Islr2 (immunoglobulin superfamily containing leucine-rich repeat 2) - Rat Genome Database

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Pathways
Gene: Islr2 (immunoglobulin superfamily containing leucine-rich repeat 2) Rattus norvegicus
Analyze
Symbol: Islr2
Name: immunoglobulin superfamily containing leucine-rich repeat 2
RGD ID: 6497037
Description: Predicted to be involved in positive regulation of axon extension. Predicted to be located in plasma membrane. Predicted to be active in cell surface. Orthologous to human ISLR2 (immunoglobulin superfamily containing leucine rich repeat 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A; gentamycin.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: immunoglobulin superfamily containing leucine-rich repeat protein 2; immunoglobulin superfamily containing leucine-rich repeat protein 2-like; LOC100910729
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8867,504,042 - 67,512,125 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl867,504,037 - 67,513,708 (-)EnsemblGRCr8
mRatBN7.2858,608,165 - 58,616,246 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl858,608,709 - 58,614,650 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx864,138,884 - 64,144,805 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0862,416,441 - 62,422,362 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0860,281,015 - 60,286,934 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd868,328,291 - 68,334,227 (-)NCBI
Lyon_Normotensive870,496,360 - 70,502,280 (-)NCBI
Lyon_Hypertensive868,952,180 - 68,958,116 (-)NCBI
F344_StmMcwi860,362,947 - 60,368,886 (-)NCBI
Rnor_6.0862,983,333 - 62,991,401 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl862,984,552 - 62,987,182 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0862,759,381 - 62,767,420 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera858,072,341 - 58,076,455 (-)NCBICelera
Cytogenetic Map8q24NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
cell surface  (IBA,ISO)
plasma membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:19755105  


Genomics

Comparative Map Data
Islr2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8867,504,042 - 67,512,125 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl867,504,037 - 67,513,708 (-)EnsemblGRCr8
mRatBN7.2858,608,165 - 58,616,246 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl858,608,709 - 58,614,650 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx864,138,884 - 64,144,805 (-)NCBIUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0862,416,441 - 62,422,362 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0860,281,015 - 60,286,934 (-)NCBIUTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd868,328,291 - 68,334,227 (-)NCBI
Lyon_Normotensive870,496,360 - 70,502,280 (-)NCBI
Lyon_Hypertensive868,952,180 - 68,958,116 (-)NCBI
F344_StmMcwi860,362,947 - 60,368,886 (-)NCBI
Rnor_6.0862,983,333 - 62,991,401 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl862,984,552 - 62,987,182 (-)EnsemblRnor_6.0 Ensemblrn6Rnor6.0
Rnor_5.0862,759,381 - 62,767,420 (-)NCBIRnor_5.0Rnor_5.0rn5
Celera858,072,341 - 58,076,455 (-)NCBICelera
Cytogenetic Map8q24NCBI
ISLR2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381574,100,318 - 74,141,826 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1574,100,311 - 74,138,540 (+)EnsemblGRCh38.p14 Ensemblhg38GRCh38
GRCh371574,421,715 - 74,429,143 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361572,209,998 - 72,216,196 (+)NCBIBuild 36Build 36hg18NCBI36
Celera1551,368,842 - 51,376,270 (+)NCBICelera
Cytogenetic Map15q24.1NCBI
HuRef1551,215,500 - 51,222,928 (+)NCBIHuRef
CHM1_11574,539,906 - 74,547,334 (+)NCBICHM1_1
T2T-CHM13v2.01571,966,233 - 72,007,742 (+)NCBIT2T-CHM13v2.0
Islr2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39958,103,580 - 58,113,563 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl958,103,580 - 58,111,602 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38958,196,297 - 58,204,319 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl958,196,297 - 58,204,319 (-)EnsemblGRCm38.p6 Ensemblmm10GRCm38
MGSCv37958,044,104 - 58,052,126 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36957,994,434 - 57,999,852 (-)NCBIMGSCv36mm8
Celera955,430,464 - 55,438,488 (-)NCBICelera
Cytogenetic Map9BNCBI
cM Map931.63NCBI
Islr2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554503,636,469 - 3,645,773 (-)EnsemblChiLan1.0 Ensembl
ChiLan1.0NW_0049554503,636,575 - 3,645,521 (-)NCBIChiLan1.0ChiLan1.0
ISLR2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21663,323,132 - 63,360,611 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11567,486,720 - 67,524,194 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01553,066,685 - 53,075,324 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11572,689,348 - 72,698,800 (+)NCBIPanPan1.1PanPan1.1panPan2
ISLR2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13037,289,609 - 37,297,437 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3037,293,986 - 37,319,879 (+)EnsemblCanFam3.1 EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha3037,224,954 - 37,233,047 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.03037,496,398 - 37,504,459 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3037,501,047 - 37,503,290 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13037,448,501 - 37,456,301 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03037,474,394 - 37,482,515 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03037,730,003 - 37,738,064 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Islr2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mIctTri1.hap1510,301,924 - 10,314,860 (-)NCBImIctTri1.hap1
HiC_Itri_2NW_024408640115,328,592 - 115,343,837 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647133,187,014 - 33,191,134 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493647133,182,217 - 33,191,900 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ISLR2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl759,386,241 - 59,388,481 (-)EnsemblSscrofa11.1 EnsemblsusScr11Sscrofa11.1
Sscrofa11.1759,385,021 - 59,393,185 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2764,003,002 - 64,011,381 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ISLR2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mChlSab1.0.hap12649,934,265 - 49,943,771 (+)NCBImChlSab1.0.hap1
Vero_WHO_p1.0NW_023666048132,260,488 - 132,270,664 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
ChlSab1.1269,352,549 - 9,362,050 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl269,352,472 - 9,358,304 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Islr2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624781444,184 - 452,543 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
HetGla_female_1.0 EnsemblNW_004624781444,192 - 452,276 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
Naked mole-rat maternal Ensembl2735,473,758 - 35,482,335 (+)Ensembl
Islr2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1852,071,626 - 52,079,704 (-)NCBIRrattus_CSIRO_v1Rrattus_CSIRO_v1

