S1pr2 (sphingosine-1-phosphate receptor 2) - Rat Genome Database

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Gene: S1pr2 (sphingosine-1-phosphate receptor 2) Mus musculus
Analyze
Symbol: S1pr2
Name: sphingosine-1-phosphate receptor 2
RGD ID: 68467
MGI Page MGI
Description: Predicted to enable G protein-coupled receptor activity and signaling receptor binding activity. Involved in positive regulation of peptidyl-threonine phosphorylation and sphingosine-1-phosphate receptor signaling pathway. Acts upstream of or within negative regulation of excitatory postsynaptic potential. Predicted to be located in membrane. Predicted to be active in cytoplasm and plasma membrane. Is expressed in several structures, including alimentary system; brain; branchial arch; genitourinary system; and sensory organ. Used to study autosomal recessive nonsyndromic deafness 68 and non-Hodgkin lymphoma. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 68. Orthologous to human S1PR2 (sphingosine-1-phosphate receptor 2).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 1100001A16Rik; Edg5; endothelial differentiation G-protein coupled receptor 5; endothelial differentiation, sphingolipid G-protein-coupled receptor, 5; G-protein coupled receptor 13; Gpcr; Gpcr13; H218; LP; LPb2; lysophospholipid receptor B2; S1; S1P receptor 2; S1P receptor Edg-5; S1P2; sphingosine 1-phosphate receptor 2; sphingosine 1-phosphate receptor Edg-5; sphingosine-1-phosphate receptor S1P(2)
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,877,248 - 20,888,089 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,873,657 - 20,888,077 (-)EnsemblGRCm39 Ensembl
GRCm38920,965,952 - 20,976,793 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,962,361 - 20,976,781 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,770,396 - 20,781,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,716,360 - 20,727,183 (-)NCBIMGSCv36mm8
Celera918,234,642 - 18,245,483 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.68NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cytoplasm  (IBA)
glutamatergic synapse  (EXP,IDA)
membrane  (IEA)
plasma membrane  (IBA,ISO)
presynapse  (IDA,IEP)

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal action potential  (IAGP)
abnormal angiogenesis  (IAGP)
abnormal brain wave pattern  (IAGP)
abnormal CNS synaptic transmission  (IAGP)
abnormal excitatory postsynaptic currents  (IAGP)
abnormal inner ear vestibule morphology  (IAGP)
abnormal maternal nurturing  (IAGP)
abnormal nervous system electrophysiology  (IAGP)
abnormal organ of Corti morphology  (IAGP)
abnormal posture  (IAGP)
abnormal Rosenthal canal morphology  (IAGP)
abnormal spleen germinal center morphology  (IAGP)
abnormal spleen marginal zone morphology  (IAGP)
abnormal stria vascularis morphology  (IAGP)
abnormal stria vascularis vasculature morphology  (IAGP)
abnormal strial basal cell morphology  (IAGP)
abnormal strial intermediate cell morphology  (IAGP)
abnormal strial marginal cell morphology  (IAGP)
abnormal tectorial membrane morphology  (IAGP)
abnormal tumor morphology  (IAGP)
abnormal tumor vascularization  (IAGP)
abnormal vascular endothelial cell morphology  (IAGP)
abnormal vestibular labyrinth morphology  (IAGP)
abnormal vestibular system physiology  (IAGP)
absent distortion product otoacoustic emissions  (IAGP)
absent startle reflex  (IAGP)
absent vestibular hair cell stereocilia  (IAGP)
cochlear ganglion degeneration  (IAGP)
cochlear hair cell degeneration  (IAGP)
cochlear inner hair cell degeneration  (IAGP)
cochlear outer hair cell degeneration  (IAGP)
deafness  (IAGP)
decreased B cell apoptosis  (IAGP)
decreased endocochlear potential  (IAGP)
decreased litter size  (IAGP)
decreased otolith number  (IAGP)
decreased vertical activity  (IAGP)
degeneration of organ of Corti supporting cells  (IAGP)
detached Reissner membrane  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
enlarged otoliths  (IAGP)
head tilt  (IAGP)
hemorrhage  (IAGP)
impaired hearing  (IAGP)
impaired righting response  (IAGP)
impaired swimming  (IAGP)
