Pilra (paired immunoglobin-like type 2 receptor alpha)

Gene: Pilra (paired immunoglobin-like type 2 receptor alpha) Rattus norvegicus

Analyze

Symbol:

Pilra

Name:

paired immunoglobin-like type 2 receptor alpha

RGD ID:

6497409

Description:

Predicted to enable MHC class I protein binding activity. Predicted to act upstream of or within signal transduction. Predicted to be located in cell periphery and membrane. Orthologous to several human genes including PILRA (paired immunoglobin like type 2 receptor alpha); INTERACTS WITH 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

LOC100910669; LOC288568; paired immunoglobulin-like type 2 receptor alpha; paired immunoglobulin-like type 2 receptor alpha-like; RGD1562847; similar to paired immunoglobin-like type 2 receptor alpha

RGD Orthologs

Alliance Genes

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	23,452,626 - 23,464,772 (+)	NCBI		GRCr8
mRatBN7.2	12	17,787,169 - 17,798,149 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	17,787,127 - 17,798,094 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	19,635,530 - 19,649,075 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	20,259,246 - 20,272,791 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	19,324,080 - 19,337,625 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	21,678,550 - 21,689,821 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	21,678,580 - 21,690,678 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	23,699,427 - 23,711,607 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	19,993,748 - 20,006,782 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	20,672,244 - 20,686,137 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

genetic disease (ISO)

pleomorphic xanthoastrocytoma (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(-)-demecolcine (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (ISO)

2,2',4,4'-Tetrabromodiphenyl ether (EXP)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

3-isobutyl-1-methyl-7H-xanthine (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxynon-2-enal (ISO)

6-propyl-2-thiouracil (EXP)

acetohydrazide (ISO)

aflatoxin B1 (ISO)

all-trans-retinoic acid (ISO)

amitrole (EXP)

antirheumatic drug (ISO)

aristolochic acid A (ISO)

arsenous acid (ISO)

azathioprine (ISO)

benzo[a]pyrene (ISO)

Benzo[k]fluoranthene (ISO)

bisphenol A (EXP,ISO)

carbon nanotube (ISO)

chlordecone (ISO)

chloroprene (ISO)

chromium(6+) (ISO)

cisplatin (EXP,ISO)

decabromodiphenyl ether (EXP)

dexamethasone (ISO)

diallyl disulfide (ISO)

Diallyl sulfide (ISO)

diarsenic trioxide (ISO)

diazinon (ISO)

doxorubicin (ISO)

folic acid (ISO)

formaldehyde (ISO)

indometacin (ISO)

iron dichloride (ISO)

Licochalcone B (ISO)

lipopolysaccharide (ISO)

metformin (ISO)

methamphetamine (ISO)

methimazole (EXP)

N-nitrosodiethylamine (EXP)

nickel sulfate (ISO)

okadaic acid (ISO)

oxaliplatin (EXP)

ozone (ISO)

paracetamol (ISO)

piroxicam (ISO)

potassium chromate (ISO)

prednisolone (ISO)

rifampicin (ISO)

rotenone (EXP)

sodium arsenite (ISO)

succimer (ISO)

sulforaphane (ISO)

tetrachloromethane (ISO)

tetraphene (ISO)

thalidomide (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

topotecan (EXP)

tungsten (ISO)

vincristine (ISO)

zoledronic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

signal transduction (ISO)

Cellular Component

cell periphery (IEA)

membrane (IEA)

Molecular Function

MHC class I protein binding (IBA)

protein binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10903717	PMID:20458337

Genomics

Comparative Map Data

Pilra
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	12	23,452,626 - 23,464,772 (+)	NCBI		GRCr8
mRatBN7.2	12	17,787,169 - 17,798,149 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	12	17,787,127 - 17,798,094 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	12	19,635,530 - 19,649,075 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	12	20,259,246 - 20,272,791 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	12	19,324,080 - 19,337,625 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	12	21,678,550 - 21,689,821 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	12	21,678,580 - 21,690,678 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	12	23,699,427 - 23,711,607 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	12	19,993,748 - 20,006,782 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
Celera	12	20,672,244 - 20,686,137 (+)	NCBI		Celera
Cytogenetic Map	12	q12	NCBI