Variants

.
Variants in Islr2
70 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:48
Count of miRNA genes:41
Interacting mature miRNAs:47
Transcripts:ENSRNOT00000070885
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
4889938Bss89Bone structure and strength QTL 893.8tibia size trait (VT:0100001)tibia cortical bone volume (CMO:0001725)85899169791341052Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)861019838121662124Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
8662823Vetf5Vascular elastic tissue fragility QTL 51.9artery integrity trait (VT:0010639)patent ductus arteriosus score (CMO:0002566)863404444108404444Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84961020468373388Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)855428333127966348Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
10402857Bp380Blood pressure QTL 3800.95arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
5684973Bss100Bone structure and strength QTL 1004.7tibia area (VT:1000281)tibia area measurement (CMO:0001382)85899169791341052Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat
1300177Cm2Cardiac mass QTL 23.65heart mass (VT:0007028)heart weight (CMO:0000017)863141536109261840Rat
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
12879878Bw183Body weight QTL 1830.001body mass (VT:0001259)body weight (CMO:0000012)862848139107848139Rat
1549908Neudeg1Neurodegradation QTL 15.50nervous system integrity trait (VT:0010566)logarithm of the ratio of the lesioned side motor neuron count to contralateral side motor neuron count (CMO:0001986)858337123103337123Rat
12879879Cm99Cardiac mass QTL 990.001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)862848139107848139Rat
1331804Cm30Cardiac mass QTL 303.77443heart mass (VT:0007028)heart wet weight (CMO:0000069)862970527107970527Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
12879880Cm100Cardiac mass QTL 1000.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)862848139107848139Rat
12879881Cm101Cardiac mass QTL 1010.001heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)862848139107848139Rat
12879882Am8Aortic mass QTL 80.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)862848139107848139Rat
12879883Kidm65Kidney mass QTL 650.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)862848139107848139Rat
71120Niddm21Non-insulin dependent diabetes mellitus QTL 213.73blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)866992095111992095Rat
1358912Bw51Body weight QTL 512.95body mass (VT:0001259)body weight (CMO:0000012)860248093105248093Rat
2313086Bss60Bone structure and strength QTL 604.10.0001tibia length (VT:0004357)tibia length (CMO:0000450)85899169791341052Rat
2293697Bmd39Bone mineral density QTL 39femur strength trait (VT:0010010)femur total energy absorbed before break (CMO:0001677)862848139107848139Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
1331837Bw23Body weight QTL 234.190.00007body mass (VT:0001259)body weight (CMO:0000012)855428416107963099Rat
1331838Niddm61Non-insulin dependent diabetes mellitus QTL 613.530.0004blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)862963099107963099Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
631664Hcar3Hepatocarcinoma resistance QTL 32.90.0005liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)862982864107982864Rat
2301402Bp316Blood pressure QTL 3160.005arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)862848139107848139Rat

