INPPL1 (inositol polyphosphate phosphatase-like 1)

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Keyword

Gene: INPPL1 (inositol polyphosphate phosphatase-like 1) Homo sapiens

Symbol:

INPPL1

Name:

inositol polyphosphate phosphatase-like 1

Description:

The protein encoded by this gene is an SH2-containing 5'-inositol phosphatase that is involved in the regulation of insulin function. The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling. Additionally, this gene supports metastatic growth in breast cancer and is a valuable biomarker for breast cancer. [provided by RefSeq, Jan 2009]

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

51C protein; inositol polyphosphate phosphatase-like protein 1; INPPL-1; OPSMD; OTTHUMP00000237158; OTTHUMP00000237159; phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2; phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase 2; protein 51C; SH2 domain-containing inositol 5'-phosphatase 2; SH2 domain-containing inositol phosphatase 2; SH2 domain-containing inositol-5'-phosphatase 2; SHIP-2; SHIP2

Orthologs:

Mus musculus : Inppl1 (inositol polyphosphate phosphatase-like 1) MGI
Rattus norvegicus : Inppl1 (inositol polyphosphate phosphatase-like 1)

Latest Assembly:

Human Genome Assembly GRCh37

Position:

Map	Chr	Position	Strand	Source
Human Alternate Assembly CHM1_1	11	71,799,511 - 71,813,821	+	NCBI
Human Genome Assembly HuRef	11	68,229,043 - 68,243,351	+	NCBI
Human Genome Assembly GRCh37	11	71,935,882 - 71,950,191	+	NCBI
Human Genome Assembly Build 36	11	71,613,473 - 71,627,797	+	NCBI
Human Cytogenetic Map	11	q13		NCBI
Human Genome Assembly	11	71,613,472 - 71,627,796		NCBI