Gene: Gucy1a3 (guanylate cyclase 1 soluble subunit alpha 3) Rattus norvegicus
Symbol: Gucy1a3
Name: guanylate cyclase 1 soluble subunit alpha 3
Description: ENCODES a protein that exhibits adenylate cyclase activity; cytidylate cyclase activity; GTP binding; INVOLVED IN cGMP biosynthetic process; nitric oxide mediated signal transduction; response to herbicide; PARTICIPATES IN long term depression; purine metabolic pathway; ASSOCIATED WITH acute myocardial infarction (ortholog); Carcinoma, Adenoid Cystic (ortholog); colon cancer (ortholog); FOUND IN guanylate cyclase complex, soluble; protein complex; INTERACTS WITH (S)-10-[(DIMETHYLAMINO)METHYL]-4-ETHYL-4,9-DIHYDROXY-1H-PYRANO[3',4':6,7]INOLIZINO[1,2-B]-QUINOLINE-3,14(4H,12H)-DIONE; 17alpha-ethynylestradiol; 17beta-estradiol
Type: protein-coding
Also known as: GCS-alpha-1; GCS-alpha-3; guanylate cyclase 1, soluble, alpha 3; Guanylate cyclase soluble alpha 1 (GTP pyrophosphate - lyase); guanylate cyclase soluble subunit alpha-3; Guanylate cyclase, soluble, alpha 1 (GTP pyrophosphate - lyase); Gucy1a1; SGC; soluble guanylate cyclase; soluble guanylate cyclase large subunit
Homo sapiens (human) : GUCY1A3 (guanylate cyclase 1 soluble subunit alpha)  HGNC
Mus musculus (house mouse) : Gucy1a3 (guanylate cyclase 1, soluble, alpha 3)  MGI
Chinchilla lanigera (long-tailed chinchilla) : Gucy1a3 (guanylate cyclase 1 soluble subunit alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : GUCY1A3 (guanylate cyclase 1 soluble subunit alpha)
Canis lupus familiaris (dog) : GUCY1A3 (guanylate cyclase 1 soluble subunit alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gucy1a3 (guanylate cyclase 1 soluble subunit alpha)
more info ...
Allele / Splice: Gucy1a3em1Mcwi  
Genetic Models: SS-Gucy1a3em1Mcwi
Latest Assembly: Rnor_6.0 - RGSC Genome Assembly v6.0
Rat AssemblyChrPosition (strand)SourceGenome Browsers
Rnor_6.02181,045,694 - 181,103,321 (-)NCBIRnor6.0rn6Rnor6.0
Rnor_5.02200,453,480 - 200,515,219 (-)NCBIRnor5.0rn5Rnor5.0
RGSC_v3.42173,756,824 - 173,818,316 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12173,705,122 - 173,768,506 (-)NCBI
Celera2161,450,514 - 161,511,622 (-)NCBI
Cytogenetic Map2q34NCBImapview
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
QTLs in Region (Rnor_6.0)
Genetic Models
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Strain Variation

Strain Sequence Variants

Additional Information

External Database Links
Nomenclature History
RGD Curation Notes
More on Gucy1a3
Ensembl Gene
JBrowse: rn5 rn6
NCBI Map Viewer
Vista + UCSC

RGD Object Information
RGD ID: 68436
Created: 2001-07-11
Species: Rattus norvegicus
Last Modified: 2017-07-04
Status: ACTIVE