Markers in Region
RH131010  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2858,608,266 - 58,608,485 (+)MAPPERmRatBN7.2
Rnor_6.0862,983,435 - 62,983,653NCBIRnor6.0
Rnor_5.0862,759,483 - 62,759,701UniSTSRnor5.0
Celera858,070,985 - 58,071,203UniSTS
RH 3.4 Map8676.2UniSTS
AU048965  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2858,613,457 - 58,613,740 (+)MAPPERmRatBN7.2
Rnor_6.0862,988,626 - 62,988,908NCBIRnor6.0
Rnor_5.0862,764,674 - 62,764,956UniSTSRnor5.0
Celera858,076,114 - 58,076,396UniSTS
Islr2  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2858,610,164 - 58,611,294 (+)MAPPERmRatBN7.2
Rnor_6.0862,985,333 - 62,986,462NCBIRnor6.0
Rnor_5.0862,761,381 - 62,762,510UniSTSRnor5.0
Celera858,072,821 - 58,073,950UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
273 132 674 1508 4013 430 1115 133 294 376 278 151 4272 2380 412 3923 38 1131 734 874 148 146

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001399427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006243179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766373 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596041 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596042 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017596043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017603542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082403 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082404 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082405 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082408 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039082410 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063264716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000070885   ⟹   ENSRNOP00000064244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl867,504,300 - 67,509,694 (-)Ensembl
mRatBN7.2 Ensembl858,608,709 - 58,614,650 (-)Ensembl
Rnor_6.0 Ensembl862,984,552 - 62,987,182 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000128216   ⟹   ENSRNOP00000099630
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl867,504,302 - 67,512,917 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000149205   ⟹   ENSRNOP00000111974
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl867,504,298 - 67,508,222 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000164549   ⟹   ENSRNOP00000100631
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl867,504,037 - 67,513,708 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000169514   ⟹   ENSRNOP00000108059
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl867,504,037 - 67,512,590 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000170804   ⟹   ENSRNOP00000108710
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl867,504,061 - 67,512,393 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000172539   ⟹   ENSRNOP00000112570
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl867,504,287 - 67,510,842 (-)Ensembl
RefSeq Acc Id: NM_001399427   ⟹   NP_001386356
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,509,981 (-)NCBI
mRatBN7.2858,608,165 - 58,614,104 (-)NCBI
Dahl_SR_JrHsd868,328,291 - 68,334,227 (-)NCBI
Lyon_Normotensive870,496,360 - 70,502,280 (-)NCBI
Lyon_Hypertensive868,952,180 - 68,958,116 (-)NCBI
F344_StmMcwi860,362,947 - 60,368,886 (-)NCBI
RefSeq Acc Id: XM_006243178   ⟹   XP_006243240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,510,722 (-)NCBI
mRatBN7.2858,608,165 - 58,614,881 (-)NCBI
Rnor_6.0862,983,333 - 62,989,850 (-)NCBI
Rnor_5.0862,759,381 - 62,767,420 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008766373   ⟹   XP_008764595
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,512,125 (-)NCBI
mRatBN7.2858,608,165 - 58,616,246 (-)NCBI
Rnor_6.0862,983,333 - 62,991,401 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017596042   ⟹   XP_017451531
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,510,039 (-)NCBI
mRatBN7.2858,608,165 - 58,614,339 (-)NCBI
Rnor_6.0862,983,333 - 62,989,425 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039082403   ⟹   XP_038938331
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,509,978 (-)NCBI
mRatBN7.2858,608,165 - 58,614,104 (-)NCBI
RefSeq Acc Id: XM_039082404   ⟹   XP_038938332
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,510,722 (-)NCBI
mRatBN7.2858,608,165 - 58,614,882 (-)NCBI
RefSeq Acc Id: XM_039082405   ⟹   XP_038938333
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,510,039 (-)NCBI
mRatBN7.2858,608,165 - 58,614,162 (-)NCBI
RefSeq Acc Id: XM_039082408   ⟹   XP_038938336
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,509,977 (-)NCBI
mRatBN7.2858,608,165 - 58,614,105 (-)NCBI
RefSeq Acc Id: XM_039082409   ⟹   XP_038938337
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,510,722 (-)NCBI
mRatBN7.2858,608,165 - 58,614,883 (-)NCBI
RefSeq Acc Id: XM_039082410   ⟹   XP_038938338
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,512,125 (-)NCBI
mRatBN7.2858,608,165 - 58,616,141 (-)NCBI
RefSeq Acc Id: XM_063264716   ⟹   XP_063120786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8867,504,042 - 67,512,125 (-)NCBI
RefSeq Acc Id: XP_006243240   ⟸   XM_006243178
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008764595   ⟸   XM_008766373
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017451531   ⟸   XM_017596042
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000064244   ⟸   ENSRNOT00000070885
RefSeq Acc Id: XP_038938338   ⟸   XM_039082410
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938337   ⟸   XM_039082409
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938332   ⟸   XM_039082404
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938333   ⟸   XM_039082405
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938336   ⟸   XM_039082408
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038938331   ⟸   XM_039082403
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: NP_001386356   ⟸   NM_001399427
- Peptide Label: precursor
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063120786   ⟸   XM_063264716
- Peptide Label: isoform X1
- UniProtKB: M0R4G0 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000108710   ⟸   ENSRNOT00000170804
Ensembl Acc Id: ENSRNOP00000111974   ⟸   ENSRNOT00000149205
Ensembl Acc Id: ENSRNOP00000100631   ⟸   ENSRNOT00000164549
Ensembl Acc Id: ENSRNOP00000099630   ⟸   ENSRNOT00000128216
Ensembl Acc Id: ENSRNOP00000108059   ⟸   ENSRNOT00000169514
Ensembl Acc Id: ENSRNOP00000112570   ⟸   ENSRNOT00000172539
Protein Domains
Ig-like

