| 17alpha-ethynylestradiol | affects expression | ISO | RGD:68520 | 6480464 | Ethinyl Estradiol affects the expression of SIGMAR1 mRNA | CTD | PMID:17555576 |
| 17alpha-ethynylestradiol | multiple interactions | ISO | RGD:68520 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIGMAR1 mRNA | CTD | PMID:17942748 |
| 17alpha-ethynylestradiol | increases expression | ISO | RGD:68520 | 6480464 | Ethinyl Estradiol results in increased expression of SIGMAR1 mRNA | CTD | PMID:17942748 |
| 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | RGD:68520 | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of SIGMAR1 mRNA | CTD | PMID:17942748 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | RGD:68520 | 6480464 | Tetrachlorodibenzodioxin affects the expression of SIGMAR1 mRNA | CTD | PMID:21570461 |
| 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of SIGMAR1 mRNA | CTD | PMID:22298810 |
| 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | RGD:68520 | 6480464 | Tetrachlorodibenzodioxin results in increased expression of SIGMAR1 mRNA | CTD | PMID:17942748 |
| 3,3',5-triiodo-L-thyronine | increases expression | EXP | | 6480464 | Triiodothyronine results in increased expression of SIGMAR1 mRNA | CTD | PMID:15953391 |
| 3H-1,2-dithiole-3-thione | increases expression | EXP | | 6480464 | 1,2-dithiol-3-thione results in increased expression of SIGMAR1 mRNA | CTD | PMID:19162173 |
| acetylcholine | multiple interactions | EXP | | 6480464 | [1-(3-(4-(3-chlorophenyl)-1-piperazinyl)propyl)-3,4-dihydro-5-methoxy-2(1H)-quinolinone binds to and results in increased activity of SIGMAR1 protein] which results in increased secretion of Acetylcholine; more ... | CTD | PMID:11907181 |
| aflatoxin B1 | decreases expression | ISO | RGD:68520 | 6480464 | Aflatoxin B1 results in decreased expression of SIGMAR1 mRNA | CTD | PMID:19770486 |
| ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of SIGMAR1 mRNA | CTD | PMID:16483693 |
| benzo[a]pyrene | decreases expression | ISO | RGD:68519 | 6480464 | Benzo(a)pyrene results in decreased expression of SIGMAR1 mRNA | CTD | PMID:20106945 |
| caffeine | decreases expression | EXP | | 6480464 | Caffeine results in decreased expression of SIGMAR1 mRNA | CTD | PMID:20864626 |
| clofibrate | multiple interactions | ISO | RGD:68520 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA; more ... | CTD | PMID:17585979 |
| clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of SIGMAR1 mRNA | CTD | PMID:17602206 |
| clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SIGMAR1 mRNA | CTD | PMID:17602206 |
| cobalt dichloride | decreases expression | ISO | RGD:68519 | 6480464 | cobaltous chloride results in decreased expression of SIGMAR1 mRNA | CTD | PMID:19320972 PMID:19376846 |
| cocaine | multiple interactions | ISO | RGD:68519 | 6480464 | 1-propyl-5-(3-p-tolylisoxazol-5-yl)-1,2,3,6-tetrahydropyridine inhibits the reaction [Cocaine promotes the reaction [[SIGMAR1 protein binds to DRD1 protein] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]]; more ... | CTD | PMID:20956312 |
| cocaine | increases response to substance | ISO | RGD:68520 | 6480464 | SIGMAR1 mRNA results in increased susceptibility to Cocaine | CTD | PMID:11426838 |
| cocaine | decreases response to substance | ISO | RGD:68520 | 6480464 | SIGMAR1 gene mutant form results in decreased susceptibility to Cocaine | CTD | PMID:11006959 |
| cocaine | multiple interactions | ISO | RGD:68520 | 6480464 | Cocaine results in increased activity of and results in increased localization of SIGMAR1 protein; more ... | CTD | PMID:20354174 |
| cocaine | affects binding | ISO | RGD:68520 | 6480464 | Cocaine binds to SIGMAR1 protein | CTD | PMID:12128006 |
| cocaine | affects binding | ISO | RGD:68519 | 6480464 | Cocaine binds to SIGMAR1 protein | CTD | PMID:20956312 |
| copper(2+) sulfate | decreases expression | ISO | RGD:68519 | 6480464 | Copper Sulfate results in decreased expression of SIGMAR1 mRNA | CTD | PMID:19549813 |
| cyclosporin A | decreases expression | ISO | RGD:68519 | 6480464 | Cyclosporine results in decreased expression of SIGMAR1 mRNA | CTD | PMID:20106945 |
| dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of SIGMAR1 mRNA | CTD | PMID:17379624 |
| doxorubicin | decreases expression | EXP | | 6480464 | Doxorubicin results in decreased expression of SIGMAR1 protein | CTD | PMID:17631546 |
| methotrexate | affects expression | ISO | RGD:68520 | 6480464 | Methotrexate affects the expression of SIGMAR1 mRNA | CTD | PMID:18502557 |
| N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of SIGMAR1 mRNA | CTD | PMID:17602206 |
| paclitaxel | increases expression | EXP | | 6480464 | Paclitaxel analog results in increased expression of SIGMAR1 mRNA | CTD | PMID:15585946 |
| paracetamol | multiple interactions | ISO | RGD:68520 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of SIGMAR1 mRNA; more ... | CTD | PMID:17585979 |
| perfluorooctane-1-sulfonic acid | increases expression | EXP | | 6480464 | perfluorooctane sulfonic acid results in increased expression of SIGMAR1 mRNA | CTD | PMID:18692542 |
| pirinixic acid | decreases expression | ISO | RGD:68520 | 6480464 | pirinixic acid results in decreased expression of SIGMAR1 mRNA | CTD | PMID:18445702 |
| pirinixic acid | increases expression | ISO | RGD:68520 | 6480464 | pirinixic acid results in increased expression of SIGMAR1 mRNA | CTD | PMID:15302862 more ... |
| pirinixic acid | increases expression | ISO | RGD:68520 | 6480464 | pirinixic acid results in increased expression of SIGMAR1 mRNA | CTD | PMID:15302862 more ... |
| pirinixic acid | increases expression | ISO | RGD:68520 | 6480464 | pirinixic acid results in increased expression of SIGMAR1 mRNA | CTD | PMID:18301758 more ... |
| pirinixic acid | increases expression | ISO | RGD:68520 | 6480464 | pirinixic acid results in increased expression of SIGMAR1 mRNA | CTD | PMID:20059764 more ... |
| pirinixic acid | multiple interactions | ISO | RGD:68520 | 6480464 | PPARA protein promotes the reaction [pirinixic acid results in increased expression of SIGMAR1 mRNA] | CTD | PMID:20059764 |
| pregnenolone 16alpha-carbonitrile | affects expression | EXP | | 6480464 | Pregnenolone Carbonitrile affects the expression of SIGMAR1 mRNA | CTD | PMID:19162173 |
| scopolamine | multiple interactions | ISO | RGD:68520 | 6480464 | [2-(4-morpholino)ethyl-1-phenylcyclohexane-1-carboxylate binds to and results in increased activity of SIGMAR1 protein] which results in decreased susceptibility to Scopolamine Hydrobromide; more ... | CTD | PMID:12028363 |
| tamoxifen | affects expression | ISO | RGD:68520 | 6480464 | Tamoxifen affects the expression of SIGMAR1 mRNA | CTD | PMID:17555576 |
| valproic acid | affects expression | ISO | RGD:68520 | 6480464 | Valproic Acid affects the expression of SIGMAR1 mRNA | CTD | PMID:17292431 |