PILRA
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	7	100,371,291 - 100,400,096 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	7	100,367,530 - 100,400,096 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	7	99,971,110 - 99,997,719 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	7	99,809,004 - 99,835,658 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	7	94,700,868 - 94,727,521 (+)	NCBI		Celera
Cytogenetic Map	7	q22.1	NCBI
HuRef	7	94,604,603 - 94,631,320 (+)	NCBI		HuRef
CHM1_1	7	99,901,704 - 99,928,336 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	7	101,611,370 - 101,640,173 (+)	NCBI		T2T-CHM13v2.0
CRA_TCAGchr7v2	7	99,331,154 - 99,357,807 (+)	NCBI

Pilra
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	5	137,820,214 - 137,834,540 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	5	137,820,214 - 137,834,543 (-)	Ensembl		GRCm39 Ensembl
GRCm38	5	137,821,952 - 137,836,278 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	5	137,821,952 - 137,836,281 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	5	138,263,180 - 138,277,506 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	5	136,539,538 - 136,552,953 (-)	NCBI		MGSCv36	mm8
MGSCv36	5	138,053,176 - 138,075,341 (-)	NCBI		MGSCv36	mm8
Celera	5	134,808,357 - 134,844,859 (-)	NCBI		Celera
Cytogenetic Map	5	G2	NCBI
cM Map	5	76.77	NCBI

Pilra
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0	NW_004955573	553,631 - 560,301 (-)	NCBI	ChiLan1.0	ChiLan1.0

PILRA
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	6	9,271,761 - 9,289,374 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	6	10,973,591 - 10,992,596 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	6	9,205,484 - 9,222,778 (-)	NCBI		ROS_Cfam_1.0
UMICH_Zoey_3.1	6	9,057,984 - 9,075,548 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	6	9,035,043 - 9,052,330 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	6	9,217,961 - 9,235,564 (-)	NCBI		UU_Cfam_GSD_1.0

Pilra
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024409344	133,554,300 - 133,564,026 (-)	NCBI		HiC_Itri_2
SpeTri2.0	NW_004936543	472,520 - 482,147 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

LOC100514951
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1	3	8,045,304 - 8,061,902 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	3	7,284,993 - 7,431,188 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