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R4G0-F1-model_v2 AlphaFold M0R4G0 1-746 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:6497037 AgrOrtholog
BioCyc Gene G2FUF-30275 BioCyc
Ensembl Genes ENSRNOG00000050714 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000070885 ENTREZGENE
  ENSRNOT00000070885.4 UniProtKB/TrEMBL
  ENSRNOT00000128216 ENTREZGENE
  ENSRNOT00000128216.1 UniProtKB/TrEMBL
  ENSRNOT00000149205 ENTREZGENE
  ENSRNOT00000149205.1 UniProtKB/TrEMBL
  ENSRNOT00000164549 ENTREZGENE
  ENSRNOT00000164549.1 UniProtKB/TrEMBL
  ENSRNOT00000169514.1 UniProtKB/TrEMBL
  ENSRNOT00000170804.1 UniProtKB/TrEMBL
  ENSRNOT00000172539 ENTREZGENE
  ENSRNOT00000172539.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.10 UniProtKB/TrEMBL
  3.80.10.10 UniProtKB/TrEMBL
InterPro Cys-rich_flank_reg_C UniProtKB/TrEMBL
  Ig-like_dom UniProtKB/TrEMBL
  Ig-like_dom_sf UniProtKB/TrEMBL
  Ig-like_fold UniProtKB/TrEMBL
  Ig_sub UniProtKB/TrEMBL
  L_dom-like UniProtKB/TrEMBL
  Leu-rich_rpt UniProtKB/TrEMBL
  Leu-rich_rpt_typical-subtyp UniProtKB/TrEMBL
KEGG Report rno:100910729 UniProtKB/TrEMBL
NCBI Gene LOC100910729 ENTREZGENE
PANTHER IG(IMMUNOGLOBULIN) AND LRR(LEUCINE RICH REPEAT) DOMAINS UniProtKB/TrEMBL
  IMMUNOGLOBULIN SUPERFAMILY CONTAINING LEUCINE-RICH REPEAT PROTEIN 2 UniProtKB/TrEMBL
Pfam LRR_8 UniProtKB/TrEMBL
PhenoGen Islr2 PhenoGen
PROSITE IG_LIKE UniProtKB/TrEMBL
  LRR UniProtKB/TrEMBL
RatGTEx ENSRNOG00000050714 RatGTEx
SMART LRR_TYP UniProtKB/TrEMBL
  LRRCT UniProtKB/TrEMBL
  SM00409 UniProtKB/TrEMBL
Superfamily-SCOP L domain-like UniProtKB/TrEMBL
  SSF48726 UniProtKB/TrEMBL
UniProt M0R4G0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-06-10 Islr2  immunoglobulin superfamily containing leucine-rich repeat 2  LOC100910729  immunoglobulin superfamily containing leucine-rich repeat protein 2-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100910729  immunoglobulin superfamily containing leucine-rich repeat protein 2-like      Symbol and Name status set to provisional 70820 PROVISIONAL