increased angiogenesis  (IAGP)
increased B cell derived lymphoma incidence  (IAGP)
increased B cell number  (IAGP)
increased B cell proliferation  (IAGP)
increased germinal center B cell number  (IAGP)
increased lung endothelial cell migration  (IAGP)
increased lung tumor incidence  (IAGP)
increased miscarriage rate  (IAGP)
increased or absent threshold for auditory brainstem response  (IAGP)
increased spleen germinal center number  (IAGP)
increased spleen germinal center size  (IAGP)
increased T cell number  (IAGP)
increased tumor growth/size  (IAGP)
lethality throughout fetal growth and development, incomplete penetrance  (IAGP)
limb grasping  (IAGP)
organ of Corti degeneration  (IAGP)
otosclerosis  (IAGP)
perinatal lethality, incomplete penetrance  (IAGP)
postnatal lethality, incomplete penetrance  (IAGP)
premature death  (IAGP)
prenatal lethality, incomplete penetrance  (IAGP)
reduced fertility  (IAGP)
seizures  (IAGP)
skin edema  (IAGP)
small scala media  (IAGP)
stria vascularis degeneration  (IAGP)
thin stria vascularis  (IAGP)
tonic-clonic seizures  (IAGP)
utricular macular degeneration  (IAGP)
vestibular hair cell degeneration  (IAGP)
vestibular saccular degeneration  (IAGP)
vestibular saccular macula degeneration  (IAGP)
References

References - curated
# Reference Title Reference Citation
1. Selective loss of sphingosine 1-phosphate signaling with no obvious phenotypic abnormality in mice lacking its G protein-coupled receptor, LP(B3)/EDG-3. Ishii I, etal., J Biol Chem 2001 Sep 7;276(36):33697-704.
2. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
3. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
4. MGDs mouse GO annotations MGD data from the GO Consortium
5. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
6. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
7. Mouse MP Annotation Import Pipeline RGD automated import pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8288218   PMID:9931453   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11553273   PMID:11908758   PMID:12006579   PMID:12401212   PMID:12477932   PMID:12588974   PMID:12810709  
PMID:12904583   PMID:14499732   PMID:14610273   PMID:15138255   PMID:15689381   PMID:15745951   PMID:15764699   PMID:15782199   PMID:15870293   PMID:16141072   PMID:16141073   PMID:16212624  
PMID:16314531   PMID:16319286   PMID:16434032   PMID:16602821   PMID:16631609   PMID:16756949   PMID:16945494   PMID:16980623   PMID:16990495   PMID:17284444   PMID:17287522   PMID:17293497  
PMID:17341687   PMID:17710232   PMID:17719579   PMID:17872461   PMID:17967808   PMID:18003758   PMID:18287559   PMID:18296752   PMID:18323526   PMID:18424450   PMID:18525171   PMID:18799693  
PMID:18804439   PMID:18819098   PMID:18924241   PMID:18955732   PMID:19073640   PMID:19161225   PMID:19261841   PMID:19608972   PMID:19749179   PMID:19903857   PMID:20042570   PMID:20060809  
PMID:20068174   PMID:20194630   PMID:20407207   PMID:20435688   PMID:20458606   PMID:20554039   PMID:20671234   PMID:20702813   PMID:20947824   PMID:21135136   PMID:21256191   PMID:21267068  
PMID:21281624   PMID:21292747   PMID:21319224   PMID:21642988   PMID:21668976   PMID:21677750   PMID:21873635   PMID:21932398   PMID:22019019   PMID:22042977   PMID:22095950   PMID:22096531  
PMID:22140255   PMID:22178384   PMID:22505286   PMID:22606352   PMID:22668972   PMID:22744969   PMID:23106337   PMID:23148237   PMID:23300082   PMID:23337656   PMID:23723450   PMID:23879641  
PMID:24003216   PMID:24021572   PMID:24028747   PMID:24453941   PMID:24602016   PMID:24812668   PMID:24913235   PMID:25111230   PMID:25274307   PMID:25377550   PMID:25512083   PMID:25911610  
PMID:26200183   PMID:26243335   PMID:26459774   PMID:26573295   PMID:26805784   PMID:26903652   PMID:26943364   PMID:27080739   PMID:27224249   PMID:27353364   PMID:27383011   PMID:27582371  
PMID:27612439   PMID:28017639   PMID:28143955   PMID:28248965   PMID:28323616   PMID:28709801   PMID:28943240   PMID:29453251   PMID:29620575   PMID:29662200   PMID:29782549   PMID:30468865  