PILRA
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Vero_WHO_p1.0	NW_023666070	3,461,158 - 3,485,773 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Pilra
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624740	16,669,709 - 16,688,110 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Pilra
321 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	38
Count of miRNA genes:	38
Interacting mature miRNAs:	38
Transcripts:	ENSRNOT00000039797
Prediction methods:	Miranda, Rnahybrid
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312418	Kidm41	Kidney mass QTL 41	3.7	0.0001	kidney mass (VT:0002707)	single kidney wet weight to body weight ratio (CMO:0000622)	12	1	19611090	Rat
10755457	Coatc14	Coat color QTL 14		0.01759	coat/hair pigmentation trait (VT:0010463)	pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)	12	1	22591684	Rat
6893681	Bw109	Body weight QTL 109	2.3	0.004	body mass (VT:0001259)	body weight (CMO:0000012)	12	1	23297788	Rat
1581516	Cm56	Cardiac mass QTL 56	4.2	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	12	1	29333307	Rat
1598855	Bp294	Blood pressure QTL 294	3.5		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	1	34851688	Rat
7411660	Foco28	Food consumption QTL 28	10.9	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
9590086	Insglur6	Insulin/glucose ratio QTL 6	18.97	0.001	blood insulin amount (VT:0001560)	calculated plasma insulin level (CMO:0002170)	12	1	42110980	Rat
8694179	Bw150	Body weight QTL 150	2.9	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
7411586	Foco5	Food consumption QTL 5	5.4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411595	Foco9	Food consumption QTL 9	4	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	1	42110980	Rat
7411545	Bw128	Body weight QTL 128	5.2	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	12	1	42110980	Rat
9590147	Scort7	Serum corticosterone level QTL 7	13.61	0.001	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	12	1	42110980	Rat
2303575	Insul14	Insulin level QTL 14	4		blood insulin amount (VT:0001560)	blood insulin level (CMO:0000349)	12	1	42450532	Rat
737979	Pia22	Pristane induced arthritis QTL 22	53.1		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	1	44465750	Rat
634351	Apr5	Acute phase response QTL 5	6.7		blood interleukin-6 amount (VT:0008595)	plasma interleukin-6 level (CMO:0001927)	12	1	44503507	Rat
2302042	Pia38	Pristane induced arthritis QTL 38	3.5	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	1	44503507	Rat
634350	Apr4	Acute phase response QTL 4	6		orosomucoid 1 amount (VT:0010541)	plasma orosomucoid 1 level (CMO:0001467)	12	1172005	46172005	Rat
8552918	Pigfal7	Plasma insulin-like growth factor 1 level QTL 7			blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411547	Bw129	Body weight QTL 129		0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	6	5564495	46669029	Rat
7411597	Foco10	Food consumption QTL 10		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
7411641	Foco19	Food consumption QTL 19	27.7	0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552964	Pigfal17	Plasma insulin-like growth factor 1 level QTL 17	3.5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564495	46669029	Rat
7411588	Foco6	Food consumption QTL 6		0.001	eating behavior trait (VT:0001431)	feed conversion ratio (CMO:0001312)	12	5564495	46669029	Rat
8552912	Pigfal6	Plasma insulin-like growth factor 1 level QTL 6	5		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	12	5564498	46669029	Rat
10059594	Kidm46	Kidney mass QTL 46	3.79	0.025	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	12	6107579	46669029	Rat
1600391	Edcs2	Endometrial carcinoma susceptibility QTL2	3.5	0.01	uterus morphology trait (VT:0001120)	percentage of study population developing endometrioid carcinoma during a period of time (CMO:0001759)	12	6833190	17870186	Rat
1302792	Scl21	Serum cholesterol level QTL 21	3.8	0.0011	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	12	7196730	46669029	Rat
2293086	Iddm30	Insulin dependent diabetes mellitus QTL 30	3.82		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	8449490	28302290	Rat
61331	Eau2	Experimental allergic uveoretinitis QTL 2		0.0005	uvea integrity trait (VT:0010551)	experimental autoimmune uveitis score (CMO:0001504)	12	8525423	28064601	Rat
1300157	Rf21	Renal function QTL 21	4.4		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	12	9318216	32103380	Rat
1549829	Scl48	Serum cholesterol level QTL 48	5		blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	12	9603277	46669029	Rat
2293699	Bss49	Bone structure and strength QTL 49	5.61	0.0001	lumbar vertebra size trait (VT:0010518)	lumbar vertebra trabecular cross-sectional area (CMO:0001692)	12	10474137	46669029	Rat
2300186	Bmd59	Bone mineral density QTL 59	7.1	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	12	10474137	46669029	Rat
1331786	Kidm11	Kidney mass QTL 11	3.571		kidney mass (VT:0002707)	right kidney wet weight (CMO:0000082)	12	11073825	24234895	Rat
1331755	Bp219	Blood pressure QTL 219	3.041		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	28064557	Rat
1331761	Bp218	Blood pressure QTL 218	2.973		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	11073825	45055165	Rat
61404	Bw120	Body weight QTL 120	5.1		body mass (VT:0001259)	body mass index (BMI) (CMO:0000105)	12	12351619	46669029	Rat
1641928	Alcrsp5	Alcohol response QTL 5			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	12	12812385	46669029	Rat
2303569	Gluco44	Glucose level QTL 44	2		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	12	12812385	46669029	Rat
7204484	Bp358	Blood pressure QTL 358		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	12	13008296	19212979	Rat
1549902	Bp269	Blood pressure QTL 269			arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	13182736	46669029	Rat
1549912	Bp268	Blood pressure QTL 268			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	10	13182736	46669029	Rat
2302060	Pia37	Pristane induced arthritis QTL 37	6.1	0.001	blood immunoglobulin amount (VT:0002460)	serum immunoglobulin G1 level (CMO:0002115)	12	13198157	46669029	Rat
61416	Pia4	Pristane induced arthritis QTL 4	8.4		joint integrity trait (VT:0010548)	arthritic paw count (CMO:0001460)	12	13635523	30827399	Rat
61421	Cia12	Collagen induced arthritis QTL 12	4.6		joint integrity trait (VT:0010548)	joint inflammation composite score (CMO:0000919)	12	13635523	35682913	Rat
61443	Btemp2	Thermal response to stress QTL 2	3.3	0.000094	body temperature trait (VT:0005535)	core body temperature (CMO:0001036)	12	15025183	20794014	Rat
631543	Bp83	Blood pressure QTL 83	5.8		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	12	15550826	38478808	Rat
2293684	Bmd26	Bone mineral density QTL 26	4.4	0.0002	femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	12	15872653	32974238	Rat

