733697 | 1624291 | MGI:MGI:98297 | RGD | MGI:MGI:3624618 PMID:16647304 | smoothened signaling pathway | | IDA | | | PMID:16647303 | MGI | PMID:16647303 | smoothened signaling pathway | | IEA | Ensembl:ENSMUSP00000045547 | 1600115 | GO_REF:0000019 | ENSEMBL | GO_REF:0000019 | striated muscle cell differentiation | | ISO | RGD:733697 | 1624291 | MGI:MGI:88355|MGI:MGI:109327|MGI:MGI:1918084|MGI:MGI:1346865 | RGD | MGI:MGI:4439190 PMID:20160094 | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Pathway Annotations| External Database Links | |
| Pathway Interaction Database | Signaling events mediated by the Hedgehog family (PID:200168) |
Gene-Chemical Interaction Annotations
|
|
|
Gene Ontology Annotations
|
|
|
|
Molecular Pathway Annotations
|
| External Database Links | |
| Pathway Interaction Database | Signaling events mediated by the Hedgehog family (PID:200168) |
References - curated| 1. |
Beachy PA, etal., Genes Dev. 2010 Sep 15;24(18):2001-12. |
| 2. |
Cuadrado A and Nebreda AR, Biochem J. 2010 Aug 1;429(3):403-17. doi: 10.1042/BJ20100323. |
| 3. |
Kang JS, etal., J Cell Biol 1997 Jul 14;138(1):203-13. |
| 4. |
MGD data from the GO Consortium |
| 5. |
Pipeline to import Pathway Interaction Database annotations from NCI into RGD |
| 6. |
RGD automated import pipeline for gene-chemical interactions |
| 7. |
RGD comprehensive gene curation |
References - uncurated| PubMed | 16647303 |
RGD Disease Portals| Cdon has been annotated in the following RGD Disease Portals. |
|||||
![]() |
| ||||
![]() |
| ||||
![]() |
| ||||
![]() |
| ||||
![]() |
| ||||
![]() |
| ||||
![]() |
| ||||
Comparative Map Data| Cdon (Rattus norvegicus) |
|
||||||||||||||||||||||||||||||||||||||||
| CDON (Homo sapiens) |
|
||||||||||||||||||||||||||||||||||||||||
| Cdon (Mus musculus) |
|
Position Markers| AF090866 |
|
QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. | ![]() | Full Report | ![]() | CSV | ![]() | TAB | ![]() | Printer | ![]() | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_017358 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06054065 | (Get FASTA) | Search GEO for Microarray Profiles |
| AAHX01054053 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF004840 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH474007 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_017358 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_059054 | ||||||||||||||||||||
| Peptide Label: | precursor | ||||||||||||||||||||
| Position: |
|
Protein Sequences| Protein RefSeqs | NP_059054 | (Get FASTA) |
| GenBank Protein | AAC34735 | (Get FASTA) |
| EDL83270 | (Get FASTA) | |
| O35158 | (Get FASTA) |
Strain Sequence Variants
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
|
||||||||||||||||||||
External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000011789 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000016247 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOP00000061569 | UniProtKB/TrEMBL | |
| Ensembl Transcript | ENSRNOT00000016248 | ENTREZGENE, UniProtKB/TrEMBL |
| ENSRNOT00000065358 | UniProtKB/TrEMBL | |
| Entrez Gene | 50938 | ENTREZGENE |
| Gene3D-CATH | Ig-like_fold | UniProtKB/Swiss-Prot |
| Germonline | ENSRNOG00000011789 | UniProtKB/Swiss-Prot |
| HomoloGene Group ID | 22996 | ENTREZGENE |
| InterPro | FN_III | UniProtKB/Swiss-Prot |
| Ig-like | UniProtKB/Swiss-Prot | |
| Ig-like_fold | UniProtKB/Swiss-Prot | |
| Ig_I-set | UniProtKB/Swiss-Prot | |
| Ig_sub | UniProtKB/Swiss-Prot | |
| Ig_sub2 | UniProtKB/Swiss-Prot | |
| IPI | IPI00206284 | UniProtKB/Swiss-Prot |
| IPI00758456 | UniProtKB/Swiss-Prot | |
| IPI00958927 | UniProtKB/TrEMBL | |
| KEGG Report | rno:50938 | ENTREZGENE, UniProtKB/Swiss-Prot |
| Pfam | fn3 | UniProtKB/Swiss-Prot |
| I-set | UniProtKB/Swiss-Prot | |
| PROSITE | FN3 | UniProtKB/Swiss-Prot |
| IG_LIKE | UniProtKB/Swiss-Prot | |
| SMART | FN3 | UniProtKB/Swiss-Prot |
| IGc2 | UniProtKB/Swiss-Prot | |
| SM00409 | UniProtKB/Swiss-Prot | |
| Superfamily-SCOP | FN_III-like | UniProtKB/Swiss-Prot |
| UniGene | Rn.10818 | ENTREZGENE |
| UniProt | CDON_RAT | UniProtKB/Swiss-Prot |
| D4A0K7_RAT | UniProtKB/TrEMBL | |
| G3V7K7_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2012-12-18 | Cdon | cell adhesion associated, oncogene regulated | Cdon | Cdon homolog (mouse) | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2008-09-09 | Cdon | Cdon homolog (mouse) | Cdon | cell adhesion molecule-related/down-regulated by oncogenes | Nomenclature updated to reflect human and mouse nomenclature | 10779 | APPROVED |
| 2004-09-10 | Cdon | cell adhesion molecule-related/down-regulated by oncogenes | Cdo | immunoglobulin superfamily member | Symbol and Name updated | 10779 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_expression | expressed at low levels in most adult rat tissues | 1299440 |
| gene_regulation | rapidly and transiently down-regulated by serum stimulation and constitutively down-regulated in oncogene-transformed cells | 1299440 |
| More on Cdon | |
![]() |
Entrez Gene |
![]() |
Ensembl Gene |
![]() | Genome Browser |
![]() |
NCBI Map Viewer |
![]() |
Vista |
![]() |
Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 708433 |
| Created: | 2003-09-23 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.