PMID:30609675   PMID:30655318   PMID:30706444   PMID:30761838   PMID:31003944   PMID:31160320   PMID:31235580   PMID:31415870   PMID:31431671   PMID:31586162   PMID:31875848   PMID:31907354  
PMID:31988136   PMID:32016996   PMID:32647340   PMID:32722120   PMID:32768187   PMID:32945579   PMID:33039527   PMID:33197483   PMID:33341041   PMID:33525436   PMID:33727061   PMID:34502385  
PMID:34555336   PMID:34865521   PMID:35296311   PMID:35333897   PMID:35707833   PMID:35836816   PMID:36229875   PMID:36690339   PMID:36834810   PMID:38007654   PMID:38011768   PMID:38061028  
PMID:38136563  


Genomics

Comparative Map Data
S1pr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39920,877,248 - 20,888,089 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl920,873,657 - 20,888,077 (-)EnsemblGRCm39 Ensembl
GRCm38920,965,952 - 20,976,793 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl920,962,361 - 20,976,781 (-)EnsemblGRCm38mm10GRCm38
MGSCv37920,770,396 - 20,781,237 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36920,716,360 - 20,727,183 (-)NCBIMGSCv36mm8
Celera918,234,642 - 18,245,483 (-)NCBICelera
Cytogenetic Map9A3NCBI
cM Map97.68NCBI
S1PR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381910,221,433 - 10,231,331 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1910,221,433 - 10,231,331 (-)EnsemblGRCh38hg38GRCh38
GRCh371910,332,109 - 10,342,007 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361910,193,109 - 10,202,948 (-)NCBINCBI36Build 36hg18NCBI36
Build 341910,195,519 - 10,202,929NCBI
Celera1910,227,498 - 10,237,335 (-)NCBICelera
Cytogenetic Map19p13.2NCBI
HuRef199,912,564 - 9,922,403 (-)NCBIHuRef
CHM1_11910,332,386 - 10,342,216 (-)NCBICHM1_1
T2T-CHM13v2.01910,347,578 - 10,357,458 (-)NCBIT2T-CHM13v2.0
S1pr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8827,779,452 - 27,790,344 (-)NCBIGRCr8
mRatBN7.2819,503,276 - 19,514,169 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl819,502,627 - 19,523,574 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx823,522,690 - 23,533,589 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0821,820,536 - 21,831,435 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0819,732,951 - 19,743,843 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0821,984,914 - 21,995,806 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl821,984,914 - 21,995,806 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0822,041,266 - 22,061,702 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4819,989,867 - 20,000,759 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1819,989,866 - 20,000,759 (-)NCBI
Celera820,897,794 - 20,908,686 (-)NCBICelera
Cytogenetic Map8q13NCBI
S1pr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554951,529,428 - 1,530,486 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554951,528,963 - 1,530,527 (-)NCBIChiLan1.0ChiLan1.0
S1PR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22015,138,454 - 15,148,379 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11914,137,059 - 14,151,513 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0199,771,888 - 9,781,944 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11910,436,094 - 10,443,955 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1910,436,502 - 10,437,563 (-)Ensemblpanpan1.1panPan2
S1PR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12050,855,505 - 50,862,985 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2050,860,591 - 50,861,649 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2050,725,039 - 50,732,522 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02051,376,931 - 51,384,414 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2051,376,966 - 51,384,411 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12050,583,043 - 50,590,527 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02051,012,253 - 51,019,735 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02051,252,973 - 51,260,455 (+)NCBIUU_Cfam_GSD_1.0
