Gene: Sost (sclerostin) Rattus norvegicus
Symbol: Sost
Name: sclerostin
Description: ENCODES a protein that exhibits transcription factor binding (ortholog); INVOLVED IN ossification; cellular response to parathyroid hormone stimulus (ortholog); negative regulation of BMP signaling pathway (ortholog); PARTICIPATES IN Wnt signaling, canonical pathway; ASSOCIATED WITH Craniodiaphyseal Dysplasia, Autosomal Dominant (ortholog); Osteochondrodysplasias (ortholog); Sclerosteosis (ortholog); FOUND IN extracellular space; Golgi apparatus; protein complex; INTERACTS WITH aflatoxin B1; ammonium chloride; bisphenol A
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: sclerosteosis
Orthologs:
Homo sapiens : SOST (sclerostin)  HGNC
Mus musculus : Sost (sclerostin)  MGI
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01089,897,087 - 89,900,131 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.01089,689,512 - 89,692,559 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.41091,023,712 - 91,026,759 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11091,038,081 - 91,041,129 (-)NCBI
Celera1085,631,705 - 85,634,749 (-)NCBI
Cytogenetic Map10q32.1NCBImapview
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Sost
Entrez Gene
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista
Vista + UCSC

RGD Object Information
RGD ID: 69358
Created: 2001-11-14
Species: Rattus norvegicus
Last Modified: 2016-05-31
Status: ACTIVE