Gene: Plce1 (phospholipase C, epsilon 1) Rattus norvegicus
Symbol: Plce1
Name: phospholipase C, epsilon 1
Description: ENCODES a protein that exhibits phosphatidylinositol phospholipase C activity; Ras GTPase binding; enzyme binding (ortholog); INVOLVED IN G-protein coupled receptor signaling pathway; Ras protein signal transduction; activation of MAPK activity (ortholog); PARTICIPATES IN calcium/calcium-mediated signaling pathway; inositol phosphate metabolic pathway; phosphatidylinositol 3-kinase signaling pathway; ASSOCIATED WITH Mesangial Sclerosis, Diffuse (ortholog); Nephrotic Syndrome (ortholog); Nephrotic Syndrome, Type 2 (ortholog); FOUND IN cytoplasm; cytosol (ortholog); plasma membrane (ortholog); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 3,3',4,4',5-pentachlorobiphenyl
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase epsilon-1; phosphoinositide phospholipase C-epsilon-1; phosphoinositide-specific phospholipase C epsilon-1; phospholipase C epsilon; phospholipase C epsilon 1; phospholipase C, epsilon; phospholipase C-epsilon-1; PLC-epsilon-1; Plce
Orthologs:
Allele / Splice: Plce1Tn(sb-T2/Bart3)2.146Mcwi  
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01257,156,023 - 257,465,440 (+)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01264,652,842 - 264,956,664 (+)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41242,794,858 - 243,103,437 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11242,891,416 - 243,199,995 (+)NCBI
Celera1233,337,820 - 233,642,815 (+)NCBI
Cytogenetic Map1q53NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Plce1
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 69424
Created: 2001-11-27
Species: Rattus norvegicus
Last Modified: 2016-09-13
Status: ACTIVE