S1pr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405118209,767,641 - 209,774,934 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936659579,867 - 586,885 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936659579,771 - 587,077 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
S1PR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl269,049,270 - 69,057,270 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1269,050,396 - 69,057,270 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2269,377,718 - 69,384,593 (-)NCBISscrofa10.2Sscrofa10.2susScr3
S1PR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.169,281,130 - 9,291,705 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl69,283,529 - 9,284,590 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607410,755,523 - 10,766,082 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
S1pr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248282,390,742 - 2,394,106 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248282,371,750 - 2,419,330 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in S1pr2
242 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:575
Count of miRNA genes:394
Interacting mature miRNAs:435
Transcripts:ENSMUST00000054197
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4142326Tgq19_mtriglyceride QTL 19 (mouse)Not determined121060750Mouse
1300899Chol6_mcholesterol 6 (mouse)Not determined9129902913Mouse
13434920Dcollq1_mdifferential colonization level QTL 1 (mouse)9130341840Mouse
35673312Ari7_mantibody response to influenza 7, day 45, IgG3 (mouse)9780000122211296Mouse
1300849Sles4_msystemic lupus erythmatosus suppressor 4 (mouse)Not determined9910756237306370Mouse
13504833Bglu19_mblood glucose level 19 (mouse)9991076843910768Mouse
1300532Tbs2_mtuberculosis severity 2 (mouse)Not determined91236997046370114Mouse
10043917Obq37_mobesity QTL 37 (mouse)Not determined91339117547391175Mouse
1357637Si5lq2_mserum IGFBP-5 level QTL 2 (mouse)Not determined91541175149411890Mouse
4141591Cq4_mcholesterol QTL 4 (mouse)Not determined91541175149411890Mouse
1301421Lgth4_mbody length 4 (mouse)Not determined91541175149411890Mouse
4141447Cfmq2_mcystic fibrosis modifier QTL 2 (mouse)Not determined91541175149411890Mouse
12790993Adq1_maortic diameter QTL 1 (mouse)91574962749749627Mouse
11354951Pdcc3_mplasmacytoid dentritic cell compartment 3 (mouse)91574962749749627Mouse
12790997Adq2_maortic diameter QTL 2 (mouse)91574962749749627Mouse
12880415V125Dq7_mvitamin D active form serum level QTL 7 (mouse)91601129650011296Mouse
12880416V125Dq8_mvitamin D active form serum level QTL 8 (mouse)91601129650011296Mouse
13504834Hdlq109_mHDL QTL 109 (mouse)91670964150709641Mouse
1357465Vtbt6_mvertebral trabecular bone trait 6 (mouse)Not determined91697884050978943Mouse
1300643Pvcan2_mprotection against vaginal candidiasis 2 (mouse)Not determined91994340653943525Mouse
1301439Morph2_mmorphine antinociception 2 (mouse)Not determined92015336254153492Mouse
1301883Skull12_mskull morphology 12 (mouse)Not determined92030619754306370Mouse
1301045Sluc10_msusceptibility to lung cancer 10 (mouse)Not determined92030619754306370Mouse
10043950Pbft5_mpercent body fat 5 (mouse)Not determined92030619754306370Mouse
4142352Lmr17_mleishmaniasis resistance 17 (mouse)Not determined92030619754306370Mouse
12904939Edlmmq8_mextensor digitorum longus muscle mass QTL 8 (mouse)92085274054852740Mouse

Markers in Region
Edg5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37920,772,375 - 20,772,974UniSTSGRCm37
Celera918,236,621 - 18,237,220UniSTS
Cytogenetic Map9A3UniSTS
cM Map96.0UniSTS
cM Map96.0UniSTS
cM Map96.0UniSTS
Edg5  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38920,967,931 - 20,968,530UniSTSGRCm38
MGSCv37920,772,375 - 20,772,974UniSTSGRCm37
Celera918,236,621 - 18,237,220UniSTS
Cytogenetic Map9A3UniSTS