Markers in Region

RH130677

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	12	23,709,629 - 23,710,295	NCBI	Rnor5.0
Rnor_5.0	12	23,440,936 - 23,441,609	NCBI	Rnor5.0
RGSC_v3.4	12	20,005,700 - 20,006,372	UniSTS	RGSC3.4
RGSC_v3.4	12	19,885,451 - 19,886,116	UniSTS	RGSC3.4
Celera	12	20,685,078 - 20,685,743	UniSTS
Cytogenetic Map	12	q12	UniSTS

RH139788

Rat Assembly	Chr	Position (strand)	Source	JBrowse
Rnor_5.0	12	23,711,309 - 23,711,529	NCBI	Rnor5.0
Rnor_5.0	12	23,442,623 - 23,442,842	NCBI	Rnor5.0
Rnor_5.0	12	23,968,708 - 23,968,852	NCBI	Rnor5.0
RGSC_v3.4	12	20,007,387 - 20,007,606	UniSTS	RGSC3.4
RGSC_v3.4	12	19,884,217 - 19,884,436	UniSTS	RGSC3.4
Celera	12	20,686,758 - 20,686,977	UniSTS
RH 3.4 Map	12	269.0	UniSTS
Cytogenetic Map	12	q12	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system
High
Medium											1
Low	1				11					2	8
Below cutoff	2	9	37	24	8	24	1	1	13	10	2

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001405389	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_008769107	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017598607	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017604539	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	CK478507	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ234400	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000012	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

RefSeq Acc Id:

ENSRNOT00000039797 ⟹ ENSRNOP00000035136

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0 Ensembl	12	21,678,580 - 21,690,678 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000109815 ⟹ ENSRNOP00000097229

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	17,787,127 - 17,798,094 (+)	Ensembl

RefSeq Acc Id:

ENSRNOT00000116295 ⟹ ENSRNOP00000091096

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	12	17,787,240 - 17,797,995 (+)	Ensembl

RefSeq Acc Id:

NM_001405389 ⟹ NP_001392318

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	23,452,697 - 23,463,554 (+)	NCBI
mRatBN7.2	12	17,787,240 - 17,798,097 (+)	NCBI

RefSeq Acc Id:

XM_008769107 ⟹ XP_008767329

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	23,452,626 - 23,464,772 (+)	NCBI
mRatBN7.2	12	17,787,169 - 17,798,149 (+)	NCBI
Rnor_6.0	12	21,678,550 - 21,689,821 (+)	NCBI

