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Gene Ontology AnnotationsGene Ontology Annotations
Gene Ontology AnnotationsBiological Process Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | negative regulation of cAMP biosynthetic process | | IMP | | 6902943 | | RGD | | positive regulation of cell growth involved in cardiac muscle cell development | | IMP | | 6902940 | | RGD | | positive regulation of protein phosphatase type 2B activity | | IMP | | 2312613 | | RGD | | regulation of protein kinase A signaling cascade | | IMP | | 68716 | | RGD | | | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Molecular Pathway AnnotationsGene-Chemical Interaction Annotations
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Gene Ontology Annotations
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Molecular Pathway Annotations
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References - curated| 1. |
Alday A, etal., Channels (Austin). 2010 May-Jun;4(3):168-78. |
| 2. |
Carnegie GK, etal., IUBMB Life. 2009 Apr;61(4):394-406. |
| 3. |
Dodge KL, etal., EMBO J 2001 Apr 17;20(8):1921-30. |
| 4. |
GOA data from the GO Consortium |
| 5. |
Kapiloff MS, etal., J Biol Chem. 2009 Aug 28;284(35):23540-6. Epub 2009 Jul 1. |
| 6. |
Kapiloff MS, etal., J Cell Sci 1999 Aug;112 ( Pt 16):2725-36. |
| 7. |
McCartney S, etal., J Biol Chem. 1995 Apr 21;270(16):9327-33. |
| 8. |
NCBI rat LocusLink and RefSeq merged data July 26, 2002 |
| 9. |
Pare GC, etal., Exp Cell Res. 2005 Feb 15;303(2):388-99. |
| 10. |
Pare GC, etal., J Cell Sci. 2005 Dec 1;118(Pt 23):5637-46. |
| 11. |
RGD automated import pipeline for gene-chemical interactions |
| 12. |
Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67. |
| 13. |
Zhang L, etal., J Biol Chem. 2011 Jul 1;286(26):23012-21. Epub 2011 May 5. |
References - uncuratedRGD Disease Portals| Akap6 has been annotated in the following RGD Disease Portals. |
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Comparative Map Data| Akap6 (Rattus norvegicus) |
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| AKAP6 (Homo sapiens) |
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| Akap6 (Mus musculus) |
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Position Markers| D6Got90 |
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| D6Got91 |
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| D6Wox36 |
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| AU047448 |
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| RH132511 |
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| BM384496 |
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QTLs in Region (RGSC Genome Assembly v3.4)| The following QTLs overlap with this region. |  | Full Report | | CSV | | TAB | | Printer | | Gviewer |
Nucleotide Sequences| Nucleotide RefSeqs | NM_022618 | (Get FASTA) | Search GEO for Microarray Profiles |
| GenBank Nucleotide | AABR06044028 | (Get FASTA) | Search GEO for Microarray Profiles |
| AABR06044029 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044030 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044031 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044032 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044033 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044034 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044035 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044036 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044037 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AABR06044038 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044131 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044132 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044133 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044134 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044135 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044136 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044137 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044138 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044139 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044140 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044141 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044142 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044143 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044144 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044145 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044146 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044147 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AAHX01044148 | (Get FASTA) | Search GEO for Microarray Profiles | |
| AF139518 | (Get FASTA) | Search GEO for Microarray Profiles | |
| CH473947 | (Get FASTA) | Search GEO for Microarray Profiles |
| RefSeq Acc Id: | NM_022618 | ||||||||||||||||||||
| RefSeq Status: | PROVISIONAL | ||||||||||||||||||||
| Type: | CODING | ||||||||||||||||||||
| Protein Acc Id: | NP_072140 | ||||||||||||||||||||
| Position: |
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Protein Sequences| Protein RefSeqs | NP_072140 | (Get FASTA) |
| GenBank Protein | AAD39150 | (Get FASTA) |
| EDM03393 | (Get FASTA) | |
| Q9WVC7 | (Get FASTA) |
Strain Sequence Variants
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External Database Links| Database | Acc Id | Source(s) |
| Ensembl Genes | ENSRNOG00000004841 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Protein | ENSRNOP00000006562 | ENTREZGENE, UniProtKB/TrEMBL |
| Ensembl Transcript | ENSRNOT00000006562 | ENTREZGENE, UniProtKB/TrEMBL |
| Entrez Gene | 64553 | ENTREZGENE |
| HomoloGene Group ID | 3157 | ENTREZGENE |
| InterPro | AKAP6/CEP68 | UniProtKB/Swiss-Prot |
| Spectrin/alpha-actinin | UniProtKB/Swiss-Prot | |
| Spectrin_repeat | UniProtKB/Swiss-Prot | |
| IPI | IPI00204907 | UniProtKB/Swiss-Prot |
| KEGG Report | rno:64553 | ENTREZGENE, UniProtKB/Swiss-Prot |
| PANTHER | PTHR14514 | UniProtKB/Swiss-Prot |
| Pfam | Spectrin | UniProtKB/Swiss-Prot |
| SMART | SPEC | UniProtKB/Swiss-Prot |
| UniGene | Rn.147642 | ENTREZGENE |
| UniProt | AKAP6_RAT | UniProtKB/Swiss-Prot |
| G3V6M0_RAT | UniProtKB/TrEMBL |
Nomenclature History| Date | Current Symbol | Current Name | Previous Symbol | Previous Name | Description | Reference | Status |
|---|---|---|---|---|---|---|---|
| 2002-06-10 | Akap6 | A kinase (PRKA) anchor protein 6 | Name updated | 1488 | APPROVED |
RGD Curation Notes| Note Type | Note | Reference |
|---|---|---|
| gene_function | anchoring protein that binds to Pde4d at perinuclear regions in hypertrophic cardiomyocytes | 68716 |
| gene_function | anchoring protein that binds to Pde4d at perinuclear regions in hypertrophic cardiomyocytes | 69370 |
| gene_process | orients and sustains multi-component signaling complexes of protein kinase A and other enzymes | 68716 |
| gene_process | orients and sustains multi-component signaling complexes of protein kinase A and other enzymes | 69370 |
| More on Akap6 | |
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Entrez Gene |
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Ensembl Gene |
| Genome Browser |
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NCBI Map Viewer |
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Vista |
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Vista + UCSC |
| RGD Object Information | |
| RGD ID: | 69412 |
| Created: | 2001-11-27 |
| Species: | Rattus norvegicus |
| Last Modified: | 2013-04-16 |
| Status: | ACTIVE |
© Bioinformatics Program, HMGC at the Medical College of Wisconsin
RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.