Gene: Pawr (pro-apoptotic WT1 regulator) Rattus norvegicus
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Symbol: Pawr
Name: pro-apoptotic WT1 regulator
Description: ENCODES a protein that exhibits actin binding; protein kinase C binding; protein phosphatase 1 binding; INVOLVED IN actin filament bundle assembly; activation of cysteine-type endopeptidase activity; apoptotic process; PARTICIPATES IN ceramide signaling pathway; ASSOCIATED WITH Acute Lung Injury; Brain Injuries; Depressive Disorder; FOUND IN actin filament; axon; cytoplasm; INTERACTS WITH (+)-alpha-tocopherol; (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; (S)-colchicine
Type: protein-coding
RefSeq Status: PROVISIONAL
Also known as: Par-4; par-4 induced by effectors of apoptosis; Par4; PRKC apoptosis WT1 regulator; PRKC, apoptosis, WT1, regulator; prostate apoptosis response 4 protein; prostate apoptosis response protein 4; transcriptional repressor Par-4-like protein PAWR
Orthologs:
Homo sapiens (human) : PAWR (pro-apoptotic WT1 regulator)  HGNC
Mus musculus (house mouse) : Pawr (PRKC, apoptosis, WT1, regulator)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Pawr (pro-apoptotic WT1 regulator)
Pan paniscus (bonobo/pygmy chimpanzee) : PAWR (pro-apoptotic WT1 regulator)
Canis lupus familiaris (dog) : PAWR (pro-apoptotic WT1 regulator)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Pawr (pro-apoptotic WT1 regulator)
more info ...
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.0751,273,764 - 51,353,700 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.0751,286,663 - 51,366,383 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.4747,040,162 - 47,119,613 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1747,060,432 - 47,139,881 (+)NCBI
Celera740,512,247 - 40,591,588 (+)NCBI
Cytogenetic Map7q21NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals

Genomics

Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Transcriptome

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
 
More on Pawr
NCBI Gene
Ensembl Gene
JBrowse: rn5 rn6
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RGD Object Information
RGD ID: 69065
Created: 2001-11-08
Species: Rattus norvegicus
Last Modified: 2017-07-11
Status: ACTIVE