Sequence:

show sequence

TAAAGGAAGTTGCTGGCCACAAGGAGGTGGAGATGGAGAGGTCCTGCCCAACTCAGTCCTCCAC
TTGAGAAGGTCTGAGCATGGGTGTCGCTTTACTCTGATTCTCTCTGGAGTCCTGAGCACGCAGT
GTCCCTAGACAGGGCATCCACGCCTTCCTGACAGCCCGGTTGCCCTCACTTCCTGGAAAGAATC
TGGCTATGGCTCGGCTTCTCCTTCTTTTGCTGTCAGCAGCATGTCTGCACAGTGGGAATTCAGC
AGGATATCCAAAAAAGTATGACTATGGTGTCGACCAACCAGCTGTCCTCTCTGGAGTCCAGGGC
AGCTCCATCGAGATCCCCTTCTCCTTCTACTTCCCCTGGAATTTGACCAAGGATCCACAGATGA
GCATAGCCTGGAGATGGAAGAACTTCCATGGGGAATTCATCTACAACTCCACCCAGCCTTTCAT
TCATGAGCATTTTAAGGACCGGCTCATCATGAATTGGACACAGGGTCAGACATCTGGTGTCCTC
AGAATCCTGAACTTTAAGAAGAATGACCAGGCCACATACTTCGGCCGAGTTCTTCTGCAAACAA
CAGAAGGCATGAAGGTGTGGCAGTCAATCCCTGGCACCAACCTCACTGTGACCAATAACACCAG
CACCCCCGCTACACTTCCAAGCACCACCACTGCCACACCTTCTACACACCCCCAAACCGTCACA
ACAGAAGGCATGAAGGACGAGCCAAAGAGTGGCCTGGATCCACAAACCATAATTGTGTTGGCAG
TGGCTGCTGCTGTGTTCCTGGCTGGGGTTTTGGGATTGACAGTGTTCCTCGGGTGGAGGAGAAA
GCAAGGGAGCCATTGGAAAACAGTGAGAAACGTGAGAGTATTGGCCATGAAGGACAATATATGG
ATCCCACAGAGAACCCCAAGGATAATAACATCGTGTATGCCTCCATCTCCCTCTCAAGCCCGAC
ATCACCAGGAGCAGCACCTAGCCTGCCTGTCCAAAAGAACCCCCAGGAAGAGACCGTGTACTCT
ACCATAAAGGCCAAATGAGTGGGTCTGGGTGACACTCTTACGGTGACTTTTGTTTCTGGTGGGA
AGACTCCCAGCTTCCACTGACAACACAGACAGAAATAAACTCACGGGTCACTGAAACCACAGGC
AAACACAGAAATTCGTTCGTCAGAGAGTCTGACCACAGAGAAACTGAGAAACTCCCAAGTTCCC
TTTTCTAACTTCCTAAGCCTTCCTCACAAAAGTAAACAGATACACAGAATCTGCCTACTTAGAA
GAATCTAAGAAGAGAATTGATGTGACCCTTGACTTCTGGCCCTCTAAGGACCCTCCTCTATCAC
TTTTCTAGCAGCCCAAGCAGGGGAATCCTAAATGCTGGCAGCCAGACTCCATGATGTGCACCCT
CATCTGTGACTGTAATAATCAGCTCGGTGTGACTGA

hide sequence

RefSeq Acc Id:

XM_017598607 ⟹ XP_017454096

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	12	23,452,634 - 23,464,772 (+)	NCBI
mRatBN7.2	12	17,787,177 - 17,798,149 (+)	NCBI
Rnor_6.0	12	21,678,550 - 21,689,821 (+)	NCBI

Sequence:

show sequence

TAAAGGAAGTTGCTGGCCACAAGGAGGTGGAGATGGAGAGGTCCTGCCCAACTCAGTCCTCCAC
TTGAGAAGGTCTGAGCATGGGTGTCGCTTTACTCTGATTCTCTCTGGAGTCCTGAGCACGCAGT
GTCCCTAGACAGGGCATCCACGCCTTCCTGACAGCCCGGTTGCCCTCACTTCCTGGAAAGAATC
TGGCTATGGCTCGGCTTCTCCTTCTTTTGCTGTCAGCAGCATGTCTGCACAGTGCAGGATATCC
AAAAAAGTATGACTATGGTGTCGACCAACCAGCTGTCCTCTCTGGAGTCCAGGGCAGCTCCATC
GAGATCCCCTTCTCCTTCTACTTCCCCTGGAATTTGACCAAGGATCCACAGATGAGCATAGCCT
GGAGATGGAAGAACTTCCATGGGGAATTCATCTACAACTCCACCCAGCCTTTCATTCATGAGCA
TTTTAAGGACCGGCTCATCATGAATTGGACACAGGGTCAGACATCTGGTGTCCTCAGAATCCTG
AACTTTAAGAAGAATGACCAGGCCACATACTTCGGCCGAGTTCTTCTGCAAACAACAGAAGGCA
TGAAGGTGTGGCAGTCAATCCCTGGCACCAACCTCACTGTGACCAATAACACCAGCACCCCCGC
TACACTTCCAAGCACCACCACTGCCACACCTTCTACACACCCCCAAACCGTCACAACAGAAGGC
ATGAAGGACGAGCCAAAGAGTGGCCTGGATCCACAAACCATAATTGTGTTGGCAGTGGCTGCTG
CTGTGTTCCTGGCTGGGGTTTTGGGATTGACAGTGTTCCTCGGGTGGAGGAGAAAGCAAGGCCA
GAGGACTAAAGCGGAAACCCCAGCCAGGGAGCCATTGGAAAACAGTGAGAAACGTGAGAGTATT
GGCCATGAAGGACAATATATGGATCCCACAGAGAACCCCAAGGATAATAACATCGTGTATGCCT
CCATCTCCCTCTCAAGCCCGACATCACCAGGAGCAGCACCTAGCCTGCCTGTCCAAAAGAACCC
CCAGGAAGAGACCGTGTACTCTACCATAAAGGCCAAATGAGTGGGTCTGGGTGACACTCTTACG
GTGACTTTTGTTTCTGGTGGGAAGACTCCCAGCTTCCACTGACAACACAGACAGAAATAAACTC
ACGGGTCACTGAAACCACAGGCAAACACAGAAATTCGTTCGTCAGAGAGTCTGACCACAGAGAA
ACTGAGAAACTCCCAAGTTCCCTTTTCTAACTTCCTAAGCCTTCCTCACAAAAGTAAACAGATA
CACAGAATCTGCCTACTTAGAAGAATCTAAGAAGAGAATTGATGTGACCCTTGACTTCTGGCCC
TCTAAGGACCCTCCTCTATCACTTTTCTAGCAGCCCAAGCAGGGGAATCCTAAATGCTGGCAGC
CAGACTCCATGATGTGCACCCTCATCTGTGACTGTAATAATCAGCTCGGTGTGACTGA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001392318	(Get FASTA)	NCBI Sequence Viewer
	XP_008767329	(Get FASTA)	NCBI Sequence Viewer
	XP_017454096	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000091096
	ENSRNOP00000091096.1
	ENSRNOP00000097229
	ENSRNOP00000097229.1

RefSeq Acc Id:	XP_008767329 ⟸ XM_008769107
- Peptide Label:	isoform X2
- UniProtKB:	A0A8I6ADV0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARLLLLLLSAACLHSGNSAGYPKKYDYGVDQPAVLSGVQGSSIEIPFSFYFPWNLTKDPQMSI AWRWKNFHGEFIYNSTQPFIHEHFKDRLIMNWTQGQTSGVLRILNFKKNDQATYFGRVLLQTTE GMKVWQSIPGTNLTVTNNTSTPATLPSTTTATPSTHPQTVTTEGMKDEPKSGLDPQTIIVLAVA AAVFLAGVLGLTVFLGWRRKQGSHWKTVRNVRVLAMKDNIWIPQRTPRIITSCMPPSPSQARHH QEQHLACLSKRTPRKRPCTLP hide sequence