cM Map96.0UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_010333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006510019 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC170598 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF108020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK003144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK085114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK134275 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK151062 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK159605 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK170436 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK196049 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC096760 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY095108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466522 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L20334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000054197   ⟹   ENSMUSP00000053394
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,873,657 - 20,888,077 (-)Ensembl
GRCm38.p6 Ensembl920,962,361 - 20,976,781 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214218   ⟹   ENSMUSP00000150113
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,879,779 - 20,888,005 (-)Ensembl
GRCm38.p6 Ensembl920,968,483 - 20,976,709 (-)Ensembl
RefSeq Acc Id: ENSMUST00000214333
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,886,414 - 20,888,000 (-)Ensembl
GRCm38.p6 Ensembl920,975,118 - 20,976,704 (-)Ensembl
RefSeq Acc Id: ENSMUST00000216499
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl920,879,545 - 20,885,274 (-)Ensembl
GRCm38.p6 Ensembl920,968,249 - 20,973,978 (-)Ensembl
RefSeq Acc Id: NM_010333   ⟹   NP_034463
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,877,248 - 20,888,089 (-)NCBI
GRCm38920,965,952 - 20,976,793 (-)ENTREZGENE
MGSCv37920,770,396 - 20,781,237 (-)RGD
Celera918,234,642 - 18,245,483 (-)RGD
cM Map9 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006510019   ⟹   XP_006510082
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39920,877,248 - 20,887,878 (-)NCBI
GRCm38920,965,952 - 20,976,584 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_034463   ⟸   NM_010333
- UniProtKB: Q8C3Q7 (UniProtKB/Swiss-Prot),   Q9R236 (UniProtKB/Swiss-Prot),   P52592 (UniProtKB/Swiss-Prot),   Q3U5W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006510082   ⟸   XM_006510019
- Peptide Label: isoform X1
- UniProtKB: Q8C3Q7 (UniProtKB/Swiss-Prot),   Q9R236 (UniProtKB/Swiss-Prot),   P52592 (UniProtKB/Swiss-Prot),   Q3U5W6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000053394   ⟸   ENSMUST00000054197
RefSeq Acc Id: ENSMUSP00000150113   ⟸   ENSMUST00000214218
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P52592-F1-model_v2 AlphaFold P52592 1-352 view protein structure

Promoters
RGD ID:6845114
Promoter ID:MM_KWN:56537
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   ES_Cell,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_010333
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36920,780,954 - 20,781,454 (-)MPROMDB
RGD ID:8668906
Promoter ID:EPDNEW_M12484
Type:initiation region
Name:S1pr2_1
Description:Mus musculus sphingosine-1-phosphate receptor 2 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38920,976,739 - 20,976,799EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:99569 AgrOrtholog
Ensembl Genes ENSMUSG00000043895 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000054197 ENTREZGENE
  ENSMUST00000054197.7 UniProtKB/Swiss-Prot
  ENSMUST00000214218.2 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro EDG5_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S1P_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14739 UniProtKB/Swiss-Prot
MGD MGI:99569 ENTREZGENE
NCBI Gene 14739 ENTREZGENE
PANTHER G-PROTEIN COUPLED RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR22750:SF17 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen S1pr2 PhenoGen
PRINTS EDG5RECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  S1PRECEPTOR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A1L1ST05_MOUSE UniProtKB/TrEMBL
  P52592 ENTREZGENE
  Q3U5W6 ENTREZGENE, UniProtKB/TrEMBL
  Q8BPL4_MOUSE UniProtKB/TrEMBL
  Q8C3Q7 ENTREZGENE
  Q9R236 ENTREZGENE
  S1PR2_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary Q8C3Q7 UniProtKB/Swiss-Prot
  Q9R236 UniProtKB/Swiss-Prot