Kcnmb1<sup>em1Mcwi</sup> (potassium large conductance calcium-activated channel, subfamily M, beta member 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) - Rat Genome Database

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Gene: Kcnmb1em1Mcwi (potassium large conductance calcium-activated channel, subfamily M, beta member 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin) Rattus norvegicus
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Symbol: Kcnmb1em1Mcwi
Name: potassium large conductance calcium-activated channel, subfamily M, beta member 1; zinc finger nuclease induced mutant 1, Medical College of Wisconsin
RGD ID: 6893415
Description: This allele was made by ZFN mutagenesis. The resulting allele is a net 4-bp deletion in exon 2 (del 441-447, ins. Tct)
Type: allele  of Kcnmb1  
Previously known as: Kcnmb1^[em1Mcwi]; Kcnmb1em1Mcwi
Is Marker For: Strains:   SS-Kcnmb1em1Mcwi  
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Cytogenetic Map10 RGD


References

References - curated
# Reference Title Reference Citation
1. Knockout rats via embryo microinjection of zinc-finger nucleases. Geurts AM, etal., Science. 2009 Jul 24;325(5939):433.
2. PhysGen Knockouts PhysGen Knockout strains

Genomics

Allelic Variants
Name Chromosome Start Pos End Pos Reference Nucleotide Variant Nucleotide Variant Type Assembly
Kcnmb1em1Mcwi-var1 chr10 18911938 18919640 ATCTGTTTCCCAGGAGACTCTGGAAAACGCAGGGGCAGAGTCCCCAACAGCAGCTGAGGGCTGCAAGAGACTAGGTACCTGCTTGTGGAGTTTTTTGTCCCGGAGCAAGCTGTGTGCTCAGACTTGACCATGTTTGGGCATGGAGGCTCGACCCAGATGGAACTGAAGACTGCTTCCCTAGAGACCAACTGGAGACCAAACTTCCTGCTAGAGCTCCAAGGCCTGACTTGGGGTGGGGGGGTGGGGGCCAGTGGAGAGAAACCATCTGCCAGCGGAGACCCAGGGAACTGTGAGTGCTACATCCCTGAGAGTTTGGGAAAGGCTTCTGGGAAGCCAGGGCTGAGGGGAGATGGTGGGAGACAGCAGCCTGTGACAGCATGGATAGGGTGGTGAAAATCCCTACCTCTCCTGCTGCCCATTAGAGTTCTGGCACCGGAGGGCCTGCCTGGCCTGTTGACCCTGGTCTAGACCTCTCTTCTGTGGCCAGCCAGGAGGTCAGGACCTGTCTTATCACTTGTCATCAGGATAGGAGTTGACAAACAGGCCTGACAGAGTGTACCAAGCTTCTTCAGTTCCTCAGTTAATGATAGCTACAGTTTATGGAGGCCTTCAACTGCAGCAAGTAGGTAACGCCAGCCGTGTTGGTGGGTCTGCCTCAGGACTCTGAGGTAGGTGCTATCTTTTGTGTTTTAACAGTCACGTGGTTGCTAAGCAGCAAAGCCAGGAGTCGATCTTATGTCTGATGACCTCTCTTCTCTACACTCCCCCAAAACCCTTACACACTCTATCGCCAGTCCTTCTGAGGAAGAGGTTGACAACCCAACAGTTAAGCCATATAAGACTCTTCCTTAACCCTTTGCAACTTTCCTAAGTTCAGCCCAGGCCTAAGGTGACTTTTCTACACAGAGCTCCATCCAAGGGGTCCTGTGGTACTTAACATCTCACAATGAGGATAGTCTCCCTGTAGTTTAATTGAAATCTCTTCTGGTATCATGGAAACCCATTTCTTCCTGTCTGAGGCCGCAGTGGGTATATCAAAGCTTCCCATCCTCCTTCTTGTTGGAGGTTCTCATTAGGTCTACTGAATCCCAGATCCCCACCTAAGTTTTACATTTAAACTGAATCTCATGATCGAGCGCAGGAGTTGATGTTTCCTTTAGAACTGACTCCAGGTGGCTTGTGAGCCATCCGGACCTCCAGGCAGGAGAGAGGACAATGAGTCATAGGAGCTGGACCTCTCTGGAATAAATGACTTCCTCCCATGCACCAGCCTCAACCACACTCTTGCTGTCATTCATCTTGAGAATGCCCAGGAGTCTAGGAGGGCTCACTGGAAGAAGCAGGCACCACAAGGAAATCCCCACAAGTGTGCTGAGCTTCTCCGGGAGATAACTGGTGATAACGGATCCTGGGTATTTAAAAGCTAACCATAGGCTGCTACCAGCGGCCAGAGCAGTCCCCCGTAAGGTCACAGCCCTATGGAAGTTGCAAAGCTCCATGTATTATTATACTTGAATAAGAGCAATGTTGTTATTGGGTTGCATCCCCTCGTGCCTGCCCTCCATTCTGTGGACTTCTCACATGGGCTCCTCTCATTTCTCTTTGCCTTCGTACTGTTAGAAATGACTGTTGCCTCCGGTGGCCATGGGGAAGAAGCTGGTGATGGCCCAGAAGCGCGGAGAGACGCGAGCCCTCTGCCTGGGGGTGGCGATGGTCGTGTGTGCCGCCATCACTTACTACATCCTGGGTACCACTGTGCTGCCCCTCTACCAGAAAAGGTACAGATCTCTCCACTGCCTGGATTGACCTATCCAACCGTTGACCCCTCATGGTGGTCTGGGCAGACCAGGCATTCCTCATCCTCAGGCTCAGGGGTTCCAGTGCTGGGGGAACGGAGCAGTAAGAGATTCGCCAGTTAGGTGCAGCATGCCGATGTCATAAGAAACAGCCTGCCGGTGTTGGTGTGATCCTTGGGGTAAGGAGGGGGATCACAATGGCAGATTCTGAGATGGGAGCATGTCTCTTTTTGCCTGGGTTTTCCCAATAAGTAGTTTCTGCACTGAGCAGATATCCGTCCCCTCAAAGTTTAGGCAGGGATCTCAGAGAGTGCTGTGTTCCCTCGTGCCTCACACTCTGTGACATGTCATCCCTCCAGCTTCTAAAGAAGAACTCCTGATTGCTATTGTCTCTGGAACAGACACACAGTGCTCTCCCAGCTCACCCTTTGCTGAGTCTCATGCCCTCCCTATGGGCATATTCTGGCTCCTGACAGCCCTCTCTTGTCTGACAGTGGGTCTCCCCCAGGATACAGGAAGTCACATTCCATTTGCTTGGGAGTTGATGAGTCTCTTGGCCTCTCCTGGGCCTGGTCTGAGTCCGTGCTTTACACTGCTGCAGTTCTGCCAGGCCAGAGTCTTACCCAAGTGAGGCACCGCTGAACAGCCGTGTGCCTCCCAGCTCTATCCTGATACCCTCCAATCCTGACCGTGTCAAGCCCCTCATATAGGTCCTCTTTTGTAGGGGAAAGGCATAGACTCTGAAGCTACTCAGCCCTTGCCTCAGGTGCTGTGTCCCACTCCCCCCCAAAAATACCTCTCCCATGTGAGGGTCTCATCTCTACCTGTGCCTTGGAGATGAGATAGAGAAAAAGGTCTCAGGCTTGGCTGCTCATCACAATCCCATGATGAGCATTTAAAACAACATCAGTGCCTGGGCCCAAGCACCTGAGAAATTCTGCCTCACTTTCTCTAGAGTGGGACTCAGCTAGCTATAGGGATCTTAAAAAAGGAGGAAGAGGAGGAGGAGGGGGAGGGGGAGGGGAGGAGAGGAGAGGGAGGAGAAGGAGAAGGAGAAGGAGAAGGAGAAGGAGAAGGAGAAGGAGAAGGAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGAAGACAACTGTCAGGTGAAGGGTGGCTAGCAAGGTCAGAGAACCATTATGTAGAAAATGTTCAAGAGCCAACACAGATTGTGATTTATCCCAGAGTCCAGGTCTCTAGGACTATGGACTCAGTAGAACATGCTCATAGCAAAACAAAGGTCTCAGCCATGGGTCTCTCCAAAGGCTCTCAGGGAACCAGGGTTTCAAATTGGGTGTGTGTCACCCTTGTCTCTAAGGGATGTTTGTGTGTGTGTTGTCTCCCCAGTGTGTGGACCCAGGAATCCACCTGTCACTTGGTTGAAACCAACATCAAGGACCAGGAAGAGCTGGAGGGCAGGAAGGTGCCCCAGTACCCATGCCTTTGGGTCAATGTATCAGCTGTGGGCAGATGGGCCATGCTGTATCACACAGAAGACACTCGGGATCAAAACCAACAGGTGACAGATGGGGGCTGGGTATATTAGACAGGTCTGTGAGCTTGTCTGCAGCCGACCATGTCTCTAAAGCCAAGATATAGTGACCCACCTCAACTGATTCTTATGGCTGGCTTGAGGTGGAGTCAAGCTCGGATCTTCCATGTTGGAACCAACAGACCTGGGTGGTTTGCATTGCCCCTAATTGGCTGTGCACTGGGCACTGAGGTCCTGTGAGTCTCTATTTCCATCCTAGGAAATGGATGCTAATGCCATACCCAGAAGTGCTATGACCAGAGCACCGGTTTTGCTAAGTCTAGAAGGTTCTCATACATAGCCAGAGTTGAGATGCTCCCGTTGAGATGCTAGGTTGGCAGAGGGTGGGCGCTCAGAGCAGAGAAGCAGTCTTTACTGGTTACTTCTTTCATCAACGGAGCCCGTCAAGGGAGCTGAGTGAATGCGTGGGCCACCTGGGAGCCAGGACTACAGCAACCTCCGTAACAAGCATTTCAGAGACCTCCCCTCATCTGCACCTCCCTTGTTGTTAGTTACCTTCTTAGCCCTCCCTATTGCTTCCTTCTCTCCTTCCCATTCATTCATTCCCTCCATTCATCCAACGACCACTGAGCCTTCCCAGGTCAGGCCCATGGGTCTCAAGAGGAGAGAGTTTATATAGGAACACTAACAGTAGGGAGGGAGGGCTGGTGCTATAGAGTGATAGGTCTCCAGGGTGTTGTCAGTGTGGCCTGGAGTAGAGAAGTGTTGGGCTGGGCTTTTCAAATAGGCAATCCTGTAGCCACAGAAACAAGAGATGAGGGATGCATAGCATCCCAGTGTGTGGTGTGACCTAGCATAGGCATGGGGAGAAGGCTAAGCAAAGGCAGTGGCTAGAAGACTGATTCCAGAAATGCCGTCTGATGGAGTGCCCAGAAGAGGCTGTAGGTCTAAAGTCTGCTGCCTGAGGACCACTTCTGTATAGCTGTGGAATTAATAATAGCAAATGCTTTGGGGCTTTTCAACTCTAGCCATACATGAGAGCCATCTAGACCTAATAAAACCAGAATTCTACATCAGCCAACCGAGGCAGAATCCCTGGAGATAGATCTGTTGGTGCAGCTCCCTAGATGAGTCTAAGGTTGGATGCTATTGCTATGAGCCACTGGAGGCCTAGGGCCCCCAGTCAAGTGACGTTGGGAAGACAGAGCCGGCAGCCATGTAGAGTCATTTACCCGATGGAAGTTAGGCTGCCACAGTCCCCAGGATGAGTGTAGACCTGTCATGGGGATGATATAATAGTCAAAATTGAGAAATGGCAATTGCCTGGTGTGTGTGTGTGTGTTTGGAGATGGTCTCTGTGGGCTCTCCAATGCTGGGGTCACAGAAGGAAGGGGTGGTGGTATATAGAAGTCACATTTGTGGTCATTGTTAGCATGACTCTATGTCGGAAAAGAGCCTCAAGGCCCACAAGGCTCAGCTCCTACCAGTGATTCTTGCTTGCTCTTGGGCATCCAGCAACCATAATGTTTCCCAGGAGTGAGAAAAACATTTTTACAGATAACATGGTTTTGGTGCTATTCTCCTGGCATAGCTCATTCTGAGGCTGCCAGTCCAGAGCTGCCAGAGGTAGCCCGAGCCCTGCTTGAGTTGTGAACAGCATGCATTCTTTTTTCTCTAGTAAGGGGGGGGTGTTAAACCACACACCCACAGACCACAGACAGAGAGTTAAGAGCAGACTGCCTTGCTGGGACAGTCAAGCACATTTCATTCTCTGGCCTAGCATCTGGGTCTGTGGCTGGCTGGGTTGGTAGCACGCCCTCTGGACATGCCAGGCTCTTACTCCTTCTCCATGGCCTGCTCGTCTCTCCCTCCATCAACTTAAGTCTAGGGAAGGGGCTCTGAAGCTCTCTTTGCAGTCTATGCTGTCACGAGTGAAGCCTTAGACTAGAGACAGGGTCTTCATCATTTCCGCTCACACAAATAGCTCAGGGCTGGTTGGACCAGCTGAGGTTCACAATGTCAGGCCACGCAGAAGGGGTAAAATGTCTCAGTCTTTGGCTTGGCCTTGGAGAATGAACTTATGGCTAAGACCTTGACAAAGAGATCAAAAGTATAGAATCTAGAGGATCCCCAAGCACGCAAAAGTCCCTTGGGGTAGGTACAGATCCCTACATCAGAGCTCATGCTTTCAATGGGAAAGCAGCAGTCATTCCAGGTTCATAGATAAGACAGCATTATATTATTATTGTTAATGTTATTGTTTATCATTATTTTGAACGTATAAGATCTTTCTAAGTGCTTTATGTAAGTTTCCTAATTTAATTCCCAGGTAGGCACCACCATAGATGACTTCACAAGGTTTAGGGAGGGTACGCTAGTTGACAAAGTCACACAGCTTGGAAGCTGTGGTTGAACCTGGGCCTACCTGGCTCCACAAAGAAATCTGTGCACAACGGGCCAGGTTACCTGGCGACAGTCCTGCTGTTAAACAGCCTGCAGTGCTCAACGCCTCTGAAAGCCACATTCCCCAGGAGCATCGGCTGTCCCTGGCTTGCGGGAGGGACTTGACCTGCCTGCAGCTCCCCTATTTCCCAGATATTAGCACCACAATGAAGCGTCTCTACACTGCTGGACTGGGAAGCTTAGATGGTAACTGAGTCCCAGGGAGAGACAATAGCTCAACGCTTGCCCATGGGCTTCAGGTTTACACATTTGACCTTGACCATGATGTGGCTAGAGCATCCTTGAACATCGCCATTTCACCTGTGTCCAAACCCCCTAGGGTAGGAACTTATGTTAATGAGCATCCTCCTGGTATCCCACTGAGGTCTCCAAAGAGGTCCACCCTTGAGGTTCACAAGTGACATCCAGTCTTTCTGGTACAGAAAGATAAAAGGCAGGTCTCCACTCCGGGCTGTCTTTCCAGAGCTTTACAGCTGGGTCTCATCAACTCCGCAGGCCAGCAGGTTCCTAATAGCAACTACCAGTGCCAGAGTTTAAATGTGCGTTTTGCTCTGCCTGCCTGGAGCTCTTTTTTGCACTTTCTCTCTTTCCTTTGGATTCTGTCACAGAGCCCCGTGCTGACATATTTTCTTTGGTTCACACAGGATTAGACTTCAAAGAGTCTTCCATTTGAATTTTAGCCAGTATTTTGAAATCCTGAGAGTCTGAATTAAAATCAGGTTTTCTGGCTTCTCTGGATGTATGGGTGCACGACGTGGTGTCTGTTATCCAGAGCAAGAGGTGACAGTTCTGACACCGAGGCAGATGCCAGCTGGTCCCTGTCATTAGCCTGCCTTGCTTCATTTCTCGATGCTACCTGCATGAGCTTGCATATAGAATGTCCCTTGTCCCTGGACTTGTATTACTCAGGATTCTCTCTAGCCCATCACCGTGATATCATTAAACCATCTCAGTAACGAAACCATGAGAGCTCAGAGAGGGTGAGCAACTTGCCTAAGATTTCACAGCAAATAAAATCAGATGCAGGCCTCCAGTCGAGCCCTGCATCCAGGTGTGCGGCATCATGTTGAGTGGCACCAAGACTGCCATCCGTATACCGGTGCCAACCATACTTTAAAGCGGTTGACTCCCAAGCCTGAATCTTTTTCTTATATCCCCCACCCTGGGCCTCTTAGACATGTATATTTAAAAGCCTAAGCACTCCTGCTTCTCCTCCACAGTGCTCCTATATCCCCAGGAACCTGGACAACTACCAGACAGCCTTGGTTGATGTGAAGAAGGTCAGAGCCAATTTCTACAAACACCATAATTTCTATTGCTTTTCTGCACCTCAAGTCAATGAGACCAGTGTTGTGTACCAGCGCCTCTATGGGCCCCAAATCCTCCTCTTCTCCTTCTTCTGGCCCACCTTCCTGCTGACTGGTGGCCTTCTTATCATTGCCATGGTAAAGCTCAACAGGTCCCTCTCTGTCTTGGCAGCTCAGAAGTAGACCAATCTCTTCTGCACAGCAGCATGGAGTCACCAGGAACGGCAGGGGTCCCGGGCAGGCATAATTCTCTTCCTCTTGTCCTCCATTTAATTTGTTCAACCTCTTTGGACAATCATTTCTTGCTCAAGAATGTTTAACAGCTCTCTCCGGTTGACTTCGAAGGGCAAAGGAACTGCCAGTCACAGCTCTCGATCCCCGGCTTCAGTTGGCTCACATCTGTTACCTGCTATGTCACTGTCTACTCCCAAGACGATGAATATCGTCACCTCTGTCCCTATGTGCTCTCTCTTAGTTCCTCAGATACCCACCTTTGACATCCAGGATGCTGTCCTTGGCCAAATTCAGCTTCTTTGAATTGTCATAAAAGCCATAGCTCTCA TCT delins Rnor_6.0

Related Rat Strains
The following Strains have been annotated to Kcnmb1em1Mcwi
SS-Kcnmb1em1Mcwi    


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_019273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles


Additional Information