RefSeq Acc Id:	XP_017454096 ⟸ XM_017598607
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6B5H6 (UniProtKB/TrEMBL), A0A8I6ADV0 (UniProtKB/TrEMBL)
- Sequence:	show sequence MARLLLLLLSAACLHSAGYPKKYDYGVDQPAVLSGVQGSSIEIPFSFYFPWNLTKDPQMSIAWR WKNFHGEFIYNSTQPFIHEHFKDRLIMNWTQGQTSGVLRILNFKKNDQATYFGRVLLQTTEGMK VWQSIPGTNLTVTNNTSTPATLPSTTTATPSTHPQTVTTEGMKDEPKSGLDPQTIIVLAVAAAV FLAGVLGLTVFLGWRRKQGQRTKAETPAREPLENSEKRESIGHEGQYMDPTENPKDNNIVYASI SLSSPTSPGAAPSLPVQKNPQEETVYSTIKAK hide sequence

RefSeq Acc Id:

ENSRNOP00000035136 ⟸ ENSRNOT00000039797

RefSeq Acc Id:

ENSRNOP00000097229 ⟸ ENSRNOT00000109815

RefSeq Acc Id:

ENSRNOP00000091096 ⟸ ENSRNOT00000116295

RefSeq Acc Id:	NP_001392318 ⟸ NM_001405389
- Peptide Label:	precursor

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-F1M5V8-F1-model_v2	AlphaFold	F1M5V8	1-291	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:6497409	AgrOrtholog
BioCyc Gene	G2FUF-19760	BioCyc
Ensembl Genes	ENSRNOG00000033017	Ensembl
	ENSRNOG00000062779	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000109815.1	UniProtKB/TrEMBL
	ENSRNOT00000116295.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
NCBI Gene	LOC100910669	ENTREZGENE
PANTHER	PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR	UniProtKB/TrEMBL
	PAIRED IMMUNOGLOBULIN-LIKE TYPE 2 RECEPTOR ALPHA	UniProtKB/TrEMBL
PhenoGen	Pilra	PhenoGen
RatGTEx	ENSRNOG00000033017	RatGTEx
	ENSRNOG00000062779	RatGTEx
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0A8I6ADV0	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6B5H6	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2021-11-05	Pilra	paired immunoglobin-like type 2 receptor alpha	LOC100910669	paired immunoglobulin-like type 2 receptor alpha-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2021-03-09	LOC100910669	paired immunoglobulin-like type 2 receptor alpha-like	RGD1562847	similar to paired immunoglobin-like type 2 receptor alpha	Data merged from RGD:1562847	737654	PROVISIONAL
2015-10-27	RGD1562847	similar to paired immunoglobin-like type 2 receptor alpha	Pilra	paired immunoglobin-like type 2 receptor alpha	Name and Symbol changed	629549	APPROVED
2013-05-24	Pilra	paired immunoglobin-like type 2 receptor alpha	LOC687533	similar to paired immunoglobin-like type 2 receptor alpha	Data merged from RGD:1584232	1643240	APPROVED
2012-07-05	LOC100910669	paired immunoglobulin-like type 2 receptor alpha-like			Symbol and Name status set to provisional	70820	PROVISIONAL
2008-03-06	Pilra	paired immunoglobin-like type 2 receptor alpha	RGD1562847_predicted	similar to paired immunoglobin-like type 2 receptor alpha (predicted)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2006-11-19	LOC687533	similar to paired immunoglobin-like type 2 receptor alpha			Symbol and Name status set to provisional	70820	PROVISIONAL
2006-03-07	RGD1562847_predicted	similar to paired immunoglobin-like type 2 receptor alpha (predicted)	LOC288568	similar to paired immunoglobin-like type 2 receptor alpha	Symbol and Name status set to approved	1299863	APPROVED
2006-02-09	LOC288568	similar to paired immunoglobin-like type 2 receptor alpha			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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